1.Scolicidal Effects of Olea europaea and Satureja khuzestanica Extracts on Protoscolices of Hydatid Cysts.
Mohammad ZIBAEI ; Amanallah SARLAK ; Bahram DELFAN ; Behrouz EZATPOUR ; Alireza AZARGOON
The Korean Journal of Parasitology 2012;50(1):53-56
Treatment of hydatid disease is mainly surgical, with medical treatment being reserved as a coadjuvant treatment. Use of effective scolicidal agents during surgery of cystic echinococcosis is essential to reduce the recurrence rate. The goal of this study was to evaluate the in vitro scolicidal effects of hydroalcoholic extracts of Satureja khuzestanica leaves and aqueous extracts of Olea europaea leaves on hydatid cyst protoscolices. Echinococcus granulosus protoscolices were collected from the liver of sheep infected with the hydatid cyst. Various concentrations of plant extracts were used in different exposure times for viability assay of protoscolices. Among the olive leaf extracts tested, 0.1% and 0.01% concentrations had strong scolicidal effects in 120 min. S. khuzestanica 0.1% had very strong scolicidal effects in 30, 60, and 120 min of exposure times and the mortality rate decreased with the lower concentration. The finding have shown that the scolicidal activity of S. khuzestanica against cystic echinococosis protoscolices were more effective, while the O. europaea extract showed less effects.
Animals
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Anthelmintics/*pharmacology
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Dose-Response Relationship, Drug
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Echinococcosis/drug therapy/*parasitology
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Echinococcus granulosus/drug effects/physiology
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Humans
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Olea/*chemistry
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Plant Extracts/*pharmacology
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Plant Leaves/chemistry
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Satureja/*chemistry
2. Traditional effects of medicinal plants in the treatment of respiratory diseases and disorders: An ethnobotanical study in the Urmia
Mohsen ASADBEIGI ; Mahmoud BAHMANI ; Tahereh MOHAMMADI ; Mohammad DELFAN ; Mahmoud RAFIEIAN-KOPAEI ; Kourosh SAKI
Asian Pacific Journal of Tropical Medicine 2014;7(S1):S364-S368
Objective: To identify, present and review the respiratoty medicinal plants which used by Urmian herbalists. Methods: The list of traditional healers of West Azarbaijan Province was prepared and data were obtained by direct observation, interviews and the questionnaires After that, herbarium samples were collected from the desired area and deposited in herbarium unit of the Faculty of Agriculture, Urmia University, Urmia, Iran. Results: Our results demonstrated that 20 medicinal plants from 10 plant families are used to treat respiratory disorders. Also, the most plant part that used for treating of respiratory disorders was seed (27%) and the most traditional form prescribed by herbalists was boiled (54%). Forty three percentage of Urmia herbalists have used herbs for the treatment of cough. Conclusions: People in this area have a strong belief that plants have a positive impact in the treatment of respiratory disorders and they have used medicinal plants since ancient times to treat these disorders. Our study revealed the importance of herbal medicines and traditional medicine in this area as medicinal resource for drug discovery in future.