1.Ketamine-Associated Ulcerative Cystitis: A Case Report and Literature Review
Christopher Chee Kong Ho ; Hafez Pezhman ; Singam Praveen ; Eng Hong Goh ; Boon Cheok Lee ; Md Zainuddin Zulkifli ; Mohamed Rose Isa
Malaysian Journal of Medical Sciences 2010;17(2):61-65
Ketamine can be abused as a recreational drug, and there has been a recent surge in its
usage. The effects of ketamine on the urinary system were unknown until the recent publication
of a few case reports. Many doctors are still unaware of this new clinical entity, termed ketamineassociated
ulcerative cystitis. We report a case that we encountered and discuss the diagnosis and
disease management in addition to a review of the literature.
2.Distribution of gastric adenocarcinoma subtypes in different ethnicities in Kuala Lumpur, Malaysia
Asif SUKRI ; Alfizah HANAFIAH ; Nik Ritza KOSAI ; Mustafa Mohamed TAHER ; Isa Mohamed ROSE
The Malaysian Journal of Pathology 2017;39(3):235-242
The multiracial population in Malaysia has lived together for almost a century, however, the risk ofgastric cancer among them varies. This study aimed to determine the distribution of different gastricadenocarcinoma subtypes and Helicobacter pylori infection status among gastric adenocarcinomapatients. Patients with gastric adenocarcinoma were enrolled from November 2013 to June 2015.Blood samples were collected for detection of H. pylori using ELISA method. Gastric adenocarcinomacases were more prevalent in the Chinese (52.8%), followed by the Malays (41.7%) and leastprevalent in the Indians (5.6%). Gastric adenocarcinoma located in the cardia was significantly moreprevalent in the Malays (66.7%) compared to the Chinese (26.3%), whereas non-cardia cancer wasdiagnosed more in the Chinese (73.7%) compared to the Malays (33.3%) [P = 0.019; OR = 5.6, 95CI: 1.27 to 24.64]. The Malays also had significantly higher prevalence of gastric tumour locatedat the cardia or fundus than other gastric sites compared to the Chinese (P = 0.002; OR: 11.2, 95%CI: 2.2 to 56.9). Among the cardia gastric cancer patients, 55.6% of the Malays showed intestinalhistological subtype, whereas all the Chinese had the diffuse subtype. More than half of the patients(55.3%) with gastric adenocarcinoma were positive for H. pylori infection and among them, 66.7%were Chinese patients. The risk of gastric adenocarcinoma in our population is different amongethnicities. Further studies on host factors are needed as it might play an important role in gastriccancer susceptibility in our population.
3.Synovial sarcoma: a rare presentation of parapharyngeal mass.
Mohd Mokhtar SHAARIYAH ; Ami MAZITA ; Mansor MASAANY ; Mohd Yunus RAZIF ; Mohamed Rose ISA ; Abdullah ASMA
Chinese Journal of Cancer 2010;29(6):631-633
Synovial sarcoma is a rare soft tissue sarcoma of the head and neck region involving the parapharyngeal space. The diagnosis of synovial sarcoma can be very challenging to the pathologists. We present a rare case of parapharyngeal synovial sarcoma in a young female patient who had a two-month history of left cervical intumescent mass at level II. The fine needle aspiration cytology of the mass was proved inconclusive. Transcervical excision of the mass was performed and the first case of parapharyngeal sarcoma was identified in our center by fluorescence in situ hybridization (FISH) technique. Repeat imaging revealed residual tumor. The patient successfully underwent a second excision of the residual tumor and received adjuvant radiotherapy.
Adult
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Biopsy, Fine-Needle
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Combined Modality Therapy
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Female
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Humans
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In Situ Hybridization, Fluorescence
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Neoplasm, Residual
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Pharyngeal Neoplasms
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diagnosis
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pathology
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radiotherapy
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surgery
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Radiotherapy, Adjuvant
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Sarcoma, Synovial
;
diagnosis
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pathology
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radiotherapy
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surgery
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Tomography, X-Ray Computed