1.Prevalence of people with disabilities in Chi Linh
Thuy Thi Minh Nguyen ; Duy Sy Dang ; Huynh Van Hoang ; Quyen Ngoc Quach ; Michael Palmer
Journal of Medical Research 2008;58(5):99-105
Background: Surveys in disability are getting more and more attention from the Governments and contributes towards improve service provision for people with disabilities. Objective: To describe the prevalence of people with disabilities at The Chi Linh demographic and epidemiological surveillance system (CHILILAB), Hai Duong province in 2007. Subject and Method: The cross - cutting survey conducted in the CHILILAB which has a population of 65.438 people, the WHO questionnaire of disability screening was used. Result and conclusion: Disability prevalence in Chi Linh occurs in 28.2% of the population. It is noted that the disability prevalence increases significantly with age groups: 81.8% of those who are over 60, 58.2% those aged of 40 - 59 and only 8 - 9% of those aged under 40. In addition, the disability prevalence is higher in the rural areas, women, the poor and the illiterate. It is necessary to have more study on the prevalence of people with disabilities in wider ranges. \r\n', u'\r\n', u'\r\n', u'
Prevalence
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Disability prevalence
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Disability
2.Some characteristics of disabled people in Chi Linh district, Hai Duong province
Thuy Thi Minh Nguyen ; Quyen Ngoc Quach ; Huynh Van Hoang ; Duy Sy Dang ; Michael -- Palmer
Journal of Medical Research 2008;59(6):80-87
Background: People with disabilities have been coping with barriers that make it difficult for them to access public services. Many of them are poor, illiterate and out of work. Objective: To describe some characteristics of disabled people living in the communities of Chi Linh district, Hai Duong province. Subject and methods: Interview all of the 18.473 disabled people living in the seven communities of Chi Linh district, Hai Duong province. The contents of the interviews includes: economic-social information (income, education, job and martial status) and disability status (disability form and cause). Results: Nearly three fourths of disabled people are at the age of 45 and over. There are more women than men, with the male/female ratio at 1:1.8. Almost all of the disabled people are the Kinh in Chi Linh and 10.8% of them belong to the poor households. One in ten disabled people are illiterate and two thirds of disabled adolescents are at lower secondary school or lower. Difficulty in seeing is the most common among the kinds of disabilities, accounting for 81.9% of disabled people and about three fourths with one disability. Among the causes of disability, aging accounts for 71.5%, this is followed by illness. Conclusion: There is the need to reduce the rate of disability at the age of 45 and over, reducing the rate of sight related difficulties and increasing the accessibility of disabled people to educational services.
disability persons
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characteristics
3.Application of microplate almar blue assay for rapid detection of drug resistance of M. tuberculosis strains
Ly Minh Ho ; Hoa Thanh Tran ; Lien Kim Pham ; Hung Van Nguyen ; Phuong Thi Hoang ; Sy Ngoc Dinh
Journal of Preventive Medicine 2008;0(3):60-66
Background: Recently, microplate almar blue assay has been used commonly in detecting gen related to tuberculosis drug resistance, which provides results after 5-7 days with lower cost compared to traditional methods. Objective: To evaluate the application of microplate almar blue assay for rapid detection of drug resistance of M. tuberculosis strains. Subject and Method: A microplate-based assay which uses Alamar blue reagent - an oxidation reduction dye (MABA), was used for the determination of the anti-tuberculosis drug (isoniazid-INH, rifampicine-RIF, streptomycine-STR and ethabuton=EMB) resistance of 96 M. tuberculosis strains isolated from Vietnamese patients in comparison to those obtained by conversional method. Result: MABA showed to have high sensitivity and specificity in testing the sensitivity to individual anti-tuberculosis drugs (from 82.4% for STR to 93.3% for - INH and from 82.5% for EMB to 98.4% for STR; respectively), as well as for the multi-drug resistant M.tuberculosis (86.4% of sensitivity), highly correlated with the result determined by proportion method. Conclusion: MABA reveals the advantage in shortening test time, in simple performance and lower cost compared with the conversional culture based methods.
