No abstract available.
Leukemia* ; Leukemia, Megakaryoblastic, Acute*

'Marjolin' ulcer' is used to describe the malignant transformation of a chronic ulcer which has developed in a burn scar. Clinically, although the lesions is slowly progressive, it comes to be more aggressive when the scar barrier is disrupted. We reviewed 24 cases in patients who complained of chronic burn wounds suspected to be Marjolin's ulcer. The mean latent period for developing pathologic lesions was 31 years. Histologically, chronic ulcer and pseudoepitheliomatous hyperplasia were 21% respectively, while malignancy including squamous cell carcinoma and leiomyosarcoma was 56%. The mean elapsed time to diagnose squamous cell carcinogma was 33.2 years. In pseudoepitheliomatous hyperplasia which is considered as a transitional state to malignant tumor, wide excision and reconstruction with free muscle flap was a better procedure than skin graft for the prevention of recurrence and malignant transformation. As well, the same modality of treatment was also applied in malignant tumors.
Burns* ; Carcinoma, Squamous Cell ; Cicatrix ; Humans ; Hyperplasia ; Leiomyosarcoma ; Recurrence ; Skin ; Transplants ; Ulcer ; Wounds and Injuries*

Teratocarcinoma is a form of mixed germ cell tumor composed of a mixture of teratoma and embryonal carcinoma. It is rarely found in the brain, but when present it is most commonly found in the pineal region. We investigated a case of primary teratocarcinoma in the pineal region. The patient was a 10 year old boy who had suffered from a bitemporal headache for one month. Brain CT and MRI revealed a rather well defined ovoid heterogenous mass in the pineal gland region, measuring 4.3 x 3.8 x 3.0 cm in size. Microscopically the tumor contained areas of immature teratoma and embryonal carcinoma. Immunohistochemical staining revealed positive reactions for cytokeratin, epithelial membrane antigen, carcinoembryonic antigen, and alpha-fetoprotein in the embryonal carcinoma component.

A case or right occipital lobe infarction initially detected by the visual field examination and confirmed with the computerized tomography is presented. Reduction of significance of visual field test for identification of intracranial lesion as, the initial diagnostic procedure after the orientation of computerized tomography is unlikely. An occipital lobe lesion developed following posterior cerebral artery thrombosis has introd uced silgnificant ophthalmic symptom, namey, visual field defect, diplopia, ipsilateral ocular pain, visual hallucination, photophobia, and Anton's syndrom, etc. A characteristic feature of left homonymous hemianopsia with macular sparing due to right posterior cerebral artery thromb osis is demonstrated.
Diplopia ; Hallucinations ; Hemianopsia ; Infarction* ; Occipital Lobe* ; Photophobia ; Posterior Cerebral Artery ; Thrombosis ; Visual Field Tests ; Visual Fields

This report describes a primary malignant melanoma which developed in the anus, as documented by light microscopy and immunohistochemistry. A 53-year-old woman had a 4 month history of a protruding mass in the anal canal. The mass was located in the squamo-columnar junction of the anal canal, measuring 5.0x4.5 cm. Its cut surface was dark brown and poorly circumscribed. The histologic appearance was characterized by epithelioid or spindle cells with prominant nucleoli and frequent atypical mitosis. Melanin pigments were strongly seen in Fontana-Masson stain. Immunoreactivity revealed that the cytoplasm of tumor cells was strongly positive with antibody directed against S-100 protein, vimentin and it was focally positive with neuron specific enolase.
Female ; Humans

