1.Association of Dietary Quality Indices with Glycemic Status in Korean Patients with Type 2 Diabetes.
Jiyoung KIM ; Youngyun CHO ; Youngmi PARK ; Cheongmin SOHN ; Miyong RHA ; Moon Kyu LEE ; Hak C JANG
Clinical Nutrition Research 2013;2(2):100-106
The present study was performed to evaluate the relationship between dietary quality indices including the Diet Quality Index-International (DQI-I), Alternate Healthy Eating Index (AHEI), and Healthy Diet Indicator (HDI) and glycemic status in Korean patients with type 2 diabetes. A total of 110 consecutive outpatients with type 2 diabetes who visited 2 university hospitals in Seoul and Seongnam from April 2004 to November 2006 were enrolled as subjects. At the time of enrollment, anthropometric parameters, dietary habits, experience of exercise, and metabolic parameters were obtained. Experienced registered dietitians collected one-day dietary intake using the 24-hour recall method. The mean scores for DQI-I, AHEI, and HDI were 68.9 +/- 8.2, 39.4 +/- 8.9, and 5.0 +/- 1.3, respectively. After adjustment for age, body mass index, and energy intake, DQI-I and HDI were found to have a significant correlation with hemoglobin A1c (HbA1c) (r = -0.21, p < 0.05; r = -0.28, p < 0.05), fasting plasma glucose (r = -0.21, p < 0.05; r = -0.23, p < 0.05), and postprandial 2-h glucose (r = -0.30, p < 0.05; r = -0.26, p < 0.05, respectively). However, AHEI did not have a significant correlation with HbA1c. In conclusion, the DQI-I and HDI may be useful tools in assessing diet quality and adherence to dietary recommendations in Korean patients with type 2 diabetes. Future research is required to determine whether the dietary quality indices have predictive validity for dietary and glycemic changes following diet education in a clinical setting.
Blood Glucose
;
Body Mass Index
;
Diabetes Mellitus
;
Diet
;
Diet Therapy
;
Eating
;
Education
;
Energy Intake
;
Fasting
;
Food Habits
;
Glucose
;
Glycemic Index
;
Gyeonggi-do
;
Hospitals, University
;
Humans
;
Nutritionists
;
Outpatients
;
Seoul
2.Pseudotumor and Subsequent Implant Loosening as a Complication of Revision Total Hip Arthroplasty with Ceramic-on-Metal Bearing: A Case Report
Lokesh Gudda NAIK ; Won Yong SHON ; I C CLARKE ; Jun Gyu MOON ; Piyush MUKUND ; Sang Min KIM
Hip & Pelvis 2018;30(4):276-281
Pseudotumors are not uncommon complications after total hip arthroplasty (THA) and may occur due to differences in bearing surfaces of the head and the liner ranging from soft to hard articulation. The most common causes of pseudotumors are foreign-body reaction, hypersensitivity and wear debris. The spectrum of pseudotumor presentation following THA varies greatly-from completely asymptomatic to clear implant failure. We report a case of pseudo-tumor formation with acetabular cup aseptic loosening after revision ceramic-on-metal hip arthroplasty. The patient described herein underwent pseudotumor excision and re-revision complex arthroplasty using a trabecular metal shell and buttress with ceramic-on-polyethylene THA. Surgeons should be aware of the possibility of a pseudotumor when dealing with revisions to help prevent rapid progression of cup loosening and implant failure, and should intervene early to avoid complex arthroplasty procedures.
Acetabulum
;
Arthroplasty
;
Arthroplasty, Replacement, Hip
;
Foreign-Body Reaction
;
Head
;
Hip
;
Humans
;
Hypersensitivity
;
Surgeons
3.Reduced Mortality by Physician-Staffed HEMS Dispatch for Adult Blunt Trauma Patients in Korea.