Microplate almar blue assay
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M. tuberculosis
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drug resistance
4.Facial artery: anatomical variations in the perioral region in cadavers
Vu Hoang NGUYEN ; Lin CHENG-KUAN ; Tuan Anh NGUYEN ; Trang Huu Ngoc Thao CAI
Archives of Craniofacial Surgery 2023;24(6):266-272
Background:
In recent years, there has been an increase in reports of perioral vascular complications resulting from filler injections, such as necrosis of the lip or alar rim, occlusion, and in severe cases, blindness. Conversely, the use of perioral arterial flaps is becoming more prevalent in the treatment of cleft lips, cancer, and trauma. A thorough understanding of perioral arteries is essential to minimize complications and maximize the success of these flaps. However, the course of the facial artery (FA) in the perioral region remains incompletely understood. The aim of this study was to describe the variations of the FA in the perioral region.
Methods:
We dissected 52 embalmed and formaldehyde-fixed Vietnamese cadavers. We then studied the size and distribution of perioral arteries in 102 specimens.
Results:
The superior labial artery (SLA) was the most common branch, occurring in 87.25% of cadavers, followed by the inferior labial artery (ILA) at 78.43%. The SLA primarily originated above the mouth corner (cheilion), accounting for 91.01% of cases, and predominantly exhibited a tortuous course within the submucosa (78.65%). The ILA’s branching pattern varied, but it was primarily located below the cheilion (91.25%). The ILA also followed a twisted path, generally within the submucosa. The ILA exhibited two patterns: the typical pattern, distributed at the vermilion border of the lower lip (8.82%), and the horizontal labiomental artery pattern, which ran horizontally in the middle of the lower lip area (69.61%). At their origin, the SLA and ILA had average external diameters of 1.29 mm and 1.28 mm, respectively.
Conclusion
Numerous anatomical variations in the FA in the perioral region were found. A detailed anatomic description, suggested landmarks, and angiography before the procedure will be useful to help doctors avoid complications.
5.The branching patterns and termination points of the facial artery: a cadaveric anatomical study
Vu Hoang NGUYEN ; Lin CHENG-KUAN ; Tuan Anh NGUYEN ; Trang Huu Ngoc Thao CAI
Archives of Craniofacial Surgery 2024;25(2):77-84
Background:
The facial artery is an important blood vessel responsible for supplying the anterior face. Understanding the branching patterns of the facial artery plays a crucial role in various medical specialties such as plastic surgery, dermatology, and oncology. This knowledge contributes to improving the success rate of facial reconstruction and aesthetic procedures. However, debate continues regarding the classification of facial artery branching patterns in the existing literature.
Methods:
We conducted a comprehensive anatomical study, in which we dissected 102 facial arteries from 52 embalmed and formaldehyde-fixed Vietnamese cadavers at the Anatomy Department, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Results:
Our investigation revealed eight distinct termination points and identified 35 combinations of branching patterns, including seven arterial branching patterns. These termination points included the inferior labial artery, superior labial artery, inferior alar artery, lateral nasal artery, angular artery typical, angular artery running along the lower border of the orbicularis oculi muscle, forehead branch, duplex, and short course (hypoplastic). Notably, the branching patterns of the facial artery displayed marked asymmetry between the left and right sides within the same cadaver.
Conclusion
The considerable variation observed in the branching pattern and termination points of the facial artery makes it challenging to establish a definitive classification system for this vessel. Therefore, it is imperative to develop an anatomical map summarizing the major measurements and geometric features of the facial artery. Surgeons and medical professionals involved in facial surgery and procedures must consider the detailed anatomy and relative positioning of the facial artery to minimize the risk of unexpected complications.
6.The impact of hyperandrogenism on the outcomes of ovulation induction using gonadotropin and intrauterine insemination in women with polycystic ovary syndrome
Vu Ngoc Anh HO ; Toan Duong PHAM ; Nam Thanh NGUYEN ; Hieu Le Trung HOANG ; Tuong Manh HO ; Lan Ngoc VUONG
Clinical and Experimental Reproductive Medicine 2022;49(2):127-134
Objective:
This study aimed to investigate the impact of hyperandrogenism (HA) on the outcomes of ovulation induction (OI) using gonadotropin and intrauterine insemination (IUI) in patients with polycystic ovary syndrome (PCOS).
