1.Factors Influencing Family's Organ Donation Decision.
Jaesook OH ; Minsun KANG ; Kyung Sook JANG ; Hyun Jin KANG ; Wonhyun CHO ; Jongwon HA
The Journal of the Korean Society for Transplantation 2017;31(3):133-142
BACKGROUND: The main factor limiting the increase in brain dead organ donors is low consent rates for organ donation. METHODS: This study is a retrospective analysis of donor records of Korea Organ Donation Agency from 2013 to 2015. Factors related before providing information about organ donation and process of explaining organ donation were analyzed. RESULTS: Donor gender, marital status, religious affiliation, residence area, knowledge of patients' wishes, understanding of brain death status, and the referring system, providing initial information about donation and initial medical staff providing information about donation had a significant influence on decision to donate. Organ donation greatly increased when the donor family knew the patient's intent to donate. As the degree of family understanding of brain death status and the referring system increased, organ donation rate significantly increased. CONCLUSIONS: Providing sufficient information about brain death during the period of delivering medical services as well as activating campaign and public education are essential to improving the positive attitude toward organ donation.
Brain Death
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Education
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Humans
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Korea
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Marital Status
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Medical Staff
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Retrospective Studies
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Tissue and Organ Procurement*
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Tissue Donors
2.Cytologic Featrues of Pituitary Adenoma: A Case Report by Fine Needle Aspiration.
Minsun CHO ; Mi Jung KIM ; Sung Sook KIM ; Hea Soo KIM ; Sung Min JEOUNG ; Sung Hak KIM
Korean Journal of Cytopathology 1994;5(2):184-188
Therapeutic management of brain tumors is based on accurate knowledge of their size, location and histologic type. Stereotaxic cytology under CT guidance has been applied to the investigation of brain tumors, especially in the sellar turcica, third ventricle, and pineal regions. In the present case, the tumor protruded into the nasal cavity, so we were able to get cytologic material via fine needle aspiration.
Biopsy, Fine-Needle*
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Brain Neoplasms
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Nasal Cavity
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Pituitary Neoplasms*
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Third Ventricle
3.The Effect of Group Education Reflecting Unmet Needs on Knowledge of Chemotherapy for Patients and Their Families Undergoing Chemotherapy: A One Group Pre-Post Design
Seyoung LEE ; Hoyoung KIM ; Nayeon KIM ; Misun YI ; Ayoung LEE ; Seonmi CHO ; Minsun NAM ; Juhee CHO
Asian Oncology Nursing 2024;24(1):42-51
Purpose:
The purpose of this study is to determine the effect of group education reflecting unmet needs led by Nurse Practitioners (NPs) on essential knowledge regarding chemotherapy for cancer patients and their families undergoing chemotherapy.
Methods:
Conducted at a tertiary general hospital in Seoul from December 30, 2020, to April 30, 2022, this study, which is based on a one group pre-post design, involved 104 cancer patients and their families. It assessed differences in knowledge regarding chemotherapy and satisfaction levels by means of participation through video-based group education led by NPs. The data were analyzed with SAS version 9.4 using paired t-tests and multiple logistic regression analysis.
Results:
The average score of knowledge regarding chemotherapy increased from 80.0 to 89.8 (p<.001). In multivariable logistic regression analysis, being less than 50 years old (adjusted Odds Ratio [aOR]=13.56, 95% Confidence Interval [CI]: 1.76~10.20) and having a college degree or higher (aOR=3.99, 95% CI: 1.15~13.82) were associated with an increase in knowledge regarding chemotherapy. Satisfaction with participation in the group education program was also reported to be high.
Conclusion
This study aimed to develop and implement a group education program for cancer patients and their families undergoing chemotherapy, assess changes in knowledge levels, and investigate satisfaction with the program. As a result of the study, the average score of patients who received the group education program increased; thus, it is an effective method for improving the degree of knowledge about the daily life of cancer patients and the management of side effects.
