OBJECTIVE: Henoch–Schönlein purpura is the most widespread systemic vasculitis during childhood. This study evaluated the relationship between neutrophil-lymphocyte ratio (NLR) and Henoch–Schönlein nephritis, which is important for the long-term prognosis of Henoch–Schönlein purpura. METHODS: We retrospectively reviewed patients diagnosed with Henoch–Schönlein purpura at the Department of Pediatrics of Soonchunhyang University Bucheon Hospital between January 2007 and June 2018. One hundred and twelve patients under the age of 18 who were diagnosed with Henoch–Schönlein purpura according to Henoch–Schönlein purpura diagnostic criteria, European League Against Rheumatism were included in the study. Blood and urine test, gastroscopy and colonoscopy, and abdominal computed tomography performed during the first visit were included. RESULTS: Among 112 Henoch–Schönlein purpura patients, 25 patients were Henoch–Schönlein nephritis. NLR was significantly increased in patients with Henoch–Schönlein nephritis compared to patients without nephritis (P=0.042), which is an independent predictor of Henoch–Schönlein nephritis. CONCLUSION This study showed that NLR could be a useful predictor of Henoch–Schönlein nephritis in patients with Henoch–Schönlein purpura.

Laryngomalacia, the most common cause of stridor in infants, is characterized by the inward collapse of soft and immature upper laryngeal cartilages during inspiration, resulting in airway obstruction at the supraglottic level. Acquired laryngomalacia is a rare condition that mainly occurs following significant neurological dysfunctions associated with cerebrovascular disease, head and neck surgery, or cervical trauma. We present a case of acquired idiopathic laryngomalacia in a 12-year-old adolescent caused by the prolapse of redundant arytenoid mucosa. The patient exhibited no neurological dysfunctions or laryngeal deformities. However, he had allergic rhinitis accompanied by high serum immunoglobulin E levels. His symptoms worsened after being infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Furthermore, allergic rhinitis or SARS-CoV-2 infection may have worsened preexisting asymptomatic congenital or acquired laryngomalacia through neurological damage. Acquired idiopathic laryngomalacia is rale in children. In cases where children and adolescents present with a sudden onset of inspiratory stridor, it is essential to perform a laryngoscopic examination for identifying potential cases of acquired laryngomalacia.