Kyoungwon JUNG ; Yo HUH ; John C J LEE ; Younghwan KIM ; Jonghwan MOON ; Seok Hwa YOUN ; Jiyoung KIM ; Tea Youn KIM ; Juryang KIM ; Hyoju KIM
Journal of Korean Medical Science 2016;31(10):1656-1661
The aim of this study was to investigate the efficiency of domestic physician-staffed helicopter emergency medical service (HEMS) for the transport of patients with severe trauma to a hospital. The study included patients with blunt trauma who were transported to our hospital by physician-staffed HEMS (Group P; n = 100) or nonphysician-staffed HEMS (Group NP; n = 80). Basic patient characteristics, transport time, treatment procedures, and medical treatment outcomes assessed using the Trauma and Injury Severity Score (TRISS) were compared between groups. We also assessed patients who were transported to the hospital within 3 h of injury in Groups P (Group P3; n = 50) and NP (Group NP3; n = 74). The severity of injury was higher, transport time was longer, and time from hospital arrival to operation room transfer was shorter for Group P than for Group NP (P < 0.001). Although Group P patients exhibited better medical treatment outcomes compared with Group NP, the difference was not statistically significant (P = 0.134 vs. 0.730). However, the difference in outcomes was statistically significant between Groups P3 and NP3 (P = 0.035 vs. 0.546). Under the current domestic trauma patient transport system in South Korea, physician-staffed HEMS are expected to increase the survival of patients with severe trauma. In particular, better treatment outcomes are expected if dedicated trauma resuscitation teams actively intervene in the medical treatment process from the transport stage and if patients are transported to a hospital to receive definitive care within 3 hours of injury.
Adult*
;
Aircraft
;
Emergencies
;
Emergency Medical Services
;
Humans
;
Injury Severity Score
;
Korea*
;
Mortality*
;
Resuscitation
;
Trauma Centers
;
Treatment Outcome
4.Pregnancy Outcomes of Women Additionally Diagnosed as Gestational Diabetes by the International Association of the Diabetes and Pregnancy Study Groups Criteria
Min Hyoung KIM ; Soo Heon KWAK ; Sung Hoon KIM ; Joon Seok HONG ; Hye Rim CHUNG ; Sung Hee CHOI ; Moon Young KIM ; Hak C JANG
Diabetes & Metabolism Journal 2019;43(6):766-775
BACKGROUND: We investigated the pregnancy outcomes in women who were diagnosed with gestational diabetes mellitus (GDM) by the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria but not by the Carpenter-Coustan (CC) criteria.METHODS: A total of 8,735 Korean pregnant women were identified at two hospitals between 2014 and 2016. Among them, 2,038 women participated in the prospective cohort to investigate pregnancy outcomes. Diagnosis of GDM was made via two-step approach with 50-g glucose challenge test for screening followed by diagnostic 2-hour 75-g oral glucose tolerance test. Women were divided into three groups: non-GDM, GDM diagnosed exclusively by the IADPSG criteria, and GDM diagnosed by the CC criteria.RESULTS: The incidence of GDM was 2.1% according to the CC criteria, and 4.1% by the IADPSG criteria. Women diagnosed with GDM by the IADPSG criteria had a higher body mass index (22.0±3.1 kg/m² vs. 21.0±2.8 kg/m², P<0.001) and an increased risk of preeclampsia (odds ratio [OR], 6.90; 95% confidence interval [CI], 1.84 to 25.87; P=0.004) compared to non-GDM women. Compared to neonates of the non-GDM group, those of the IADPSG GDM group had an increased risk of being large for gestational age (OR, 2.39; 95% CI, 1.50 to 3.81; P<0.001), macrosomia (OR, 2.53; 95% CI, 1.26 to 5.10; P=0.009), and neonatal hypoglycemia (OR, 3.84; 95% CI, 1.01 to 14.74; P=0.049); they were also at an increased risk of requiring phototherapy (OR, 1.57; 95% CI, 1.07 to 2.31; P=0.022) compared to the non-GDM group.CONCLUSION: The IADPSG criteria increased the incidence of GDM by nearly three-fold, and women diagnosed with GDM by the IADPSG criteria had an increased risk of adverse pregnancy outcomes in Korea.
Body Mass Index
;
Cohort Studies
;
Diabetes, Gestational
;
Diagnosis
;
Female
;
Gestational Age
;
Glucose
;
Glucose Tolerance Test
;
Humans
;
Hypoglycemia
;
Incidence
;
Infant, Newborn
;
Korea
;
Mass Screening
;
Phototherapy
;
Pre-Eclampsia
;
Pregnancy
;
Pregnancy Outcome
;
Pregnancy
;
Pregnant Women
;
Prospective Studies
5.Clinical Report of 46 Intracranial Tumors with LINAC Based Stereotactic Radiosurgery.
