This case involved an 86-year-old woman. She had suffered from vomiting, abdominal pain, distension and constipation, 3 times in 3 years.
Her constipation episodes were not complicated by ileus. There were no obstructive lesions on two colonoscopies.
She again suffered from same symptoms in March 2012. Abdominal radiography and CT scans showed significant gasses in her intestine along with a large volume of stool. The previous treatments had not been effective. So we switched to hachimigan with her. This Kampo medicine was very effective. Eight days after hachimigan administration start, all symptoms were relieved. Moreover, no constipation was observed in a 1 year course of hachimigan treatment. We thus conclude that hachimigan was very effective for this patient's constipation.

There are cases of intractable eye pain, which can be difficult to treat. The late Shogo Yamamoto treated un­explained eye pain with various Chinese herbal prescriptions. Among them, there were clinical trials of heating agents including orengedokuto and hangeshashinto, but no trials of orento are mentioned. Further, no trials of cases of eye pain treated with orento were found in several other collections of clinical trials ;however, here we report on two cases of intractable eye pain of unknown origin that showed significant effects when admin­istered orento. In case 1, unexplained eye pain appeared after cataract surgery and after various treatments were found to be ineffective, acupuncture treatment in our hospital showed a positive effect. In case 2, unex­plained eye pain developed without any obvious cause, and the pain was increased by acupuncture treatment at our hospital. A common finding in both cases was objective cooling of the upper abdomen. The eye pain was considered to be upper heat and the abdominal pain to be middle cold, thus a diagnosis of upper heat and mid­dle cold was made and orento administration begun. We therefore consider that orento could be listed as a treatment for unexplained eye pain.