No abstract available.

We reviewed 63 urolithiasis patients who were admitted to the Department of Urology, College of Medicine, Yonsei University during the period of 6 months from December, 1983 to May, 1984 to discover hyperparathyroidism in urolithiasis and to evaluate the relationship between PTH and urolithiasis. The following results were obtained. 1. Among 63 urolithiasis patients, there were 47 men and 16 women with a ratio of 2.9: 1 And peak age incidence of urolithiasis occurred in the third and fourth decades (68.3 %). 2. Urinary calculi occurred most commonly in the upper ureter (33.3%) and in decreasing order of frequency kidney and ureter (17.5 %), kidney (16.8 %). 3. In urolithiasis patients, elevated PTH level was found in 5 cases (7.9%) and hypercalciuria was found in 10 cases (15.9 %).And elevated PTH level with hypercalciuria was found in 2 cases(3.2%). 4. In urolithiasis patients, the range of serum calcium, phosphate, protein, albumin and urinaryphosphate, creatinine were within normal limit. And the range of TRP, TRCa were within normal limit, too. 5. Urolithiasis patients with elevated PTH had serum calcium level higher than urolithiasis patients with normal PTH and the difference of the values was statistically significant (P<0.01). But in serum calcium, phosphate, urinary phosphate, TRP and TRCa, the differences of the values between the elevated PTH group and normal PTH group were not statistically significant(p>0.01).
Calcium ; Creatinine ; Female ; Humans ; Hypercalciuria ; Hyperparathyroidism ; Incidence ; Kidney ; Male ; Parathyroid Hormone ; Ureter ; Urinary Calculi ; Urolithiasis* ; Urology

The relationship between Sertoli cells and germ cells in varicocele remains controversial. To study this relationship in varicocele, seminiferous tubular changes were observed in pubertal rats according to the length of time after induction of the varicocele and the interval between induction and repair of the varicocele. As the length of time of the varicocele increased, accumulation of lipid inclusions within the Sertoli cell cytoplasm appeared first and then premature sloughing of the early spermatids appeared. Lastly, decrease in testicular weight and mean seminiferous tubular diameter (MSTD) together with decrease in the number of late spermatids were observed. Inter-Sertoli cell junctions were preserved unrelated to the duration of the varicocele. When Sertoli cell changes were reversed after varicocele repair, premature sloughing of the early spermatids was not observed. The testicular weight, MSTD and number of late spermatids were significantly increased compared to controls. When Sertoli cell changes were not fully reversed after varicocele repair, premature sloughing of the early spermatids was still observed. The testicular weight, MSTD and number of late spermatids were not significantly increased compared to controls. These results suggest that the blood-testis barrier remains intact in varicocele. The Sertoli cell is the primary intratubular site of alteration leading secondarily to spermatogenic disruption in varicocele. Changes in the Sertoli cell cause premature sloughing of the early spermatids and affect maximally the spermatid Stage.
Animals ; Blood-Testis Barrier ; Cytoplasm ; Germ Cells* ; Intercellular Junctions ; Rats* ; Sertoli Cells ; Spermatids ; Varicocele*

The characterisitic finding of hypertrophic cardiomyopathy is left ventricular hypertrophy without dilated chamber. Echocardiographic studies of patients with pheochromocytoma in the past have revealed both dilated and hypertrophic cardiomyopathies, as well as obstruction of the left ventricular outflow tract. We report this case because we experienced a pheochromocytoma patient who had reversible hypertrophic cardiomyopathy which might be related with circulating catecholamine level.
Cardiomyopathy, Hypertrophic* ; Echocardiography ; Humans ; Hypertrophy, Left Ventricular ; Pheochromocytoma*

A 45-year-old female with psychosis complained urological symptom of urinary incontinence and voiding difficulty with abdominal pains and expansion during her psychiatric hospitalization and suddenly collapsed at the 14th day of the admission. At autopsy, the urinary bladder showed a focal perforation and the abdominal cavity was filled with massive urinary ascites. The both lower lobes and the right upper lobe of the lung were accompanied by atelectasis. The death mechanism of this case could be explained that an increased abdominal pressure produced by massive uroperitoneum with spontaneous bladder rupture led to respiratory failure. The so-called abdominal compartment syndrome was manifested by massive uroperitoneum and caused a death. This would be the first forensic medical case that an undiagnosed spontaneous bladder rupture resulted in death of a psychiatric illness patient.
Abdominal Cavity ; Abdominal Pain ; Ascites ; Autopsy ; Female ; Hospitalization ; Humans ; Intra-Abdominal Hypertension ; Lung ; Middle Aged ; Psychotic Disorders ; Pulmonary Atelectasis ; Respiratory Insufficiency ; Rupture* ; Urinary Bladder* ; Urinary Incontinence

