1.Clinical and Mycological Study of Tinea Faciale.
Moo Woong LEE ; Jong Soo CHOI ; Ki Hong KIM
Korean Journal of Dermatology 1994;32(4):662-668
BACKGROUND: Tinea faciale usually has been classified as tinea corgoris. Recently it has often been classified as a seperate disease recently because of its various clinicel pesentations. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycological findings of tinea faciale, METHODS: Clinieal and mycological study was done with 42 eases of tinea faciale among out-patients examined for eight years from January 1985 to December 1992 at Yeungnam University Hospital, Taegu, Korea. RESULTS & CONCLUSION: 1. The average of annual distribution of patients was five and there a as no significant difference according to year. The age distribution of patients was highest under age 10(33.4%). The ratio of male to female patient was 3.1: 1. Monthly or seasonal distribution if patients was not significantly different. 2. Of 42 cases, causative organisms were isolated in 31 cases. They are Trichophyton(T.) rubrum in 19 cases (61.3%), Microsporum(M.) canis in 6 cases (19.4%), T. mentcgrophytes in 5 cases (16.1%) and M. gypseum in 1 case(3.7%) in tbe order of decreasing frequncd M. canis was the main causative organisrn in children under age 10. In the age group after 10, T. rubrum was predominated. T. rubrum infection was most frequently seen in spring, T. mentagrphates infection was seen more in winter and M. canis infectior in autumn. 3. Classic annular types were seen most frequently in the cases caused by T. rubrum and T. mentagrophytes. Papular types were seen most commonly in the case caused by M. canis. Multiple facial lesions were seen in T. rubrum infection (2 cases) and Of canis infection (1 case). Tinea faciale simulated several other dermatoses. These were contact, dermatitis, lupus erythematosus, photosensitive dermatosis, rosacea, granuloma annulare and acne. Of these, tinea faciale simulated contact dermatitis most frequently. Coexisting fungal infections were found in 7 patients and tinea corporis was most frequently present. Topical antifungsl agent was tried alone in 22 cases, and topical and systemic antifungal agent were combined in 20 cases.
Acne Vulgaris
;
Age Distribution
;
Child
;
Daegu
;
Dermatitis
;
Dermatitis, Contact
;
Female
;
Granuloma Annulare
;
Humans
;
Korea
;
Male
;
Outpatients
;
Rosacea
;
Seasons
;
Skin Diseases
;
Tinea*
2.Clinical and Mycological Study of Tinea Faciale.
Moo Woong LEE ; Jong Soo CHOI ; Ki Hong KIM
Korean Journal of Dermatology 1994;32(4):662-668
BACKGROUND: Tinea faciale usually has been classified as tinea corgoris. Recently it has often been classified as a seperate disease recently because of its various clinicel pesentations. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycological findings of tinea faciale, METHODS: Clinieal and mycological study was done with 42 eases of tinea faciale among out-patients examined for eight years from January 1985 to December 1992 at Yeungnam University Hospital, Taegu, Korea. RESULTS & CONCLUSION: 1. The average of annual distribution of patients was five and there a as no significant difference according to year. The age distribution of patients was highest under age 10(33.4%). The ratio of male to female patient was 3.1: 1. Monthly or seasonal distribution if patients was not significantly different. 2. Of 42 cases, causative organisms were isolated in 31 cases. They are Trichophyton(T.) rubrum in 19 cases (61.3%), Microsporum(M.) canis in 6 cases (19.4%), T. mentcgrophytes in 5 cases (16.1%) and M. gypseum in 1 case(3.7%) in tbe order of decreasing frequncd M. canis was the main causative organisrn in children under age 10. In the age group after 10, T. rubrum was predominated. T. rubrum infection was most frequently seen in spring, T. mentagrphates infection was seen more in winter and M. canis infectior in autumn. 3. Classic annular types were seen most frequently in the cases caused by T. rubrum and T. mentagrophytes. Papular types were seen most commonly in the case caused by M. canis. Multiple facial lesions were seen in T. rubrum infection (2 cases) and Of canis infection (1 case). Tinea faciale simulated several other dermatoses. These were contact, dermatitis, lupus erythematosus, photosensitive dermatosis, rosacea, granuloma annulare and acne. Of these, tinea faciale simulated contact dermatitis most frequently. Coexisting fungal infections were found in 7 patients and tinea corporis was most frequently present. Topical antifungsl agent was tried alone in 22 cases, and topical and systemic antifungal agent were combined in 20 cases.
