The dithiocarbsmates are commonly used worldwide as an agricultural fungicide because they are inexpensive and known to be highly effective, A 37 year old male farmer visited our department because of skin rashes on the face, neck and both handa for three years. Because the patch test results revealed a strong positive reaction to dithiocarbamates, and the irritant reaction to orthodichlorobenzen and the biopsy specimen taken from the lesion of dorsum of hand showed the findings of allergic contact dermatitis, the diagnosis of allergic contact dermatitis due to dithiocarbamate was made. The skin lesions were cleared after avoicing the causative agent along with consertatve treatment. There was no relapse during the one year follow up period.
Adult ; Biopsy ; Dermatitis, Allergic Contact* ; Diagnosis ; Exanthema ; Follow-Up Studies ; Hand ; Humans ; Male ; Neck ; Patch Tests ; Recurrence ; Skin

After the performance of 100 coronary cineangiographies in 100 paitents who were adminitted to Soonchunhyang University Hospital under the diagnosis of ischemic heart disease from July 1986 to October 1987, we observed the coronary collateral circulation and measured the ejection fraction, circumferential fiber shortening, left ventricular end-diastolic pressure and pulmonary artery wedge pressure in 52 paitents who had 50% or more stenosis in one or more coroanry arteries. The results were as follow : 1) The collaterall circulation was observed in 16 patients(30.8%) of the 52 patients and it was developed mainly(87.5) in patients with 90% or more coronary artery stenosis. In patients with stenosis of less than 90%, however, collateral circulation was observed rarely(12.5%). 2) The left ventricular wall motion abnormality was severe in the group without collateral circulation. 3) The collteral circulation was most frequently developed in patients with severe right coronary artery stenosis and most of the routes were supplied from contralateral coronary arteries. 4) There was no significant difference in ejection fraction, circumferential fiber shortening, left ventricular end-diastoic pressure and pulmonary artery wedge pressure between the 2 groups with and without coronary artery collateral circulation.
Arteries ; Cineangiography ; Collateral Circulation* ; Constriction, Pathologic ; Coronary Angiography ; Coronary Stenosis ; Coronary Vessels ; Diagnosis ; Humans ; Myocardial Ischemia ; Pulmonary Wedge Pressure ; Ventricular Function, Left*

Caroli disease (CD) is a rare congenital malformation of the liver characterized by non-obstructive, segmental, cystic dilatation of the intrahepatic bile ducts (IHDs). The clinical course is usually asymptomatic for the first 5–20 years, and symptoms may seldom occur throughout the patient’s life. Bile stagnation leads to recurrent episodes of cholangitis, stone formation, or liver abscesses, and biliary cirrhosis usually occurs years later. Here we report on a 42-year-old man diagnosed with diffuse-type CD with a characteristic central dot sign, who had multiple intrahepatic and common bile duct (CBD) stones. CBD stones were treated successfully with endoscopic retrograde cholangiopancreatography (ERCP).
Adult ; Bile ; Bile Ducts, Intrahepatic ; Caroli Disease* ; Cholangiopancreatography, Endoscopic Retrograde ; Cholangitis ; Choledocholithiasis ; Common Bile Duct* ; Dilatation ; Humans ; Liver ; Liver Abscess ; Liver Cirrhosis, Biliary

No abstract available.
*Colorectal Neoplasms ; Humans

PURPOSE: This study was performed to determine the usefulness of three-dimensional computed tomography (3D-CT) in measuring periacetabular osteolysis by comparing the real volume of osteolysis in revision surgery. MATERIALS AND METHODS: Twnety-three patients who had undergone revision surgery due to periacetabular osteolysis but not included septic osteolysis and implant loosening. The mean age of patients at the time of surgery was 55.2 years. And the mean time interval between the primary total hip arthroplasty and revision surgery was 13.3 years. We measured the polyethylene wear in plain radiographs using computer assisted vector wear analysis program, the volume of acetabular osteolytic lesions in high-resolution spiral CT scans using Rapidia 3D software version 2.8 algorithms before the revision surgery were performed. Intraoperative real osteolytic volume was calculated as the sum of the volumetric increments of the acetabular cup and impacted allo-cancellous bone volume. RESULTS: Strong correlation was found between the volume of acetabular osteolytic lesions measured on 3D-CT and intraoperative real osteolytic volume which was calculated as the sum of the volumetric increments of the acetabular cup and impacted allo-cancellous bone volume. CONCLUSION: 3D-CT is considered a useful method for assessing and measuring the volume of periacetabular osteolysis before revision surgery.
Acetabulum ; Arthroplasty ; Arthroplasty, Replacement, Hip* ; Humans ; Methods ; Osteolysis* ; Polyethylene ; Tomography, Spiral Computed

