1.Urgent Application of Extracorporeal Membrane Oxygenation in Amniotic Fluid Embolism.
Korean Journal of Critical Care Medicine 2016;31(3):179-180
No abstract available.
Amniotic Fluid*
;
Embolism, Amniotic Fluid*
;
Extracorporeal Membrane Oxygenation*
;
Female
;
Pregnancy
3.A biomechanical study of two methods of internal fixation of fractures of femoral neck.
Kwang Suk LEE ; Moo Kyeong KO ; Jong Woong PARK
The Journal of the Korean Orthopaedic Association 1993;28(3):1140-1152
No abstract available.
Femur Neck*
4.The effects of estrogen and progesterone on vascular reactivity of endothelium-denuded human uterine artery.
Suk Woo HONG ; Byung Moo PARK ; Min HUR ; Moo Yeol LEE
Korean Journal of Obstetrics and Gynecology 2000;43(11):1947-1957
OBJECTIVES: The present study was performed to investigate whether estrogen and progesterone induce the change of vascular tone in endothelium-denuded human uterine artery and vascular reactivity may be mediated by intracelluar calcium modulation through receptor- and voltage-dependent calcium channels. METHODS: The uterine arteries were obtained at the time of hysterectomy from 28 women followed by denudation of endothelium. After confirmation of functional integrity of endothelium-denuded uterine artery, vascular reactivity was measured by using isometric force transducer and recorded by physiograph. Contraction was induced by 10-6 M norepinephrine and 35mM high concentrated potassium chloride solution which activated receptor-dependent calcium channel and voltage-dependent calcium channel, respectively.Thereafter estradiol of 4 different concentrations from 3x10-11M to 3x10-8M was administered. Progesterone was also administered to endothelium-denuded uterine artery which was contracted by 10-6M norepinephrine and high potassium chloride solution. To evaluate the effect of additional progesterone on vascular smooth muscle relaxation effect of estrogen,4 different progesterones in concentrations from 3x10-8M to 3x10-5M were given to vascular smooth muscle which was initially pretreated with norepinephrine followed by relaxation of estradiol. RESULTS: Estradiols from 3x10-11M to 3x10-8M showed in significant dose-dependent vascular relaxation. Progesterones result in significant decrease in vascular contraction in concentration dependent manner. Additional progesterone on estrogenic effects also results in significant decrease in vascular contraction. CONCLUSION: Estradiol may have endothelium independent vasorelaxation effect in human uterine artery. These vasorelaxant effects may be mediated through antagonistic action for receptor-and voltage-dependent calcium channels in vascular smooth muscle. Progesterone also bring about vasorelaxation by same action in endothelium-denuded vascular smooth muscle. On estrogen induced vascular relaxation, progesterone results in additional vasorelaxation.
Calcium
;
Calcium Channels
;
Endothelium
;
Estradiol
;
Estrogens*
;
Female
;
Humans*
;
Hysterectomy
;
Muscle, Smooth, Vascular
;
Norepinephrine
;
Potassium Chloride
;
Progesterone*
;
Relaxation
;
Transducers
;
Uterine Artery*
;
Vasodilation
5.A Case of Bilateral Adrenal Ganglioneuroma.
Suk San PARK ; Moo Sung MOON ; Jin Moo LEE
Korean Journal of Urology 1979;20(4):401-405
The great chain of sympathetic ganglia which extends from the base of the skull to the pelvis, including the suprarenal medulla, accounts for the origin of the ganglioneuroma which compound with the matured ganglion cells and neural elements. The ganglioneuroma is non-functioning tumor, but occasionally this tumor accompanies with hypertension and diarrhea and increased excretion of vanilmandelic acid in urine. Recently we experienced a housewife with the bilateral ganglioma which developed at both suprarenal medulla and after successful removal of the tumors hypertension was controlled.
Diarrhea
;
Ganglia, Sympathetic
;
Ganglion Cysts
;
Ganglioneuroma*
;
Hypertension
;
Pelvis
;
Skull
;
Vanilmandelic Acid
6.A Case Study of Congenital Hypothyroidism Caused by Ectopic Thyroid.
Eui Soo PARK ; Sang Hee CHO ; Gwi Jong CHOI ; Chong Moo PARK ; Suk Shin CHO
Journal of the Korean Pediatric Society 1983;26(8):803-807
No abstract available.
Congenital Hypothyroidism*
;
Thyroid Dysgenesis*
7.Relationship Between Initial Biochemical Bone Markers and Change of Bone Mineral Density of Postmenopausal Women with Short-term Hormone Replacement Therapy.
