2.Monoclonal Gammopathy of Undetermined Significance Presented as a Vasculitic Neuropathy.
Sang Soo LEE ; Dong Ick SHIN ; Sung Hyun LEE ; Yun Hui KIM
Journal of the Korean Neurological Association 2006;24(5):524-526
No abstract available.
Monoclonal Gammopathy of Undetermined Significance*
;
Paraproteinemias*
;
Vasculitis
3.Concurrence of Fibrillary Glomerulonephritis and AL Amyloidosis Associated with Monoclonal Gammopathy.
Dong Suk CHANG ; Won Ik JANG ; Dae Eun CHOI ; Ki Ryang NA ; Kwang Sun SUH ; Yong Tai SHIN ; Kang Wook LEE
Korean Journal of Nephrology 2011;30(2):187-190
Renal diseases with organized deposits include amyloid, fibrillary, immunotactoid, and cryoglobulinemic glomerulopathies. AL amyloidosis and fibrillary glomerulonephritis are different in the composition of their immunoglobulin deposits. Fibrils of fibrillary glomerulonephritis are usually composed of polyclonal, occasionally oligoclonal or monoclonal, immunoglobin G, but amyloidosis consists of monoclonal light chains. Simultaneous occurrence of fibrillary glomerulonephritis and AL amyloidosis is very rare. We report a case of fibrillary glomerulonephritis combined with AL amyloidosis in a 71-yr-old man.
Amyloid
;
Amyloidosis
;
Glomerulonephritis
;
Immunoglobulins
;
Light
;
Monoclonal Gammopathy of Undetermined Significance
;
Paraproteinemias
4.Clinical Application of (18)F-FDG PET in Multiple Myeloma.
Nuclear Medicine and Molecular Imaging 2009;43(6):509-512
This review focuses on the clinical use of (18)F-FDG PET to evaluate multiple myeloma. (18)F-FDG PET is useful for diagnosis, staging of multiple myeloma and differential diagnosis of myeloma related disease such as monoclonal gammopathy of undetermined significance or plasmacytoma. For therapy response, (18)F-FDG PET may be effective after chemotherapy for multiple myeloma and radiotherapy for plasmacytoma.
Diagnosis, Differential
;
Monoclonal Gammopathy of Undetermined Significance
;
Multiple Myeloma
;
Plasmacytoma
7.Concomitant transformation of monoclonal gammopathy of undetermined significance to multiple myeloma and of essential thrombocythemia to acute biphenotypic leukemia 37 years after initial diagnosis.
Pasquale NISCOLA ; Gianfranco CATALANO ; Stefano FRATONI ; Laura SCARAMUCCI ; Paolo DE FABRITIIS ; Tommaso CARAVITA
Blood Research 2013;48(3):228-230
No abstract available.
Leukemia, Biphenotypic, Acute
;
Monoclonal Gammopathy of Undetermined Significance
;
Multiple Myeloma
;
Paraproteinemias
;
Thrombocythemia, Essential
8.Coexistence of AA and AL Cardiac Amyloidosis in a Patient with Ankylosing Spondylitis Accompanying Monoclonal Gammopathy of Undetermined Significance.
Woohyeon KIM ; Seon A KIM ; Kyung Jin YUN ; Soo Jin NA ; Ji In HYUN ; Jung Im JUNG ; Seung Ki KWOK ; Sung Hwan PARK
Journal of Rheumatic Diseases 2014;21(3):151-155
Amyloidosis is a clinical disorder caused by extracellular deposition of proteinaceous insoluble fibrils in various tissues, resulting in organ compromise. Amyloid L (AL) amyloidosis is the most common type of systemic amyloidosis, which occurs in association with multiple myeloma or monoclonal gammopathy of undetermined significance (MGUS). Secondary amyloid A (AA) amyloidosis is a complication of chronic inflammatory conditions, such as rheumatoid arthritis or ankylosing spondylitis. We report a case of a 49-year-old manwith a 11-year history of ankylosing spondylitis, who was recently diagnosed with MGUS presented with cardiac amyloidosis of both the AA and AL types. We report this case along with a review of relevant literature.
Amyloid
;
Amyloidosis*
;
Arthritis, Rheumatoid
;
Humans
;
Middle Aged
;
Monoclonal Gammopathy of Undetermined Significance*
;
Multiple Myeloma
;
Spondylitis, Ankylosing*
9.Polyneuropathy Associated with IgA Paraproteinemia and Amyloidosis: A Case Report and Literature Review.
Yunsook JHANG ; Jung Ju LEE ; Jong Moo PARK ; Ja Seong KOO ; Byung Kun KIM ; Ohyun KWON
Journal of Clinical Neurology 2007;3(2):116-119
Paraproteinemia potentially causes peripheral neuropathy via an unknown underlying pathogenetic mechanism. We report a case of pathologically proven amyloid neuropathy with AL amyloidosis with an IgA kappa light chain, which was initially diagnosed as neuropathy associated with monoclonal gammopathy of undetermined significance. This case indicates that in cases of neuropathy with paraproteinemia, the other potential causes should be excluded by appropriate means, especially pathological evaluations.
Amyloid Neuropathies
;
Amyloidosis*
;
Immunoglobulin A*
;
Monoclonal Gammopathy of Undetermined Significance
;
Paraproteinemias*
;
Peripheral Nervous System Diseases
;
Polyneuropathies*
10.The Association between Multiple Myeloma and Ankylosing Spondylitis: A Report of Two Cases.
Hyung Il MOON ; Hyoung Jin CHANG ; Ji Eun KIM ; Hoon Young KO ; Soe Hee ANN ; Chang Ki MIN
Korean Journal of Hematology 2009;44(3):182-187
Multiple myeloma is a malignant disease of plasma cells, whereas ankylosing spondylitis is a chronic inflammatory disease of axial joints. The relationship between the two diseases is uncertain, but chronic inflammation could trigger multiple myeloma. The authors report the cases of two ankylosing spondylitis patients with a disease duration of more than 20 years, that subsequently developed IgA kappa and IgG lambda chain myeloma, respectively, and discuss the possible pathogenetic relationship between these diseases.
Humans
;
Immunoglobulin A
;
Immunoglobulin G
;
Inflammation
;
Joints
;
Monoclonal Gammopathy of Undetermined Significance
;
Multiple Myeloma
;
Plasma Cells
;
Spondylitis, Ankylosing