Although a patient with lost inferior rectus (IR) muscle woud be done infratransposition of the horizontal recti to control hypertropia, this procedure only could control ocular deviation at primary position, but could't improve the limitation of the downgaze markedly and could cause limitation of abduction and adduction. Authors tried to correct lost IR with anterior transposition of the inferior oblique muscle(IO) with marginal myectomy in the theoretical base that the anterior transposition of the IO can convert IO a depressor from an elevator. A 66 year-old female patient received trauma on her left IR muscle by sickle, then primary deviation of left eye was hypertropia of 50 prism diopters, exotropia of 35 prism diopters and secondary deviation was hypertropia 60 prism diopters, exotropia of 40 prism diopters and the degree of limitation of infraduction was -4. We performed anterior transposition of the IO with marginal myecctomy of 6.0 mm and lateral rectus (LR) 6.0 mm recession and medial rectus (MR) 4.5 mm resection of the left eye. The postoperative ocular alignment at primary position was exotropia of 10 prism diopters and degree of limitation of infraduction was -2 and limitation of supraduction was -2. The anterior transposition of IO with marginal myectomy was simple and effective in correcting the hypertropia and ocular motility in a case of lost IR.
Aged ; Elevators and Escalators ; Exotropia ; Female ; Humans ; Strabismus

BACKGROUND: Generalized immune activation occurs early in the course of many infectious disease. Laboratory investigations have shown that immune activation can be quantified by the measurement of soluble immune activation products in serum. Soluble CD25, CD8, and CD4 are major immune activation products. Soluble CD8 and CD4 are indices of CD8+ T cell and CD4+T cell activity, respectively. OBJECTIVE: We estimated the concentrations of these molecules in patients with leprosy. METHODS: The study population consisted of 31 patients with tuberculoid leprosy and 71 patients with lepromatous leprosy(32 cases of M. leprae negative patients and 39 cases of M. leprae positive patients). Serum samples and clinical and laboratory data were collected form each patient and control. The levels of serum soluble CD25, CD8, and CD4 were measured by sandwich enzyme immunoassay. RESULTS: The levels of serum soluble CD25 were significantly raised in leprosy patients as compared to control and did not vary signficantly between tuberculoid and lepromatous leprosy. The soluble CD8 levels in the serum of patients with leprosy did not differ from the levels of the control. The levels of serum soluble CD4 were significantly decreased in the patients with lepromatous leprosy, but not in the patients with tuberculoid leprosy. However, there was no significant correlation between CD25, CD8, and cD4 and bacterial indices in patients with lepromatous leprosy. CONCLUSIONs: There data suggest that non-specific immune activation occurs the spectrum in leprosy, while CD4+ T cell activity is significantly decreased in patients with lepromatous leprosy.
Communicable Diseases ; Humans ; Immunoenzyme Techniques ; Leprosy* ; Leprosy, Lepromatous ; Leprosy, Tuberculoid

No abstract available.
Agaricales* ; Anemia, Aplastic* ; Humans

The following conclusions deduced from the data of upper limbs injured persons 966 (total: 2,294) who visited first aid center located in ski resort in Kangwon province during every winter season from 2004 to 2008. The researcher themselves looked into the data accumulated and organized with respect to frequent types, and frequent parts of upper limbs injury. The most frequently injured body parts found from this investigation were upper limbs (42.1%), trunk region (30.7%), lower limbs (27.2%) in order. The injury of upper limbs (42.1%, n=966) was the most frequently cited snowboard injury. Among the patients of upper limbs injury, the male comprised of 23.9% (n=549) and female comprised 18.2% (n=417). The common parts of injuries were hands (50.3%, n=486) and shoulder (17.6%, n=170). the general types of injury of hands were fracture (15.4%, n=149), sprain and ligament injury (13.0%, n=126), dislocation (12.5%, n=121), contusion (7.9%, n=76), laceration (1.4%, n=14) in order.
Contusions ; Dislocations ; Female ; First Aid ; Hand ; Health Resorts ; Human Body ; Humans ; Lacerations ; Ligaments ; Lower Extremity ; Male ; Seasons ; Shoulder ; Skiing ; Sprains and Strains ; Upper Extremity

No abstract available.
Child* ; Heart Diseases* ; Heart* ; Humans ; Incidence* ; Tricuspid Valve Insufficiency*