Sei C YOON ; Tae S SUH ; Sung W KIM ; Ki M KANG ; Yun S KIM ; Byung O CHOI ; Hong S JANG ; Kyo H CHOI ; Moon C KIM ; Kyung S SHINN
Journal of the Korean Society for Therapeutic Radiology 1993;11(2):241-248
Between July 1988 and December 1992, we treated 45 patients who had deep seated inoperable or residual and/or recurrent intracranial tumors using LINAC based stereotactic radiosurgery at the Department of Therapeutic Radiology, Kangnam St. Mary's Hospital, Catholic University Medical College. Treated intracranial tumors included pituitary tumors(n=15), acoustic neurinomas(n=8), meningiomas(n=7), gliomas(n=6), craniopharyngiomas(n=4), pinealomas(n=3), hemangioblastomas(n=2), and solitary metastatic tumor from lung cancer (n=1). The dimension of treatment field varied from 0.23 to 42.88 cm3(mean ; 7.26 cm3). The maximum tumor doses ranging from 5 to 35.5 Gy (mean; 29.9 Gy) were given, and depended on patients' age, target volume, location of lesion and previous history of irradiation. There were 22 male and 23 female patients. The age was varied from 5 to 74 years of age(a median age; 43 years). The mean duration of follow-up was 35 months (2~55 months). To date, 18(35.1%) of 46 intracranial tumors treated with SRS showed absent or decrease of the tumor by serial follow-up CT and/or MRI and 16(34.8%) were stationary, e.g. growth arrest. From the view point of the clinical aspects, 34(73.9%) of 46 tumors were considered improved status, that is, alive with no evidence of active tumor and 8(17.4%) of them were stable, alive with disease but no deterioration as compared with before SRS. Although there showed slight increase of the tumor in size according to follow-up imagings of 4 cases(pituitary tumor 1, acoustic neurinomas 2, pinealoma 1), they still represented clinically stable status. Clinically, two(4.4%) patients who were anaplastic astrocytoma(n=1) and metastatic brain tumor(n=1) were worsened following SRS treatment. So far, no serious complications were found after treatment. The minor degree headache which could be relieved by steroid or analgesics and transient focal hair loss were observed in a few cases. There should be meticulous long term follow-up in all cases.
Acoustics
;
Analgesics
;
Brain
;
Craniopharyngioma
;
Female
;
Follow-Up Studies
;
Glioma
;
Hair
;
Headache
;
Hemangioblastoma
;
Humans
;
Lung Neoplasms
;
Magnetic Resonance Imaging
;
Male
;
Meningioma
;
Neuroma, Acoustic
;
Pinealoma
;
Pituitary Neoplasms
;
Radiation Oncology
;
Radiosurgery*
6.Effective Transport for Trauma Patients under Current Circumstances in Korea: A Single Institution Analysis of Treatment Outcomes for Trauma Patients Transported via the Domestic 119 Service.
Jiyoung KIM ; Yunjung HEO ; John C J LEE ; Sukja BAEK ; Younghwan KIM ; Jonghwan MOON ; Seok Hwa YOUN ; Heejung WANG ; Yo HUH ; Kyoungwon JUNG
Journal of Korean Medical Science 2015;30(3):336-342
In Korea, which still lacks a well-established trauma care system, the inability to transport patients to adequate treatment sites in a timely manner is a cause of low trauma patient survival. As such, this study was conducted to serve as a basis for the establishment of a future trauma transport system. We performed a comparative analysis of the transport time, and treatment outcomes between trauma victims transported by ground ambulance (GAMB) and those transported via the helicopter emergency medical service (HEMS) through the National Emergency Management Agency's 119 reporting system, which is similar to the 911 system of the United States, from March 2011 to May 2014. The HEMS-transported patients received treatment instructions, by remote communication, from our trauma specialists from the time of accident reporting; in certain instances, members of the trauma medical staff provided treatment at the scene. A total of 1,626 patients were included in the study; the GAMB and HEMS groups had 1,547 and 79 patients, respectively. The median transport time was different between 2 groups (HEMS, 60 min vs. GAMB, 47 min, P<0.001) but for all patients was 49 min (less than the golden hour). Outcomes were significantly better in the HEMS compared to the GAMB, using the trauma and injury severity score (survival rate, 94.9% vs. 90.5%; Z score, 2.83 vs. -1.96; W score, 6.7 vs. -0.8). A unified 119 service transport system, which includes helicopter transport, and the adoption of a trauma care system that allows active initial involvement of trauma medical personnel, could improve the treatment outcome of trauma patients.