Biliary-enteric fistula is in 0.5% to 5% of patients undergoing biliary tract surgery. The most common cause of biliary-enteric fistula is gallstones and their complications, Much less common causes are complieation of peptic ulcer, malignancy, trauma, and rarely, Crohns, disease. The most common type of biliary-enteric fistula is cholecysto-duadenal. Cholecysto-colic, cholecysto-gastric, and choledocho-duodenal fistula are reported much less frequently. The combination of cholecysto-duodenal fistula with cholecysto-colic fistula is a very rare. Symptoms are generally nonspecific, so diagnosis has depended on plain film of abdomen and barium studies. Recently, endoscopic examination and cannulation of the fistula for precise radiographic delineation will help to make a diagnosis. A 78-year-old man was admitted our hospital because of epigastric discomfort, indigestion, nausea and vomiting for 10 days. He was confirmed as cholecysto-duodeno-colic fistula by gastroduodenoscopy, colonoscopy, and endoscopic cholangio-graphic techniques. So, we report a case of cholecysto-duodeno-colic fistula of the patient with a review of relevant literatures.
Abdomen ; Aged ; Barium ; Biliary Tract ; Catheterization ; Colic* ; Colonoscopy ; Diagnosis ; Dyspepsia ; Fistula* ; Gallstones ; Humans ; Nausea ; Peptic Ulcer ; Vomiting

PURPOSE: The easy recognition and characterization of a discrete or fixed subaortic ridge by echocardiography provides a method for prospective study of the coexistence of ventricular septal defect (VSD) and subaortic ridge. In the presence of a VSD, a subaortic ridge may be clinically silent, but the obstruction can progress if the VSD is surgically or spontaneously closed. This study was carried out to test the hypothesis that the presence of a subaortic ridge associated with a VSD is related abnormal shunt flow through the septal defect. METHODS: Serial two-dimensional echocardiographic diagnosis of the coexistence of VSD and subaortic ridge was done prospectively in 271 patients. The VSD was morphologically characterized as perimembranous, muscular, or subarterial according to the components of its borders. Also, defect size of the VSD was characterized. The presence of septal malalignment was established when the outlet septum was deviated anteriorly or posteriorly. The subaortic ridge was recognized when an echo-bright localized protusion into the left ventricular outflow tract extending from the margin of the septal defect. RESULTS: The prevalence of a subaortic ridge was 8.86% (24/271). The mean age of patients at the initial detection of a subaortic ridge was 11.3+/-9.8 months. Among the 24 patients with a subaortic ridge 14 patients (p<0.01) had more than moderate defect in size of VSD. 16 patients (16/24) had malalignment VSD (p<0.01). A subaortic ridge was found in 20 (9.9%) patients with perimembranous VSD, 4 (8.3%) with subarterial VSD. CONCLUSIONS: The presence of a subaortic ridge associated with a VSD is related to a more than moderate sized defect and/or a malaligned ventricular septum. It is possible that the increased turbulence adjustance to the area of the VSD could favor the development of an abnormal fibrous tissue below the aortic valve.
Aortic Valve ; Diagnosis ; Echocardiography* ; Heart Septal Defects, Ventricular* ; Humans ; Prevalence ; Ventricular Septum