Sung Young PARK ; Yoo Suk SUH ; Sung Jun YOON ; Hyoung Moo PARK ; Min HUR
Korean Journal of Obstetrics and Gynecology 1999;42(9):1972-1979
OBJECTIVE: This study is proposed to examine the relationship between bone loss after hormone replacement therapy for one year and initial bone markers. METHODS: One hundred postmenopausal women were studied for one year. At first visit, measurements were made of bone mineral density(BMD) at the lumbar spine and femoral neck, and of serum osteocalcin and urine deoxypyridinoline. After hormone replacement therapy was done for one year, BMD was rechecked. RESULTS: Serum osteocalcin was correlated with the rate of bone change(r=0.150, 0.262) and urine deoxypyridinoline was weakly correlated(r=-0.003, 0.038). The changes of femoral BMD in women with higher concentration of osteocalcin and deoxypyridinoline were significant different from those in women with normal concentration. At the lumbar spine, no significant differences were showed. In women with higher concentration of osteocalcin, the incidence of subjects with increased spine BMD was increased up to around 71.1%, which showed not significant increase compared with normal concentration of osteocalcin. And the incidence of increased spine BMD in women with higher concentration of osteocalcin was marked increased compared with the incidence of normal concentration. The level of the osteocalcin with increased spine BMD was 11.5+/-6.6 ng/ml, and the level with decreased spine BMD was 9.2+/-4.7 ng/ml, respectively. And the level of the deoxypyridinoline was 7.2+/-4.2 pmol/ mol cr in women with increased spine BMD and 7.2+/-2.7 pmol/ mol cr in women with decreased spine BMD, which was not statistically different. The concentration of deoxypyridinoline with increased and decreased in BMD in spine and femur was not statistically different. but the concentration of osteocalcin was 12.2 +/-5.5 ng/ml in significantly increased in BMD and 8.5 +/-4.5ng/ml in significantly decreased in BMD, which was showed significant different. CONCLUSION: Present study indicates that the serum osteocalcin more reflcets bone turnover changes at the menopause than deoxypyridinoline, however, the clinical utility of measurements of osteocalcin only to response to therapy is uncertain.
Bone Density*
;
Female
;
Femur
;
Femur Neck
;
Hormone Replacement Therapy*
;
Humans
;
Incidence
;
Menopause
;
Osteocalcin
;
Spine
8.A Case of Bartter'S Syndrome.
Yung Suk SONG ; Moon Ho CHUNG ; Ha Baik LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1983;26(6):611-615
No abstract available.
Bartter Syndrome*
9.Clinical Study of the Paranasal Sinusitis in Childhood.
Young Suk SONG ; Kwang Nam KIM ; Gwi Jong CHOI ; Chong Moo PARK ; Hyung Seok LEE
Journal of the Korean Pediatric Society 1984;27(9):877-882
No abstract available.
Sinusitis*
10.Diagnosis and Treatment of Hypersensitivity Pneumonitis.
Journal of the Korean Medical Association 2009;52(1):49-58
Hypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is an immunologically mediated granulomatous, inflammatory disease of the lungs caused by repeated inhalation of various antigens. HP may occur in acute, subacute, or chronic forms. Chronic HP may be progressive, irreversible, and evolve to fibrotic interstitial lung disease. The diagnosis of HP can be made from a combination of clinical, laboratory, radiologic, and pathologic findings. A careful environmental and occupational history and establishment of exposure to a known inciting antigen are key factors in making the diagnosis of HP. Serum precipitating antibodies, bronchoalveolar lavage, and lung biopsy may be helpful in making the diagnosis. The pathology of HP is characterized by interstitial lymphocytic infiltration, poorlyformed noncaseating granulomas, cellular bronchiolitis, and fibrosis. In the pathogenesis of HP, recent studies showed that both type III and type IV hypersensitivity reactions are involved and are mediated by immune complexes and Th1 T cells, respectively. IFN-gamma is essential for the development of HP, and IL-10 appears to modulate the severity of the disease. TNF-alpha and TGF-beta have been implicated in development of the pulmonary fibrosis that is seen in chronic HP. Avoidance of organic antigen exposure is the most important factor for the management of HP. There is often an apparent beneficial response to corticosteroids in the cases of severe acute and subacute HP, and for chronic HP that is severe or progressive.
Adrenal Cortex Hormones
;
Alveolitis, Extrinsic Allergic
;
Antibodies
;
Antigen-Antibody Complex
;
Biopsy
;
Bronchiolitis
;
Bronchoalveolar Lavage
;
Fibrosis
;
Granuloma
;
Hypersensitivity
;
Hypersensitivity, Delayed
;
Inhalation
;
Interleukin-10
;
Lung
;
Lung Diseases, Interstitial
;
Pulmonary Fibrosis
;
T-Lymphocytes
;
Transforming Growth Factor beta
;
Tumor Necrosis Factor-alpha