1.The application of AI in medical consumable classifier.
Haiyuan XIE ; Minli QIAN ; Jinsong LI
Chinese Journal of Medical Instrumentation 2014;38(5):386-388
Establish normal classifier of non-charge medical consumable and database of medical consumable inuse, is the basis of uniform classification and management of non-charge medical materials used in different hospital. It's an objective and effective method to classify by AI and set up the database, and has better classification accuracy.
Artificial Intelligence
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Databases, Factual
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Equipment and Supplies
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classification
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Materials Management, Hospital
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methods
2. Intervention study of compassion fatigue of oncology nurses in Balint group activities
Linyan YAO ; Minli XIANG ; Zhihong YE ; Ying QIAN ; Qin LU ; Linjuan YAN ; Liya JIANG ; Hongbo ZHONG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2017;35(12):910-913
Objective:
To explore the effectiveness of Balint group on compassion fatigue among oncology nurses.
Methods:
From January to December 2016, 35 oncology nurses from one general hospital were enrolled. 18 cases were allocated in the observation group and 17 cases in the control group by computer randomization. Nurses in the observation group were received a total of 8 times Balint Group activities, with 2 times a month and 1.5 hours each time, which is aiming to discuss difficult cases encountered in the clinic to help nurses have a deeper experience and a better understanding of the emotions and behaviors, fantasies and needs between nurse-patient interaction. Nurses in the control group without intervention. All the Participants were requested to complete the survey of the Professional Quality of Life (ProQOL) , the Jefferson Scale of Empathy-Health Professionals (JSE-HP) , and the General Health Questionnaire (GHQ) at pre and post intervention.
Results:
Before intervention, two group of nurses in age, working years, marriage, and education were not statistically significant (
3.Effect of comprehensive rehabilitation exercise after breast cancer surgery on functional rehabilitation of upper limb and quality of life
Minli RAO ; Chaoqun ZHENG ; Yindan QIAN
Chinese Journal of Primary Medicine and Pharmacy 2019;26(2):170-174
Objective To investigate the effect of comprehensive rehabilitation exercise on the rehabilitation of upper limb function and quality of life in patients with breast cancer. Methods From January 2014 to December 2017,68 cases received breast cancer surgery in Hangzhou Red Cross Hospital were chosen in the research. The patients were randomly divided into observation group (34 cases) and control group (34 cases). All the patients were given routine rehabilitation training,and the observation group was given latissimus dorsi muscle strengthening exercise and simplified 24 Style Taijiquan exercise. The upper limb function rehabilitation and quality of life of the two groups were compared and analyzed. Results At 2 months after operation, the angle of extension, the angle of internal rotation and the adduction strength in the observation group were (39. 43 ± 5. 82)°,(150. 7 ± 10. 34)° and (145. 24 ± 10. 35) N,respectively,which in the control group were (33. 71 ± 5. 28)°,(134. 10 ± 39. 43)° and (119. 57 ± 9. 46)N,respectively,which were significantly improved compared with those before discharge (t=12. 041,3. 883, 11. 807,4. 906,21. 904,11. 617,all P<0. 05),which in the observation group were significantly higher than those in the control group (t=4. 244,6. 166,10. 674,all P<0. 05). The pain,ADL and ROM scores in the observation group at 2 months after operation were ( 13. 27 ± 4. 51 ) points, ( 16. 48 ± 4. 22 ) points and ( 31. 46 ± 5. 64 ) points,respectively,which in the control group were ( 10. 73 ± 4. 15 ) points, ( 12. 05 ± 4. 13 ) points and ( 26. 57 ± 5. 16)points,respectively,which were significantly higher than before discharge (t=5. 238,2. 503,10. 953,5. 531, 12. 872,9. 160,all P<0. 05),which in the observation group were significantly higher than those in the control group (t=2. 417,4. 375,3. 730,all P<0. 05). The WHOQOL-BREF scores in the observation group at 2 months after operation were (17. 24 ± 2. 81) points,(16. 74 ± 3. 18) points,(17. 45 ± 2. 56) points,(33. 48 ± 5. 15) points, (3. 97 ± 1. 05)points and (3. 87 ± 1. 18)points,respectively,which in the control group were (14. 21 ± 3. 08)pionts, (13.81 ±3.28)points,(13.45 ±2.83)points,(28.81 ±4.82)points,(3.26 ±1.16)points,(3.18 ±1.28)points, respectively,compared with those before discharge,the differences were statistically significant(t =9. 669,4. 965, 8. 327,4. 857,10. 522,4. 198,11. 487,7. 132,5. 572,2. 688,5. 178,2. 727,all P<0. 05),which in the observation group were significantly higher than those in the control group(t=4. 238,3. 740,6. 112,4. 638,2. 646,2. 311,all P<0. 05). Conclusion A positive comprehensive rehabilitation exercise for the patients with breast cancer is helpful to the recovery of the function of the upper limb and the improvement of the quality of life of the patients.
4.Advances in Research on Pathological and Molecular Mechanism of Hyperuricemic Nephropathy Based on Animal Models
Fangqi BAO ; Haiye TU ; Mingsun FANG ; Qian ZHANG ; Minli CHEN
Laboratory Animal and Comparative Medicine 2024;44(2):180-191
Uric acid (UA), the final product of human purine metabolism, can cause hyperuricemia (HUA) when excessively accumulated. HUA is closely linked to chronic kidney diseases (CKD) and is considered an independent risk factor. Hyperuricemic nephropathy, a form of CKD induced by HUA, has seen significant advances in understanding through research into the pathogenic roles of uric acid and the development of HUA animal models. Although progress has been made in understanding the pathophysiological mechanisms by which UA induces CKD, much remains to be learned about its pathological molecular mechanisms. New approaches in animal modeling or the selection of model animals may potentially lead to significant breakthroughs in research on hyperuricemia as well as related CKD. This paper reviews the research progress on the molecular mechanisms of hyperuricemic nephropathy, focusing on oxidative stress, inflammation, autophagy, fibrosis, and gut microbiota. Oxidative stress is induced by uric acid intracellularly through xanthine oxidase, NADPH oxidases, and mitochondria, leading to cellular damage. In terms of inflammation, uric acid crystals can activate the NLRP3 inflammasome, triggering an inflammatory cascade. The role of free uric acid as a pro-inflammatory agent, however, remains controversial. Depending on the study conducted, autophagy has been found to either alleviate or exacerbate inflammation induced by uric acid. Fibrosis, particularly through epithelial-mesenchymal transition (EMT), is a major mechanism by which uric acid causes glomerulosclerosis and tubulointerstitial fibrosis. Extensive research has explored various signaling pathways involved in uric acid-induced EMT. Beneficial gut microbiota protect the kidneys by synthesizing short-chain fatty acids, reducing urea’s enterohepatic circulation, and decreasing uric acid production. This paper aims to enhance understanding of the complex relationships between HUA and CKD, serving as a reference for further research and new drug development.