1.Nodular Hyperplasia Arising from the Lateral Aberrant Thyroid Tissue: A Case Report.
Minhye JEONG ; Jeong Seon PARK ; Young Jun LEE
Journal of the Korean Society of Medical Ultrasound 2012;31(3):163-166
The presence of aberrant thyroid tissue in the lateral neck is very rare. In addition, nodular hyperplasia in ectopic thyroid has rarely been reported. Due to the unusual location, the presence of lateral aberrant thyroid tissue could be misdiagnosed as a lymphadenopathy, neurogenic tumor, etc. We report on a case of nodular hyperplasia arising from the right lateral aberrant thyroid tissue.
Congenital Abnormalities
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Hyperplasia
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Lymphatic Diseases
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Neck
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Thyroid Dysgenesis
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Thyroid Gland
2.Effects of Physical Activity on Fractures in Adults: A Community-Based Korean Cohort Study.
Minhye JANG ; Changwon WON ; Hyunrim CHOI ; Sunyoung KIM ; Woochul PARK ; Donghoo KIM ; Sujin JEONG ; Byungsung KIM
The Korean Journal of Sports Medicine 2017;35(2):97-102
Regular exercise and a certain level of physical activity reduce the mortality rate in the elderly. The purpose of this study was to investigate the effect of physical activity on the prevention of fracture in the middle aged or older in Korea. The basic data are based on the Ansan and Ansung community cohort studies of the Korean Genome and Epidemiology Study conducted by the Korea Centers for Disease Control and Prevention in 2001, and the fracture data from the third survey in 2005 to the sixth survey in 2011. The physical activity of the aged in the 40s was mostly distributed in the World Health Organization (WHO) recommended range of 7.5 to 30.0 metabolic equivalent·hr/wk, and the activity was gradually divided into the low and high groups in the 50s and 60s. In the 60s, the risk of fracture was reduced to 0.63 times compared to that of the 50s when physical activity was the recommended level (odds ratio, 0.63; p<0.001). For Korean adults, there was no significant difference in fracture incidence according to the amount of physical activity in the middle-aged people. However, for the elderly aged 60 and over, the risk of fracture decreased when the WHO recommended level of activity was performed, and the risk increased when less or more activities were performed.
Adult*
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Aged
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Centers for Disease Control and Prevention (U.S.)
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Cohort Studies*
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Epidemiology
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Fractures, Bone
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Genome
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Gyeonggi-do
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Humans
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Incidence
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Korea
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Middle Aged
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Mortality
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Motor Activity*
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World Health Organization
3.Higher mitochondrial DNA copy number is associated with lower prevalence of microalbuminuria.
Jung Eun LEE ; Hansoo PARK ; Young Seok JU ; Minhye KWAK ; Jong Il KIM ; Ha Young OH ; Jeong Sun SEO
Experimental & Molecular Medicine 2009;41(4):253-258
It has been suggested that mitochondrial dysfunction contributes to the initiation and development of atherosclerosis and cardiovascular disease. We examined the association between mitochondrial DNA (mtDNA) copy number and microalbuminuria in a cross-sectional community-based study. We measured peripheral blood mtDNA copy number in 694 adults without chronic kidney disease by a real-time PCR method. The overall prevalence of microalbuminuria (defined as an albumin creatinine ratio of 30 to 299 mg/g) was 4.5%. The prevalence of microalbuminuria decreased progressively from the lower to the upper quartiles of mtDNA copy number (6.9%, 5.7%, 2.9%, and 2.3% in quartiles 1, 2, 3, and 4, respectively, P = 0.017 for trend). Multiple logistic regression models showed that the quartile of mtDNA copy number was independently associated with the prevalence of microalbuminuria (P = 0.01 for trend). Compared with the lowest quartile, the highest quartile had an odds ratio of 0.22 for microalbuminuria (95% confidence interval, 0.05 to 0.87; P = 0.03). Higher mtDNA copy number was associated with the lower prevalence of microalbuminuria in a community-based population.
Adult
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Albuminuria/blood/*epidemiology/*genetics
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Cross-Sectional Studies
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DNA, Mitochondrial/blood/*genetics
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Female
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*Gene Dosage
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Humans
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Male
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Middle Aged
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Regression Analysis
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Young Adult