Objective:To evaluate the meaning of arthrography with cone-beam CT（CBCT） imaging in the diagnosis of temporomandibular disorders(TMD).Methods:Four hundred and forty-eight cases of temporomandibular upper joint cavity arthrography with CBCT imaging were retrospectively analyzed. The distribution of disc displacement with reduction or without reduction, disc perforation, enlargement or tearing of joint capsule were analyzed. The characteristics of arthrography with CBCT imaging were also described.Results:There were 384 female and 64 male among the 448 cases of TMD with CBCT arthrographic images. The median age was 31.5 years， range from 14 to 81 years old. As about the age distribution, there were 63 cases in the group of ≤20 years old, 150 cases in the group of >20 and ≤30 years old, 86 cases in the group of >30 and ≤40 years old, 59 cases in the group of >40 and ≤50 years old, 58 cases in the group of>50 and ≤60 years old, and 32 cases in the group of >60 years old. There were 356 cases with disc displacement, in which there were 328 cases of disc displacement without reduction, and 28 cases of disc displacement with reduction. There were 152 cases with disc perforation, and 12 cases with articular capsule tearing or laxation.Conclusions:Arthrography with CBCT imaging was a meaningful approach to diagnose the TMD with structure disorders.