4.Subsequent pregnancy and long-term safety after breast cancer: a retrospective analysis of Korean health insurance data
Minsun KANG ; Yong Soon CHUN ; Heung Kyu PARK ; Eun Kyung CHO ; Jaehun JUNG ; Yunyeong KIM
Annals of Surgical Treatment and Research 2022;102(2):73-82
Purpose:
Long-term safety of pregnancy after breast cancer (BC) remains controversial, especially with respect to BC biological subtypes.
Methods:
We analyzed a population-based retrospective cohort with BC from 2002 to 2017. Patient-level 1:1 matching was performed between pregnant and nonpregnant women. The study population was categorized into 6 biological subtypes based on the combination of prescribed therapies. Subanalyses were performed considering the time to pregnancy after BC diagnosis, systemic therapy, and pregnancy outcomes.
Results:
We identified 544 matched women with BC, who were assigned to the pregnant (cases, n = 272) or nonpregnant group (controls, n = 272) of similar characteristics, adjusted for guaranteed bias. These patients were followed up for 10 years, or disease and mortality occurrence after the diagnosis of BC. Survival estimates were calculated. The actuarial 10-year overall survival (OS) rates were 97.4% and 91.9% for pregnant and nonpregnant patients, respectively. The pregnant group showed significantly better OS (adjusted hazard ratio [aHR], 0.29; 95% confidence interval [CI], 0.12–0.68; P = 0.005) and did not have a significantly inferior disease-free survival (aHR, 1.10; 95% CI, 0.61–1.99; P = 0.760).
Conclusion
Consistent outcomes were observed in every subgroup analysis. Our observational data provides reassuring evidence on the long-term safety of pregnancy in young patients with BC regardless of the BC biological subtype.
5.Development of Web-Based Nomograms to Predict Treatment Response and Prognosis of Epithelial Ovarian Cancer
Se Ik KIM ; Minsun SONG ; Suhyun HWANGBO ; Sungyoung LEE ; Untack CHO ; Ju Hyun KIM ; Maria LEE ; Hee Seung KIM ; Hyun Hoon CHUNG ; Dae Shik SUH ; Taesung PARK ; Yong Sang SONG
Cancer Research and Treatment 2019;51(3):1144-1155
PURPOSE: Discovery of models predicting the exact prognosis of epithelial ovarian cancer (EOC) is necessary as the first step of implementation of individualized treatment. This study aimed to develop nomograms predicting treatment response and prognosis in EOC. MATERIALS AND METHODS: We comprehensively reviewed medical records of 866 patients diagnosed with and treated for EOC at two tertiary institutional hospitals between 2007 and 2016. Patients’ clinico-pathologic characteristics, details of primary treatment, intra-operative surgical findings, and survival outcomes were collected. To construct predictive nomograms for platinum sensitivity, 3-year progression-free survival (PFS), and 5-year overall survival (OS), we performed stepwise variable selection by measuring the area under the receiver operating characteristic curve (AUC) with leave-one-out cross-validation. For model validation, 10-fold cross-validation was applied. RESULTS: The median length of observation was 42.4 months (interquartile range, 25.7 to 69.9 months), during which 441 patients (50.9%) experienced disease recurrence. The median value of PFS was 32.6 months and 3-year PFS rate was 47.8% while 5-year OS rate was 68.4%. The AUCs of the newly developed nomograms predicting platinum sensitivity, 3-year PFS, and 5-year OS were 0.758, 0.841, and 0.805, respectively. We also developed predictive nomograms confined to the patients who underwent primary debulking surgery. The AUCs for platinum sensitivity, 3-year PFS, and 5-year OS were 0.713, 0.839, and 0.803, respectively. CONCLUSION: We successfully developed nomograms predicting treatment response and prognosis of patients with EOC. These nomograms are expected to be useful in clinical practice and designing clinical trials.
Area Under Curve
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Disease-Free Survival
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Humans
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Medical Records
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Nomograms
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Ovarian Neoplasms
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Platinum
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Prognosis
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Recurrence
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ROC Curve