BACKGROUND: The expression of adhesion molecules contribute to development of systemic diseases. Vascular cell adhesion molecule-l(VCAM-1) is an endothelial cell membrane glycoprotein that has been implicated in leukocyte/endothelial cell interactions in inflammation. OBJECTIVE: The aim of this study was to characterize the surface expression and regulation of VCAM-1 on two different endothelial cells. METHOD: We examined the effects of the expression of VCAM-1 in two different endothelial cells, isolated from human umbilical cords and human glomerulus. Expression of VCAM-1 was measured by enzyme-linked immunosorbent assay(ELISA) and flow cytometry. RESULTS: In human umbilical cord endothelial cells(HUVECs), both interleukin-l B(IL-lB) and tumor necrosis factor-a (TNF-a) increased VCAM-1 expression. VCAM-1 expression increased by TNF-a was higher than that increased by IL-lB. In human glomerular endothelial cells(HGECs), IL-lB and TNF-a markedly increased VCAM-1 expression. Conclusion. The regulation of VCAM-1 appears to be somewhat different in HGECs compared with HUVECs. These differences between the responsiveness of the two cells may possibly indicate inherent differences in endothelial cell derived from different vascular beds.
Cell Adhesion ; Cell Communication ; Cytokines* ; Endothelial Cells* ; Flow Cytometry ; Humans* ; Inflammation ; Membrane Glycoproteins ; Necrosis ; Umbilical Cord ; Vascular Cell Adhesion Molecule-1*

BACKGROUND: Recently, childhood obesity has been increasing steeply. Many obese children have complications and high risks to become obese as adults. Therefore, we performed this study to assess childhood obesity in Kwangju area. METHODS: We examined 11,039 children(boys:5,547, girls:5,492) of ages 6-12 years. We defined obesity as more than 97th percentile of weight at each height. We also examined the degree of obesity by comparing with stsndard weight, which is defined as more than 20% above the standard weight for height. We identified four groups according to the degree of obeiity. The ranges for each group was as follows : obesity at from 20% above the standard weight for height, mild obesity at 30% below and 20% above the standard weight for height, and moderate obesity at 50% below and 30% above the standard weight for height, and severe obesity at 50% above the standard weight for height. RESULTS: The prevalence of obesity that exceeded the weight centiles at each height by more than 97th pereentile was 12.17%. The prevalence of obesity that exceeded the standard weight for height by more than 20% was 13.31%. Among them, 8.02/o were mild obesity, 4.44% were moderate obesity and 0. 84% were severe obesity. CONCLUSIONS: Recently, the frequency of childhood obesity goes high in our society. We now know that obesity is a risk factor for some diseases, and therefore, more effective approaches should be developed treat and prevent childhood obesity.
Adult ; Child* ; Gwangju* ; Humans ; Obesity* ; Obesity, Morbid ; Pediatric Obesity ; Prevalence* ; Risk Factors

OBJECTIVES: The purposes of this study were 1) to correlate the carotid intima-medial thickness (IMT) with risk factors of atherosclerosis, 2) to demonstrate the standarized methods of B-mode ultrasound (US) scanning of carotid artery and IMT measurement. MATERIALS AND METHODS: Bilateral carotid arteries of 95 adult volunteers were scanned using 12 MHz linear probe. The mean of bilateral IMT was regarded as the volunteer's IMT, which was measured on the far wall of distal common carotid artery. The normality test for measured IMT and correlation tests between IMT and various known risk factors of atherosclerosis including age, end-systolic blood pressure, end-diastolic blood pressure, fasting blood glucose level, body mass index, life-style data and lipid profiles were performed. Inter-observer and intra-observer variability were evaluated through correlation tests on 20 randomly sampled data. RESULTS: The measured IMT showed normal distribution (mean=0.673 mm, SD=+/-0.1, p=0.494) and the 95th percentile was 0.830 mm. The systolic blood pressure (r=0.101) and body mass index (r=0.200) showed positive correlation but they did not show statistically significant relationships with IMT (p>0.05). The age showed statistically significant correlation (r=0.585, p<0.001), but the other risk factors did not show statistically significant correlation with IMT. The correlation coefficients of inter-observer and intra-observer variability on IMT measurement were 0.8770 and 0.9213, respectively. CONCLUSION: The diagnostic criteria for early carotid atherosclerosis using B-mode US could be estimated from our data. Our measurement protocols showed high reproducibility. The associations between most risk factors that did not show statistically significant correlation in our study and IMT should be confirmed in a population-based study.
Adult* ; Atherosclerosis ; Blood Glucose ; Blood Pressure ; Body Mass Index ; Carotid Arteries* ; Carotid Artery Diseases ; Carotid Artery, Common ; Fasting ; Humans ; Observer Variation ; Risk Factors ; Ultrasonics ; Ultrasonography* ; Volunteers*