2.Isolation, extraction and determination of struture and biological effects of plumbagine from Plumbago zeylanica L., Plumbaginaceae
Pharmaceutical Journal 1999;274(2):14-15
From the roots of Vietnamese Plumbago zeylanica L. was isolated plumbagin. Its struture was elucidated by spectral methods in comparison with literatural data. Plumbagin showed high antibacterial activity, high inhibition of vasopermeability and can be applied for therapeutic uses.
Naphthoquinones
;
Biological Sciences
;
Pharmaceutical Preparations
3.Investigation on mechanism and drug kinetic release of sodium diclofenac microgranules
Pharmaceutical Journal 2001;298(2):16-19
The aim of this research is to investigate the mechanism and kinetics of drug release from the core and coated pellets containing sodium diclofenac. Avicel was found to be a good excipient to prepare matrix-type pellets. The drug release could be sustained up to 12 hours. the rate of drug release was fit to Higuchi's model. The microphotograph revealed that the drug release was controlled by the diffusion from the isoluble matrix. The drug release was sustained up to 24 hours. The rate of drug release was fit to Higuchi's model, too. The mechanism of drug release was determined to be the diffusion from insoluble matrix and through the insoluble membrane.
Diclofenac
;
Pharmacokinetics
4.Study on determination of relationship between releasing rate in vitro and absorption rate in vivo of sodium diclofenac 100mg tablets LA
Pharmaceutical Journal 1999;370(8):21-24
The in vitro correlation of sustained release sodium diclofenac 100mg capsule was characterized. Correlation at level A was established between the rate of in vitro release and that of in vivo absorption. Correlation coefficient was found at 0.9705. This correlation coefficient was found at dissolution test used in this research could be applied for quality control of the capsule. The results of the research also showed that the absorption in vivo was suitable for once-a-day dosage form.
Diclofenac
;
Methods
5.Treatment of symblepharon by transplantation of human amniotic membrane
Journal of Vietnamese Medicine 1998;225(9, 10):6-9
We have been performed amniotic membrane transplantation in 18 patients (20 eyes) with 23 operations (3 eyes were regrafted). One month after operation, 90% of the eyes had exellent result, 10% were good. Three months following the transplantation of amniotic membrane, 10 of 17 eyes had excellent result, in 4 of 14 eyes, the symblepharon was reduced. 6 months after the procedure showed that 9 of 14 eyes had excellent result and only 1 eye had recurrence. The sudy showed that human amniotic membrane is good material for reconstruction ocular surface in severe symblepharon. In the eyes with successful transplantation, ocular surface was covered with a soft, thin membrane with vascularization as natural conjunctiva. The material can be easily taken at anytime. The procedure can be applied in every ophthalmological department of provincial hospitals.
Amnion
;
Transplantation
6.The primarily results of the treatment of the thyroid cancer by NaI-131 in Cho Ray hospital
Journal of Vietnamese Medicine 1998;6(2):89-94
An evaluation of 114 patients with ages of 17-74, and thyroid cancer treated by NaI-131 was carried out. Patients were classified according to the pathological anatomy, surgery, radioactive dosage and results of the treatment. The rounds of the treatment and efficacy of therapy in patients with metastatisis were also evaluated.
Thyroid Neoplasms
;
Therapeutics
7.Health status and working environment with visual display terminal users
Journal of Medical and Pharmaceutical Information 2003;0(5):28-30
Health status and working environment with visual display terminal users. The aim of this study was to investigate the relationships between health status (musculoskeletal problems and eyes discomfort) and the condition of work with visual display terminal (VDT). It was carried out using a self-administered questionnaire with two groups:VDT-user (group A:103 workers) and non. VDT user (group B:114 workers). Result: The temperature, humidity, air velocity in working room were good. The noise was higher in comparision with standard of Vietnam. The prevelences of musculoskeletal complaints in various body parts were neck (46.6%), low back (45.63%) shoulder (74.75%), wrist (57.28%). Risk of musculoskeletal complaints were more related to unfavorable working postures. Hand and wrist problems were more affected by repetitive movements. Prevalence of visual complaints was tiredness of eyes: 80.85%, eyes-ache 75.23%
Health
;
Environment
;
Musculoskeletal Diseases
8.Study on isolation of two components with biological activities from the Species of sponge Dysidea cinerea collected from Ha Long maritime area
Pharmaceutical Journal 2005;0(1):10-12
Dys-1 and Dys-2 compounds were isolated and determined structure from extracts of n-hexane and dichloromethane of sponge Dysidea cinerea by normal and reverse phases of silica gel column chromatography. Dys-1 is a white crystallized agent. Through data and reference materials, the agent is determined as Isofucosterol (24-Stigmasta-5, 24(24')-dien-3β-ol). Dys-2 compound is a crystallized agent with crystal of white needle form. The compound is determined as 5, 8- epidioxycholest-6--en-3-ol. It is cyto-toxic against three tumor cell lines in human such as epithelium cancer, liver cancer, and uterus membrane cancer
Porifera
;
Chromatography
9.The progress and immunity response to HIV/AIDS in Cao Bang and the struggle against this epidemic
Journal of Practical Medicine 2003;439(1):19-22
Cao Bang is a mountainous province in North frontier, with a population of 482.839 persons in 12 districts and towns, 186 communes. The first case of HIV infection was detected in 1997 and in Nov.2002 there were 577 cases. The most common patients are young persons (79,53%). 95,66% are men . The education for HIV/AIDS control was developed continuously in mass media but it was not proper, the couselling and self-examination was low efficacy. The care, management and treatment for HIV/AIDS patients were limited. It must strengthen the quality of HIV/AIDS control education and profession practice. For HIV/AIDS control a proper policy and big ressources are necessary
HIV
;
Acquired Immunodeficiency Syndrome
;
Immunity, Cellular
10.To review 250 cases of large corneal transplantation in 1985-1997 year period
Journal of Practical Medicine 2004;480(5):57-59
From the year 1985 – 1997, 250 cases of corneal transplatation were reviewed. The diameter of grafted cornea varied from 8-15mm, among them 113 cases of graft larger than 10mm. After the operation, visual acuty was improved in almost patients. In the case of internal therapy is impossible, this surgery is the only approach to save the eyeball, moreover, the optical function was restored significantly. In the case of progressive infection, which is not responded to the therapy, threatening the eyeball corneal transplantation must be indicated early.
Corneal Transplantation
;
Case Reports
;
Epidemiology