1.Novel Usage of Dexmetomidine In A Paediatric Patient With Giant Tongue Haemangioma
Mohd Zulfakar Mazlan ; Shamsul Kamalrujan Hassan ; Laila Abd Mukmin ; Mohd Hasyizan Hassan ; Huda Zainal Abiddin ; Irfan Mohamad ; Chandran Nadarajan ; Rubinderan Muthusamy ; Chong Soo Eu
Malaysian Journal of Medicine and Health Sciences 2016;12(2):53-55
Giant haemangioma of the tongue is a disease which can
obstruct the oropharyngeal airway and is presented with
obstructive symptoms. Due to its vascularity, inserting
laryngoscope for intubation can cause high risks, such as
inducing bleeding. Hypoxia and excessive bleeding must be
anticipated while securing the airway. We present a case of
novel usage of dexmetomidine as a conscious sedation agent for
awake fibre optic intubation in a 9-year-old child with
obstructive symptoms secondary to a huge tongue
haemangioma, who was presented for interventional
sclerotherapy of the lesion.
Tongue
2.Balanced Fluid Versus Saline-Based Fluid in Post-operative Severe Traumatic Brain Injury Patients: Acid Base and Electrolytes Assessment
Mohamad Hasyizan Hassan ; Wan Mohd Nazaruddin Wan Hassan ; Rhendra Hardy Mohd Zaini ; Wan Fadzlina Wan Muhd Shukeri ; Huda Zainal Abidin ; Chong Soon Eu
Malaysian Journal of Medical Sciences 2017;24(5):83-93
Background: Normal saline (NS) is a common fluid of choice in neurosurgery and neurointensive
care unit (ICU), but it does not contain other electrolytes and has the potential to cause
hyperchloremic metabolic acidosis with prolonged infusion. These problems may be reduced
with the availability of balanced fluid (BF), which becomes a more physiological isotonic solution
with the presence of complete electrolyte content. This study aimed to compare the changes in
electrolytes and acid–base between NS and BF (Sterofundin® ISO) therapy for post-operative
severe traumatic brain injury (TBI) patients in neuro-ICU.
Methods: Sixty-six severe TBI patients who required emergency craniotomy or
craniectomy and were planned for post-operative ventilation were randomised into NS (n = 33)
and BF therapy groups (n = 33). The calculation of maintenance fluid given was based on the
Holliday-Segar method. The electrolytes and acid–base parameters were assessed at an 8 h
interval for 24 h. The data were analysed using repeated measures ANOVA.
Results: The NS group showed a significant lower base excess (-3.20 versus -1.35,
P = 0.049), lower bicarbonate level (22.03 versus 23.48 mmol/L, P = 0.031), and more
hyperchloremia (115.12 versus 111.74 mmol/L, P < 0.001) and hypokalemia (3.36 versus 3.70
mmol/L, P < 0.001) than the BF group at 24 h of therapy. The BF group showed a significantly
higher level of calcium (1.97 versus 1.79 mmol/L, P = 0.003) and magnesium (0.94 versus 0.80
mmol/L, P < 0.001) than the NS group at 24 h of fluid therapy. No significant differences were
found in pH, pCO2, lactate, and sodium level.
Conclusion: BF therapy showed better effects in maintaining higher electrolyte
parameters and reducing the trend toward hyperchloremic metabolic acidosis than the NS
therapy during prolonged fluid therapy for postoperative TBI patients.
3.A Comparison Between Measured Maxillopharyngeal Angle On Lateral Cervical Radiograph with Modified Mallampati Classification In Predicting Difficult Larnygoscopy: A Blinded Interventional Study
Mohamad Hasyizan HASSAN ; Eng Ming FUNG ; Rhendra Hardy Mohd Zaini ; Shamsul Kamalrujan HASSAN ; Praveena SEEVAUNNAMTUM ; Mohd Zulfakar MAZLAN ; Nik Abdullah Nik Mohamad
Malaysian Journal of Medicine and Health Sciences 2018;14(2):51-56
Background: Existing techniques of predicting difficult laryngoscopy are inadequate requiring evaluation of Maxillopharyngeal Angle (MP-A) on lateral cervical radiograph described. Objectives: This study aimed to compare MP-A test with Modified Mallapati Test (MMT) in predicting their diagnostic values and Area Under Curve of Receiver Operating Characteristic Curve (AUCROCC) of both test. Methods: This is a double blinded interventional study of 93 patients. Each patient’s MMT score was assessed during preoperative assessment and subsequent MP-A test done by obtaining lateral cervical radiograph with the head in neutral position. Laryngeal view was assessed using Cormack-Lehane grade after induction of anesthesia, was used as reference standard to determine the diagnostic values of MMT and MP-A respectively. Results: The MP-Acompared to MMT in predicting difficult larngoscopy had higher sensitivity (77.78 vs 44.44) specificity (88.10 vs 67.86) and accuracy (87.10 vs 65.59) with higher Odd Ratio(26.12 vs 1.68). The AUCROCC was significantly higher in MP-A test 0.83(95%CI: 0.67, 0.99) (P = 0.001) vs MMT 0.56(95%CI: 0.36, 0.76) (P = 0.546) with LR+ of 6.53 vs 1.38. Conclusion: The Maxillopharyngeal Angle test was superior in predicting difficult laryngoscopy as compared to Modified Mallampati Test.difficult intubation