Acne Vulgaris
;
Age Distribution
;
Child
;
Daegu
;
Dermatitis
;
Dermatitis, Contact
;
Female
;
Granuloma Annulare
;
Humans
;
Korea
;
Male
;
Outpatients
;
Rosacea
;
Seasons
;
Skin Diseases
;
Tinea*
3.A biomechanical study of two methods of internal fixation of fractures of femoral neck.
Kwang Suk LEE ; Moo Kyeong KO ; Jong Woong PARK
The Journal of the Korean Orthopaedic Association 1993;28(3):1140-1152
No abstract available.
Femur Neck*
4.Four cases of cutaneous tuberculosis.
Moo Woong LEE ; Tae Hun KWAK ; Jong Soo CHOI ; Ki Hong KIM ; Mi Jin KIM
Yeungnam University Journal of Medicine 1992;9(1):181-188
The incidence of the cutaneous tuberculosis has shown a steady decline over the past decades. This parallels the decreasing incidence of pulmonary tuberculosis. We experienced 5 cases of cutaneous tuberculosis from January 1990 to February 1991. We present herein 4 cases of cutaneous tuberculosis. They were 3 cases of vulgaris and 1 case of tuberculosis verrucosa cutis. Mantoux tests were done except one case and were reactive in all cases. Culture for Mycobacterium tuberculosis were done but Mycobacterium tuberculosis were not cultivated in the all cases. Histopathological findings showed tuberculoid granulomas in the dermis except one case and no acid fast bacilli were demonstrated on AFB stains.
Coloring Agents
;
Dermis
;
Granuloma
;
Incidence
;
Mycobacterium tuberculosis
;
Tuberculosis
;
Tuberculosis, Cutaneous*
;
Tuberculosis, Pulmonary
5.Antimycotic susceptibility testing of trichophyton rubrum by microculture method.
Moo Woong LEE ; Jong Chul KIM ; Jong Soo CHOI ; Ki Hong KIM
Yeungnam University Journal of Medicine 1992;9(2):396-406
Various susceptibility tests have been used to determine minimal inhibition concentration (MIC) of dermatophytes. They have limitations to apply practically because they need long time to determine MiC. Authors examined MIC of T. rubrum to ketoconazole and itraconazole using 96- well microplate and 24-well macroplate by method of Granade and Artis and tried to check the possibility of this method on clinical application. Nine strains of T. rubrum from patients with dermatophytosis were used. Evaluations of the factors affecting MIC were also tried. The results as follows. 1. Effect of inoculation density on determination time and MIC: Determination of MIC were possible in 4th days after inoculation at higher inoculation density (aborbance 2.0, 1.0) compared to 6th days at lower inoculation density (absorbance 0.5, 0.25). 2. Effect of incubation temperature on MIC: When incubating at 37℃, MIC were below 0.006-0.04µg/ml to ketoconazole and below 0.006-0.04µg/ml to itraconazole while at 25℃ 0.08-5.68µ8/ml to ketoconazole and 0.006-0.71µg/ml to itraconazole. Significant reduction of MIC was observed at 37℃ compared to 25℃. 3. Effect of container size on determination time and MIC: When incubating in 96–well microplate and 24-well macroplate, determination of MIC was possible in 4th to 6th days after inoculation in broth-containig 96-well microplate compared to 8th to 12th days in broth-containing 24-well macroplate. But no difference in MIC was observed between different container size. 4. Effect of media on MIC: When using broth as media, MIC were below 0.006-5.68µg/ml to ketoconazole, below 0.006-0.36µg/ml to itraconazole in broth-containg 24-well macroplate. When using agar as media, MIC were below 0.006-5.68 µg/ml to ketoconazole, below 0.006-5.68 µg/ ml to itraconazole in agar-containing 24-well macroplate. 5. These findings confirm that determination of MIC of dermatophtes by method of Granade and Artis is fast and simple technique for antifungal susceptibility test.