Methods:
This was a retrospective cohort study including 415 patients undergoing OI using gonadotropin and IUI treatment between January 2018 and December 2020 at a single infertility center. Baseline characteristics, clinical and laboratory parameters, and pregnancy outcomes were investigated.
Results:
Among the study population, there were 105 hyperandrogenic (25.3%) and 310 non-hyperandrogenic patients (74.7%). The live birth rate was lower in the HA group than in the non-HA group, but this difference did not reach statistical significance due to the limited sample size (14.3% vs. 21.0%, relative risk=0.68; 95% CI, 0.41–1.14, p=0.153). No predictive factors for live birth were identified through logistic regression analysis.
Conclusion
HA did not negatively affect the outcomes of OI using gonadotropin and IUI cycles in Vietnamese women with PCOS. The result may not be applicable elsewhere due to the large variation in the characteristics of women with PCOS across races and populations.
7.Predictors of twin pregnancy in in vitro fertilization with intracytoplasmic sperm injection cycles with day 3 double embryo transfer
Duy Le NGUYEN ; Hieu Le-Trung HOANG ; Vu Ngoc-Anh HO ; Toan Duong PHAM ; Nam Thanh NGUYEN ; Van Thi-Thu TRAN ; Tuong Manh HO ; Lan Ngoc VUONG
Clinical and Experimental Reproductive Medicine 2024;51(1):69-74
Objective:
The purpose of this study was to identify factors associated with twin pregnancy following day 3 double embryo transfer (DET).
Methods:
This retrospective cohort study incorporated data from 16,972 day 3 DET cycles. The participants were women aged between 18 and 45 years who underwent in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) at My Duc Assisted Reproduction Technique Unit (IVFMD), My Duc Hospital, located in Ho Chi Minh City, Vietnam.
Results:
Of the 16,972 day 3 DET cycles investigated, 8,812 (51.9%) resulted in pregnancy. Of these, 6,108 cycles led to clinical pregnancy, with 1,543 (25.3% of clinical pregnancies) being twin pregnancies. Factors associated with twin pregnancy included age under 35 years (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.32 to 1.71; p<0.001) and cycles involving the transfer of at least one grade I embryo. Relative to the transfer of two grade III embryos, the risk of twin pregnancy was significantly elevated following the transfer of two grade I embryos (OR, 1.40; 95% CI, 1.16 to 1.69; p<0.001) or a combination of one grade I and one grade II embryo (OR, 1.27; 95% CI, 1.05 to 1.55; p=0.001).
Conclusion
By analyzing a large number of IVF/ICSI cycles, we identified several predictors of twin pregnancy. These findings can assist medical professionals in tailoring treatment strategies for couples with infertility.
8.Molecular and Clinicopathological Features of Gastrointestinal Stromal Tumors in Vietnamese Patients
Quoc Dat NGO ; Quoc Thang PHAM ; Dang Anh Thu PHAN ; Anh Vu HOANG ; Thi Ngoc Ha HUA ; Sao Trung NGUYEN
Journal of Pathology and Translational Medicine 2019;53(6):361-368
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal neoplasms of the gastrointestinal tract. Management of GIST patients is currently based on clinicopathological features and associated genetic changes. However, the detailed characteristics and molecular genetic features of GISTs have not yet been described in the Vietnamese population.METHODS: We first identified 155 patients with primary GIST who underwent surgery with primary curative intent between 2011 and 2014 at University Medical Center at Ho Chi Minh City, Vietnam. We evaluated the clinicopathological features and immunohistochemical reactivity to p53 and Ki-67 in these patients. Additionally, KIT genotyping was performed in 100 cases.RESULTS: The largest proportion of GISTs was classified as high-risk (43.2%). Of the 155 GISTs, 52 (33.5%) were positive for Ki-67, and 58 (37.4%) were positive for p53. The expression of Ki-67 and p53 were correlated with mitotic rate, tumor size, risk assessment, and tumor stage. Out of 100 GIST cases, KIT mutation was found in 68%, of which 62 (91.2%) were found in exon 11, two (2.9%) in exon 9, and four (5.8%) in exon 17. No mutation in exon 13 was identified. Additionally, KIT mutations did not correlate with any clinicopathological features.CONCLUSIONS: The expression of Ki-67 and p53 were associated with high-risk tumors. Mutations in exon 11 were the most commonly found, followed by exon 17 and exon 9. Additionally, KIT mutation status was not correlated with any recognized clinicopathological features.