The concentration of transferrin in seminal plasma from 16 cases of normal controls and 61 cases of infertile men has been evaluated in order to identify the relationship between seminal transferrin concentrations, human semen parameters and plasma FSH levels. The seminal transferrin concentrations were found to be significantly lower in patient with azoospermia and oligo-asthenospermia as compared with findings for normal controls(p<0.05). A significant positive correlation was found between sperm count and seminal transferrin levels (r=0.2480, p<0.05). However. no significant correlations were obtained to sperm motility and sperm morphology (p>0.05). No significant differences in seminal transferrin concentration were observed in the groups with obstructed azoospermia. Non-obstructed azoospermia and men who had had a vasectomy (p>0.05). And a significant correlation was not found between seminal transferrin and circulating FSH in patients with azoospermia (p>0.05). In conclusion. it is suggested that seminal tansferrin originates mainly from the testis and is significantly correlated to sperm density. These results, however, results, however, do not clarify whether the cause of azoospermia is obstructed or non-obstructed. So, for the study of patients with azoospermic infertility, the epididymal marker is necessary to differentiate obstructive and non-obstructive cases.
Azoospermia ; Humans ; Infertility ; Male ; Plasma ; Semen ; Sperm Count ; Sperm Motility ; Spermatozoa ; Testis ; Transferrin* ; Vasectomy

Trsnssexualism, one of the gender identity disorders, has been increasing and evokes a serious social problem. The role of sex reassignment surgery in these patients are still controversial but in properly selected patients sex reassignment surgery is the best way to normalize their lives. However. guidelines for the proper selection of the patients for surgery is not yet established in Korea So. we present our experiences of two male transsexuals treated with rectosigmoid vaginoplasty and introduce the prerequisites to sex reassienment surgery.
Gender Identity ; Humans ; Korea ; Male* ; Sex Reassignment Surgery* ; Social Problems ; Transsexualism*

We report a case of Castleman`s disease of the hyaline-vascular type which was located in retroperitoneum. A 20-year-old girl was admitted because of a history of postprandial epigastric discomfort. Computed tomography of the abdomen demonstrated a solid 7 x 7 cm mass between the abdominal aorta and the left kidney in the retroperitoneum. At surgery, a solid 9 x 8 x 6 cm tumor was resected. Pathologic diagnosis was Castleman`s disease of the hyaline-vascular type.
Abdomen ; Aorta, Abdominal ; Diagnosis ; Female ; Humans ; Kidney ; Young Adult

Adrenal cortical tumor is a rare disease both in adults and children. Most of these tumors are malignant and functional, especially in children, producing endocrine syndrome such as virilization, Cushing's syndrome, hyperaldosteronism or feminization. Recently, we experienced a case of adrenal cortical tumor in a 26 month-old boy who showed features of virilization. This case was diagnosed with typical hormonal findings and abdominal CT and confirmed by pathologic examinations. He was successfully treated with right adrenalectomy. We report a case of virilizing adrenal cortical tumor and review the literature.
Adrenalectomy ; Adult ; Child* ; Child, Preschool ; Cushing Syndrome ; Feminization ; Humans ; Hyperaldosteronism ; Male ; Rare Diseases ; Tomography, X-Ray Computed ; Virilism

A small-cell carcinoma of the gallbladder is an uncommon cancer with high malignancy potential. It is usually found in elderly women and is associated with cholelithiasis. These tumors show an aggres sive clinical course and death usually occurs within a few months after diagnosis. The diagnosis of a small-cell carcinoma should be based on cell morphology, histologic pattern, and immunohistochemical study. Correct diagnosis is important not only because these tumors give rise to endocrine syndrome but also because the chemotherapeutic approach to a small-cell carcinoma differs from that for an adeno carcinoma. We experienced a case of a small-cell carcinoma of the gallbladder in a 73-year-old woman with acute cholecystitis syndrome. She was treatment with a palliative cholecystectomy and chemotherapy with short-term excellent response. The literature on the subject is reviewed.
Aged ; Carcinoma, Small Cell* ; Cholecystectomy ; Cholecystitis, Acute ; Cholelithiasis ; Diagnosis ; Drug Therapy ; Female ; Gallbladder* ; Humans