1.Basic Study on the Effect of Korean Ginseng upon Fracture Healing of the Bone
Han Koo LEE ; Moon Sang CHUNG ; Gang Sup YOON
The Journal of the Korean Orthopaedic Association 1984;19(3):483-491
This study was planned by the necessities of basic information about the effects of Korean Ginseng upon fracture healing and biomechanical properties of bone. Three hundred white mice were used for this study, and we could have tested the biomechanical properties in one hundred and nintyfour. The bones of the white mice were evaluated by testing gross stability, radiological appearance, and biomechanical properties. It appears that Korean Ginseng has an excellent effect upon early phase of fracture healing of the bone. The summary of this study are as follows: 1. With near maximal dose, Korean Ginseng showed very excellent effect upon early phase of the fracture healing. 2. There was no apparent effect on remodeling phase of the fracture healing with Korean Ginseng of near maximal dose. 3. Korean Ginseng appeared to have no effect on fracture healing with minimal dose. 4. Upon biomechanical properties of the bone, Korean Ginseng was seemed to be effective with near maximal dose. But, there was no definite evidence for that.
Animals
;
Fracture Healing
;
Mice
;
Panax
2.Survival Prediction of Ganglio-thalamic Hemorrhage Accompanying Intraventricular Hemorrhage Using CT Scan Indices.
Moon Gang HAN ; Jin Sang JUNG ; Jae Moon KIM ; Bong Ae WIE
Journal of the Korean Neurological Association 1990;8(1):29-34
To develop a survival prediction model and to use it as a therapeutic guideline a series of 66 cases with ganglio-thalamic hemorrhage accompanying intraventricular hemorrhage were analyzed retrospectively. They were classified into the benign and fatal groups according to their final outcomes. Fourteen indices obtained from the initial CT scans were final outcomes. Fourteen indices obtained from the initial CT scans were subjected to multivariate discriminant analysis. The resultant discriminant function(Z) included the amount of hematoma in the parenchyme(AH), bicaudate cerebroventricular index(BCCI) maximum fourth ventricular width(FVW), and third cerebroventricular ratio(TCR) in an order of decreasing discriminating power and was as follows: Z = -3.2639 + 0.3508 X 10(-1) X AH + 6.8816 X BCCI + 0.1139 X FVW-5.7794 X TCR. This function predicted survivability with accuracy of 84.9% when it was applied to the original subjects. The conclusion is that AH, BCCI, FVW, and TCR are the potent predictors of the survival of patients with ganglio-thalamic hemorrhage accompanying intraventricular hemorrhage.
Hematoma
;
Hemorrhage*
;
Humans
;
Retrospective Studies
;
Tomography, X-Ray Computed*
3.Posterior Tarsal Tunnel Syndrome Caused by a Ganglion.
Moon Gang HAN ; Kwang Won LEE ; Mi Ja PARK
Journal of the Korean Neurological Association 1992;10(1):109-112
Tarsal tunnel syndrome is relatively an uncommon and usually under-recognized or misdiagnosed condition. We report a case of posterior tarsal tunnel syndrome caused by a ganglion . A 58-year-old woman complained of burning and tingling sensation along the left sole and presented weakness, muscle atrophy, and Tinel's sign in the left foot. Electrodiagnostic study revealed prolonged terminal latency, reduced compound muscle action potential, absent sensory nelve potential, and denervation potentials. After removal of the ganglion, patient's symptoms improved and the electrodiagnostic study performed after two months showed significant improvement.
Action Potentials
;
Atrophy
;
Burns
;
Denervation
;
Female
;
Foot
;
Ganglion Cysts*
;
Humans
;
Middle Aged
;
Muscle Weakness
;
Sensation
;
Tarsal Tunnel Syndrome*
4.A case of polyneuropathy associated with folic acid deficiency.
Seung Han YANG ; Jeong Lim MOON ; Gang AEO ; Sung Hun NAM
Journal of the Korean Academy of Rehabilitation Medicine 1992;16(3):317-322
No abstract available.
Folic Acid Deficiency*
;
Folic Acid*
;
Polyneuropathies*
5.Clinical and CT Characteristics of SAH with no Aneurysm Visualized on the First Angiogram.
Chin Sang CHUNG ; Moon Gang HAN ; Jei KIM ; Bong Ae WIE
Journal of the Korean Neurological Association 1990;8(2):212-219
A retrospective study was performed to provide the clinical and radiological grounds for decision-making as to whether the next cerebral angiography is to be followed when no aneurysm is revealed on the first procedure in patients with spontaneous subarachnoid hemorrhage. Thc clinical courses of 22 patients who showed no aneurysm on their first angiogram(unproven group) were compared with those of 19 patients of the similar clinical status whose aneurgsm(s) was/were proven but not operated(non-operated group). The results were: 1)The incidences of vasospasm, hydrocephalus, electrolyte disturbances, infections, and gastrointestinal bleeding were similar between the groups; 2)Rebleeding was Iess frequent in thc unproven group(p<.05); 3) Neurological outcomes were also significantly beffer in the unproven group(p<.018; 4) The distributions of blood clots in the subarachnoid space were less predictive of aneurysmal site in the unproven group. Considering thc better prognosis and the nonspecific CT findings of the unproven group, our results suggest that when no aneurysm is demonstrated on the first angiogram, the repeated angiography may not be necessary.