Air Ambulances/*utilization
;
Emergency Service, Hospital/*statistics & numerical data
;
Female
;
Humans
;
Injury Severity Score
;
Male
;
Prognosis
;
Republic of Korea
;
Survival Rate
;
Time Factors
;
Trauma Centers
;
Treatment Outcome
;
Wounds, Nonpenetrating/*mortality/therapy
;
Wounds, Penetrating/*mortality/therapy
7.Effective Transport for Trauma Patients under Current Circumstances in Korea: A Single Institution Analysis of Treatment Outcomes for Trauma Patients Transported via the Domestic 119 Service.
Jiyoung KIM ; Yunjung HEO ; John C J LEE ; Sukja BAEK ; Younghwan KIM ; Jonghwan MOON ; Seok Hwa YOUN ; Heejung WANG ; Yo HUH ; Kyoungwon JUNG
Journal of Korean Medical Science 2015;30(3):336-342
In Korea, which still lacks a well-established trauma care system, the inability to transport patients to adequate treatment sites in a timely manner is a cause of low trauma patient survival. As such, this study was conducted to serve as a basis for the establishment of a future trauma transport system. We performed a comparative analysis of the transport time, and treatment outcomes between trauma victims transported by ground ambulance (GAMB) and those transported via the helicopter emergency medical service (HEMS) through the National Emergency Management Agency's 119 reporting system, which is similar to the 911 system of the United States, from March 2011 to May 2014. The HEMS-transported patients received treatment instructions, by remote communication, from our trauma specialists from the time of accident reporting; in certain instances, members of the trauma medical staff provided treatment at the scene. A total of 1,626 patients were included in the study; the GAMB and HEMS groups had 1,547 and 79 patients, respectively. The median transport time was different between 2 groups (HEMS, 60 min vs. GAMB, 47 min, P<0.001) but for all patients was 49 min (less than the golden hour). Outcomes were significantly better in the HEMS compared to the GAMB, using the trauma and injury severity score (survival rate, 94.9% vs. 90.5%; Z score, 2.83 vs. -1.96; W score, 6.7 vs. -0.8). A unified 119 service transport system, which includes helicopter transport, and the adoption of a trauma care system that allows active initial involvement of trauma medical personnel, could improve the treatment outcome of trauma patients.
Air Ambulances/*utilization
;
Emergency Service, Hospital/*statistics & numerical data
;
Female
;
Humans
;
Injury Severity Score
;
Male
;
Prognosis
;
Republic of Korea
;
Survival Rate
;
Time Factors
;
Trauma Centers
;
Treatment Outcome
;
Wounds, Nonpenetrating/*mortality/therapy
;
Wounds, Penetrating/*mortality/therapy
8.Progression to Gestational Diabetes Mellitus in Pregnant Women with One Abnormal Value in Repeated Oral Glucose Tolerance Tests
Sunyoung KANG ; Min Hyoung KIM ; Moon Young KIM ; Joon Seok HONG ; Soo Heon KWAK ; Sung Hee CHOI ; Soo LIM ; Kyong Soo PARK ; Hak C JANG
Diabetes & Metabolism Journal 2019;43(5):607-614
BACKGROUND: Women with one abnormal value (OAV) in a 100 g oral glucose tolerance test (OGTT) during pregnancy are reported to have an increased risk of adverse pregnancy outcomes. However, there is limited data about whether women with OAV will progress to gestational diabetes mellitus (GDM) when the OGTT is repeated. METHODS: To identify clinical and metabolic predictors for GDM in women with OAV, we conducted a retrospective study and identified women with OAV in the OGTT done at 24 to 30 weeks gestational age (GA) and repeated the second OGTT between 32 and 34 weeks of GA. RESULTS: Among 137 women with OAV in the initial OGTT, 58 (42.3%) had normal, 40 (29.2%) had OAV and 39 (28.5%) had GDM in the second OGTT. Maternal age, prepregnancy body mass index, weight gain from prepregnancy to the second OGTT, GA at the time of the OGTT, and parity were similar among normal, OAV, and GDM groups. Plasma glucose levels in screening tests were different (151.8±15.7, 155.8±14.6, 162.5±20.3 mg/dL, P<0.05), but fasting, 1-, 2-, and 3-hour glucose levels in the initial OGTT were not. Compared to women with screen negative, women with untreated OAV had a higher frequency of macrosomia. CONCLUSION: We demonstrated that women with OAV in the initial OGTT significantly progressed to GDM in the second OGTT. Clinical parameters predicting progression to GDM were not found. Repeating the OGTT in women with OAV in the initial test may be helpful to detect GDM progression.