Academic Medical Centers
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Asian Continental Ancestry Group
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Exons
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Gastrointestinal Stromal Tumors
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Gastrointestinal Tract
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Humans
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Molecular Biology
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Risk Assessment
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Vietnam
9.Objectively Measured Physical Activity of Vietnamese Adults With Type 2 Diabetes: Opportunities to Intervene
Vuong Van DO ; Jonine JANCEY ; Ngoc Minh PHAM ; Chung Thanh NGUYEN ; Minh Van HOANG ; Andy H. LEE
Korean Journal of Preventive Medicine 2019;52(2):101-108
OBJECTIVES: To objectively determine and compare the physical activity (PA) levels of adults newly diagnosed with type 2 diabetes (T2D) and adults without T2D in Vietnam using an accelerometer. METHODS: A total of 120 participants with newly diagnosed T2D and 120 adults without T2D were recruited from a large hospital in Hanoi, the capital city of Vietnam. All participants wore an ActiGraph GT3X accelerometer for at least 5 days, including 1 weekend day. Freedson cut-off points were used to estimate different intensities of PA. In addition, comparisons between groups were made with respect to achieving the World Health Organization (WHO) and International Diabetes Federation (IDF) recommended PA guidelines. RESULTS: Men with T2D had significantly lower levels of PA than men without T2D. The respective multivariable-adjusted mean values of daily step count, daily light-intensity, moderate-intensity, and moderate-to-vigorous-intensity PA were approximately 14%, 19%, and 22% lower in the men with T2D than in their non-T2D counterparts. However, women with T2D accumulated a greater number of steps per day than women without T2D. Only 59.2% of the adults with T2D met the minimum recommended level of PA (WHO and IDF), compared to 74.2% of adults without T2D (p<0.05). After adjusting for potential confounders, participants with T2D experienced 50.0% significantly lower odds of achieving PA recommendations. CONCLUSIONS: Vietnamese men with T2D were less physically active than those without T2D, and adults with T2D were less likely to meet PA guidelines. The results suggest a need for integrating PA into the self-management of this chronic condition.
Adult
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Asian Continental Ancestry Group
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Female
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Humans
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Male
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Motor Activity
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Self Care
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Vietnam
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World Health Organization
10.Objectively Measured Physical Activity of Vietnamese Adults With Type 2 Diabetes: Opportunities to Intervene
Vuong Van DO ; Jonine JANCEY ; Ngoc Minh PHAM ; Chung Thanh NGUYEN ; Minh Van HOANG ; Andy H. LEE
Journal of Preventive Medicine and Public Health 2019;52(2):101-108
OBJECTIVES:
To objectively determine and compare the physical activity (PA) levels of adults newly diagnosed with type 2 diabetes (T2D) and adults without T2D in Vietnam using an accelerometer.
METHODS:
A total of 120 participants with newly diagnosed T2D and 120 adults without T2D were recruited from a large hospital in Hanoi, the capital city of Vietnam. All participants wore an ActiGraph GT3X accelerometer for at least 5 days, including 1 weekend day. Freedson cut-off points were used to estimate different intensities of PA. In addition, comparisons between groups were made with respect to achieving the World Health Organization (WHO) and International Diabetes Federation (IDF) recommended PA guidelines.
RESULTS:
Men with T2D had significantly lower levels of PA than men without T2D. The respective multivariable-adjusted mean values of daily step count, daily light-intensity, moderate-intensity, and moderate-to-vigorous-intensity PA were approximately 14%, 19%, and 22% lower in the men with T2D than in their non-T2D counterparts. However, women with T2D accumulated a greater number of steps per day than women without T2D. Only 59.2% of the adults with T2D met the minimum recommended level of PA (WHO and IDF), compared to 74.2% of adults without T2D (p<0.05). After adjusting for potential confounders, participants with T2D experienced 50.0% significantly lower odds of achieving PA recommendations.
CONCLUSIONS
Vietnamese men with T2D were less physically active than those without T2D, and adults with T2D were less likely to meet PA guidelines. The results suggest a need for integrating PA into the self-management of this chronic condition.