Aneurysm*
;
Angiography
;
Cerebral Angiography
;
Dronabinol
;
Hemorrhage
;
Humans
;
Hydrocephalus
;
Incidence
;
Prognosis
;
Retrospective Studies
;
Subarachnoid Hemorrhage
;
Subarachnoid Space
6.Serum Lipids in the Patients with Cerebral Thrombosis.
Bong Ae WIE ; Moon Gang HAN ; Jong Hoon JEON ; Min Ja YIM ; Chin sang CHUNG
Journal of the Korean Neurological Association 1989;7(2):258-265
To evaluate the role of serum lipids in the patients with cerebral thrombosis, lipid parameters were compared with a sex- and age - matched healthy control. The cerebral thrombosis group included 61 males (mean age, 61.0) and 32 females (mean age, 66.3). Total cholesterol and total/HDL-cholesterol ratio in the male and female patients were significantly higher than in the control(p<0.001). But triglyceride showed difference only in the male patient group (p<0.05). All parameters did not show any difference between the lacunar and cortical infarctions. The finding in this study support the idea that high serum total cholesterol, low serum HDL-cholesterol and high total / HDL-cholesterol ratio are risk factors for cerebral thrombosis.
Cholesterol
;
Female
;
Humans
;
Infarction
;
Intracranial Thrombosis*
;
Male
;
Risk Factors
;
Triglycerides
7.Dyke-Davidoff-Masson Syndrome Associated with Occlusion of Internal Carotid Artery.
Chin Sang CHUNG ; Moon Gang HAN ; Jong Hoon JEON ; Cheong Hee PARK ; Byung Chull RHEE ; Bong Ae WIE
Journal of the Korean Neurological Association 1990;8(1):192-197
No abstract available.
Carotid Artery, Internal*
8.A Bilateral Blindness following the General Anesthesia .
Sung Baik KOH ; Tae Suk KIM ; II Hyun RO ; Yung Sam MOON
Korean Journal of Anesthesiology 1980;13(3):300-302
Postoperative total blindness was seen in a 48 year old male who had a laparotomy for traumatic perforation of intestine. General inhalation anesthesia of ether-oxygen-mask with semiclosed system was applied after initial ketamine administration. This unhappy ocular complication could be occur secondary to excessive prolonged external compression to eyeballs with mask or/and prolonged postoperative hypotension.
Anesthesia, General*
;
Anesthesia, Inhalation
;
Blindness*
;
Humans
;
Hypotension
;
Intestines
;
Ketamine
;
Laparotomy
;
Male
;
Masks
9.Application of Pulsed Radiofrequency to Intractable Neuropathic Pain.
Mi Sook GANG ; Soung Moon HAN ; Young Jin LIM ; Sang Chul LEE
Korean Journal of Anesthesiology 2000;39(2):293-295
For several decades, Radiofrequency lesioning has been used for intractable pain that originates from the spinal area. Heating of the tissue has been assumed to be the only mechanism that can cause this effect. There has never been the suggestion that the RF fields themselves can modify the neuro-cellular function independently of the thermal effect. Additionally, Radiofrequency machines can not be used in neuropathic pain because of their thermal effect. Recently, a modified type of Radiofrequency machine was developed, using a non-thermal pulse, and applying a relatively high voltage. Some authors have reported remarkable results using this technique recently. There are several possible mechanisms and several attempts have been tried to explain this therapeutic effect respectively, but none of them explain it fully. One possible mechanism is through an Electro-Magnetic Field (EMF) that doesn't produce high temperature in the tip area. This is done in a pulsed fashion to avoid the high temperature made during the active cycle. However there is no apparent mechanism that explains this therapeutic effect clearly. The patient whom we report now was a 23 year-old male who suffered from repetitive low back pain and radiculopathy. He failed to respond to other oral and invasive conventional therapies. We experienced a successful result in the treatment of his intractable neuropathic pain using this pulsed RF machine.
Heating
;
Hot Temperature
;
Humans
;
Low Back Pain
;
Male
;
Neuralgia*
;
Pain, Intractable
;
Radiculopathy
;
Young Adult
10.A Case of Acute Alcoholic Myopathy with Paraparesis and Myoglobinuric Renal Failure.
Moon Gang HAN ; Byeung Seok CHO ; Seong Kyu PARK ; Chan Geun PARK ; Sang Hyun BAIK
Journal of the Korean Neurological Association 1993;11(2):277-280
Acute alcoholic myopathy presented with paraparesis, myoglobinuria. And acute renal failure is an uncommon complication of alcoholism. A 34-year-old man had been a heavy alcohol drinker for a year, complained of sudden lower extremity weal; ness and swelling after heavy drinking. On examination, lower extremity was swollen and unable to move. Laboratory data showed markedly elevated GOT, LDH, CK, and myoglobinuria. Initial electrodiagnostic study was indefinite for diagnosis of myopathy and biopsy of the quadriceps muscle showed slight increased eosinophilia of sarcoplasm. But in followup study, myopathic findings and degeneration becarne apparent in electromyography and blopsy.
Acute Kidney Injury
;
Adult
;
Alcoholics*
;
Alcoholism
;
Biopsy
;
Diagnosis
;
Drinking
;
Electromyography
;
Eosinophilia
;
Follow-Up Studies
;
Humans
;
Lower Extremity
;
Muscular Diseases*
;
Myoglobinuria
;
Paraparesis*
;
Quadriceps Muscle
;
Renal Insufficiency*