Blood Glucose
;
Body Mass Index
;
Diabetes, Gestational
;
Fasting
;
Female
;
Gestational Age
;
Glucose
;
Glucose Tolerance Test
;
Humans
;
Mass Screening
;
Maternal Age
;
Parity
;
Pregnancy
;
Pregnancy Outcome
;
Pregnant Women
;
Retrospective Studies
;
Weight Gain
9.Machine learning based potentiating impacts of 12‑lead ECG for classifying paroxysmal versus non‑paroxysmal atrial fibrillation
Sungsoo KIM ; Sohee KWON ; Mia K. MARKEY ; Alan C. BOVIK ; Sung‑Hwi HONG ; JunYong KIM ; Hye Jin HWANG ; Boyoung JOUNG ; Hui‑Nam PAK ; Moon‑Hyeong LEE ; Junbeom PARK
International Journal of Arrhythmia 2022;23(2):11-
Background:
Conventional modality requires several days observation by Holter monitor to differentiate atrial fibril‑ lation (AF) between Paroxysmal atrial fibrillation (PAF) and Non-paroxysmal atrial fibrillation (Non-PAF). Rapid and practical differentiating approach is needed.
Objective:
To develop a machine learning model that observes 10-s of standard 12-lead electrocardiograph (ECG) for real-time classification of AF between PAF versus Non-PAF.
Methods:
In this multicenter, retrospective cohort study, the model training and cross-validation was performed on a dataset consisting of 741 patients enrolled from Severance Hospital, South Korea. For cross-institutional validation, the trained model was applied to an independent data set of 600 patients enrolled from Ewha University Hospital, South Korea. Lasso regression was applied to develop the model.
Results:
In the primary analysis, the Area Under the Receiver Operating Characteristic Curve (AUC) on the test set for the model that predicted AF subtype only using ECG was 0.72 (95% CI 0.65–0.80). In the secondary analysis, AUC only using baseline characteristics was 0.53 (95% CI 0.45–0.61), while the model that employed both baseline characteris‑ tics and ECG parameters was 0.72 (95% CI 0.65–0.80). Moreover, the model that incorporated baseline characteristics, ECG, and Echocardiographic parameters achieved an AUC of 0.76 (95% CI 0.678–0.855) on the test set.
Conclusions
Our machine learning model using ECG has potential for automatic differentiation of AF between PAF versus Non-PAF achieving high accuracy. The inclusion of Echocardiographic parameters further increases model per‑ formance. Further studies are needed to clarify the next steps towards clinical translation of the proposed algorithm.
10.Classification and Surgical Treatment of Paraclinoid Aneurysms.
Moon Jun SOHN ; Chae Heuck LEE ; Young Shin RA ; Chang Jin KIM ; Yang KWON ; Seung Chul RHIM ; Jung Kyo LEE ; Byung Duk KWUN ; C Jin WHANG
Journal of Korean Neurosurgical Society 1996;25(9):1828-1839
Paraclinoid aneurysms arose from the proximal internal carotid artery between the site of emergence of carotid artery from the roof of the cavernous sinus and posterior communicating artery. Surgery of these aneurysms presents special difficulties because of its complicated osseous, dura, and neurovascular structures;sella turcica, cavernous sinus, optic nerve. The clinical and radiological characteristics in twenty-seven patients with the paraclinoid aneurysms were reviewed and classified into four subgroups according to their branch of origin in this segment;1) carotid cave aneurysm(2 cases), 2) ophthalmic artery aneurysm(11 cases), 3) superior hypophyseal artery aneurysm(11 cases), 4) proximal posterior carotid artery wall aneurysm or global type aneurysm(3 cases). Surgery required orbital unroofing and removal of anterior clinid process with release of dural ring. To provide easy proximal control, exposure of cervical carotid artery was helpful in some cases. Preoperative balloon occlusion testing was man datory. Outcomes were considered as good to fair in 19 patients, poor in five, and three patients died. The patients who had poor results were poor preoperative status-four were grade IV, one was grade II(Hunt-Hess grade). The causes of death were premature rupture(2 cases) and extensive vasospasm(1 case). Preoperative classification of these lesions provides excellent correlation of operative findings and surgical preparation to expose the proximal part of internal carotid artery.
Aneurysm*
;
Arteries
;
Balloon Occlusion
;
Carotid Arteries
;
Carotid Artery, Internal
;
Cause of Death
;
Cavernous Sinus
;
Classification*
;
Humans
;
Ophthalmic Artery
;
Optic Nerve
;
Orbit