1.Chemical Components of Phellinus and Antitumor Mechanism: A Review
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(8):275-282
Malignant tumor poses a threat to human health and life. The incidence and fatality rate of malignant tumor have been on the rise. The currently available therapies are radiotherapy and chemotherapy, which cause severe adverse reactions and irreversible damage and thus influence the quality of life of patients. Therefore, it is urgent to find new, safe and effective antitumor drugs. Chinese medicinals are safe with little adverse reactions and long-lasting effect in the treatment of tumor, which have attracted the attention of scholars. Amid the advancement of medical research, more and more anti-tumor components have been extracted from Chinese medicinals. Phellinus is a valuable Chinese medicinal material, and the chemical components mainly include polysaccharides, flavonoids, triterpenes, and polyphenols, which have anti-inflammatory, hypoglycemic, liver-protecting, and anti-tumor effect. The chemical components of Phellinus can inhibit various malignant tumors such as lung cancer, gastric cancer, colon cancer, and melanoma. It exerts the anti-tumor effect by inhibiting proliferation and metastasis of tumor cells, inducing apoptosis and autophagy of the cells, suppressing tumor angiogenesis, and regulating the immunity. In addition, it can enhance efficacy, reduce toxicity, and boost the sensitivity in the radiotherapy and chemotherapy. In this paper, articles were retrieved from China National Knowledge Infrastructure (CNKI), Web of Science, Pubmed, and Google Scholar with keywords such as "Phellinus, chemical components, and anti-tumor", and then the chemical components of Phellinus and the anti-tumor mechanisms were summarized. The findings are expected to lays a basis for further development and clinical application of this medicinal.
2.Exploration on Acupuncture and Moxibustion Treatment Ideas for Gynecological Reproductive Diseases Based on the"Heart-kidney-Chong Ren-uterus"Reproductive Axis
Mohao ZHU ; Ling QIU ; Wenhua HAN ; Tianya YAN ; Yixuan XING ; Shi TANG ; Weiai LIU ; Zhaoling YOU
Chinese Journal of Information on Traditional Chinese Medicine 2024;31(2):167-172
This article mainly elaborated the acupuncture and moxibustion treatment scheme of"eighteen needles for reproduction"based on Professor You Zhaoling's reproductive axis theory of"heart-kidney-Chong Ren-uterus".The"eighteen needles for reproduction"aims to regulate the disordered reproductive axis in gynecological reproductive diseases.It selects the acupoints on the main viscera and meridians of the reproductive axis as the main acupoints,and the acupoints regulating the qi and blood of the related viscera as the matching acupoints.Through specific manipulation,it can regulate the qi and blood,dredge the meridians,and treat the viscera,so as to nourish the essence and help pregnancy,and provide ideas and reference for the treatment of gynecological reproductive diseases with acupuncture and moxibustion.