Agar
;
Arthrodermataceae
;
Humans
;
Itraconazole
;
Ketoconazole
;
Methods*
;
Tinea
;
Trichophyton*
6.Vaginoplasty with penile and scrotal skin flap in male to female transsexualism.
Seong Woong PARK ; Jaime JORCHE ; Domingo LEYES ; Sivlo MELVIN ; Nae Ho LEE ; Kyung Moo YANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(6):1039-1045
Transsexuals are those who have appropriate chromosomal, hormonal and anatomical characteristics corresponding to their sexual phenotype but feel strongly with respect to their sexual identity, that they belong to the opposite sex. For this reason, they wish to be reassigned to their psychological sex by means of endocrinological and surgical treatment. Although its etiology is unknown, the majority of modern psychiatrists and behavioral scientists agree that the transsexualism is a disease entity belonging to gender identity disorder or gender dysphoria but not to be confused with the transversite, honosexualism or psychiatric problem. Three kinds of hermaphroditism have been defined according to the histology of the gonad : female pseudohermaphroditism, male pseudohermaphroditism and true hermaphroditism. It is very difficult, if not possible to assign sex especially in neonate and young children. Once sex assignment has been decided and accepted by the patient, surgical intervention should be undertaken as soon as possible. For adults there are many kinds of operative techniques. We have operated 28 cases of transexualism patients by using the penile and scrotal skin flap. This technique is superb for improving sexual appearance and function, and finally for a good opportunity for social activity. We report the results of surgery.
46, XX Disorders of Sex Development
;
46, XY Disorders of Sex Development
;
Adult
;
Child
;
Disorders of Sex Development
;
Female*
;
Gender Identity
;
Gonads
;
Humans
;
Infant, Newborn
;
Male*
;
Ovotesticular Disorders of Sex Development
;
Phenotype
;
Psychiatry
;
Skin*
;
Transsexualism*
7.Photochemotherapy of Vitiligo with Topical Methoxsalen and longwave ultraviolet light.
Jai Ill YOON ; Woong Suck SUH ; Moo Hyung LEE ; Soo Duk LIM
Korean Journal of Dermatology 1982;20(2):221-230
Vitiligo is a common acquired Thypornelanotic disease but the pathogenesis is still unknown and also the traatment is still unsatisfactory. The introduction in 1947 of psoralen therapy in vitiligo by El Mofty announced a new era in the treatment of this cosmetically disfiguring disease. Many investigators have developed therapeutic regimens for both topical and systemic poralen using various ligbt sources. The erythema action spectrum in UVA range of psoralen were defined, which consequently enabled the development of a more accurate regimen, namely psoralen and UVA(FUVA, exposure. The present study was undertaken to evaluate the efficacy of topical PUVA therapy in patients with vitiligo and to compare the result of PUVA therapy according to the age, sex, type of disease, total exposure dose, duration of disease nd involved site. Twenty one patients selected in the Department of Dermatology of Kyung hee University Hospital with various clinical types of vitiligo were treated with 03% 8-MOP ointment followed by exposure to longwave ultraviolet energy. Clinical response was graded as follows: Grade 0: No repigmentation Grade 1; Up to 25% repigmentaton Grade 2; 25% to 50% repigmentation Grade 3; 50% to 90% repigmentation Grade 4; Greater than 90% repigmentation A responsive case wss defined as a case with greater than 25% repigmentation. A effective case was defined as a case with greater than 50;o repigmentation.
Dermatology
;
Erythema
;
Ficusin
;
Humans
;
Methoxsalen*
;
Photochemotherapy*
;
PUVA Therapy
;
Research Personnel
;
Ultraviolet Rays*
;
Vitiligo*
8.Familial Lupus Erythematosus Occurred in Mother and Son.
Tae Hun KWAK ; Moo Woong LEE ; Jong Soo CHOI ; Ki Hong KIM
Korean Journal of Dermatology 1995;33(5):950-955
The pathogenesis of lupus er thematosus(LE) appears to be multifactorial, including genetic, hormonal and environmental influences. Genetic factors have long been suspected to an important role in its pathogenesis. This was been shown in family studies and twin studies. We report a family in which mother developed SLE and son developed DLE. The mother, 35 year old female, had hyperpigmcnted brownish macules and atrophic scars on the face and also complained of fever, chill and arthralgia for 2 years. The clinical, laboratory and histopathological findings showed characteristic features of systemic lupus erythematosus. she had been treated with systemic prednisolone, hydrcxychloroquin sulfate and topical corticosteroid ointment for about 4 years resulting favorable improvement skin lesions. Laboratory studies during her course had demonstrated persist leukopenia, peckled pattern ANA and VDRL positive. The son, 10-year-old, had peasized, multiple erythematous papules and plaques on the face and arms for 2 months. The lirical, laboratory and histopathological findings showed characteristic features of discoid lupus erythematosus. He was treated with systernic prednisolone for 2 years, hydroxychloroquin sulfate and topical corticosteroid ointment for abcut 4 years resulting nearly all clearing of skin lesions with slighthly hyperpigmentation. Laboratory studies during his course had demonstrated only weakly ANA positive.
Adult
;
Arm
;
Arthralgia
;
Child
;
Cicatrix
;
Female
;
Fever
;
Humans
;
Hyperpigmentation
;
Leukopenia
;
Lupus Erythematosus, Discoid
;
Lupus Erythematosus, Systemic
;
Mothers*
;
Naphazoline
;
Prednisolone
;
Skin
9.An Observation in Coronary Collateral Circulation and Left Ventricular Function.
Se Woong SEO ; Moon Sung LEE ; Sang Moo LEE ; Hwo Joo HWANG ; Sung Gu KIM ; Young Joo KWON
Korean Circulation Journal 1988;18(3):337-343
After the performance of 100 coronary cineangiographies in 100 paitents who were adminitted to Soonchunhyang University Hospital under the diagnosis of ischemic heart disease from July 1986 to October 1987, we observed the coronary collateral circulation and measured the ejection fraction, circumferential fiber shortening, left ventricular end-diastolic pressure and pulmonary artery wedge pressure in 52 paitents who had 50% or more stenosis in one or more coroanry arteries. The results were as follow : 1) The collaterall circulation was observed in 16 patients(30.8%) of the 52 patients and it was developed mainly(87.5) in patients with 90% or more coronary artery stenosis. In patients with stenosis of less than 90%, however, collateral circulation was observed rarely(12.5%). 2) The left ventricular wall motion abnormality was severe in the group without collateral circulation. 3) The collteral circulation was most frequently developed in patients with severe right coronary artery stenosis and most of the routes were supplied from contralateral coronary arteries. 4) There was no significant difference in ejection fraction, circumferential fiber shortening, left ventricular end-diastoic pressure and pulmonary artery wedge pressure between the 2 groups with and without coronary artery collateral circulation.
Arteries
;
Cineangiography
;
Collateral Circulation*
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Stenosis
;
Coronary Vessels
;
Diagnosis
;
Humans
;
Myocardial Ischemia
;
Pulmonary Wedge Pressure
;
Ventricular Function, Left*
10.Plasma Atrial Natriuertic Peptide (ANP) Levels and Hemodynamic Data in Patient with Heart Disease.
Moon Sung LEE ; Sang Moo LEE ; Tae Myung CHOI ; Se Woong SEO ; Sung Gu KIM ; Young Joo KWON
Korean Circulation Journal 1988;18(1):23-29
To difine the relation between plasma atrial natriuertic peptide (ANP) levels and hemodynamic changes, we measured plasma concentration of atrial natriuertic peptide in 19 patients with heart disease undergoing cardiac catherization and in 15 normal subjects. The following results were obtained; 1) There were significantly increased plasma levels of atrial natriuertic peptide in patients with elevated mean pulmonary arterial wedge pressure. 2) A significant step-up in atrial natriuertic peptide concentration was seen between the femoral venous and right atrial plasma (P<0.01) and between the right atrial and pulmonary arterial plasma (P<0.05). 3) Peripheral venous atrial natriuretic peptide levels were significantly correlated with mean pulmonary arterial pressure and pulmonary wedge pressure (r=0.05, r=0.65, P<0.05). 4) Plasma atrial natriuretic peptide levels in pulmonary artery were significantly correlated with mean pulmonary arterial pressure (P<0.05).
Arterial Pressure
;
Heart Diseases*
;
Heart*
;
Hemodynamics*
;
Humans
;
Plasma*
;
Pulmonary Artery
;
Pulmonary Wedge Pressure