1.Cleaning and Health
Journal of Environment and Health 1992;0(02):-
The sanitary habitation and office are very important for human health, so cleaning is an absolutely necessary part in our living. Although cleaning presents a substantial perceived benefits for our living, there are still some risks for our health. Except for the exposures to dust and other particulate matter suspended during cleaning activities, the main health problem caused by cleaning is the cleaning products. The main hazard composition of cleaning products, air pollution, inhalation pathways, health adverse effects and the measures for reducing the exposures to indoor air pollution caused by cleaning were reviewed in this paper.
2.Effect of Tegafur,Gimeracil and Oteracil Potassium Capsules on peripheral blood TPS,sMICA,HIF-1αand Her-2 in advanced cervical cancer
Chinese Journal of Biochemical Pharmaceutics 2016;36(6):82-84
Objective To investigate the effect of Tegafur, Gimeracil and Oteracil Potassium Capsules ( TS-1 ) on peripheral blood tissue polypeptide antigen (TPS), soluble MHC class I chain-related molecules A (sMICA), hypoxia-inducible factor-1 (HIF-1α) and human epidermal growth factor receptor 2 ( Her-2 ) in the treatment of patients with advanced cervical cancer.Methods 80 cases with advanced cervical cancer were selected and divided into two groups, 40 cases in the control group were treated with routine clinical therapy, 40 cases in the experimental group were treated with TS-1.Tumor markers, TPS,sMICA,HIF-1αand Her-2 were compared before and after the treatment.Results Compared with the control group, the levels of tumor antigen TA-4,carcinoembryonic antigen (CEA) and squamous cell carcinoma antigen (SCCA) in the experimental group were lower (P<0.05); the TPS, HIF-1, sMICA and Her-2 were lower (P<0.05), and the total effective rate in the treatment group was higher (P<0.05).Conclusion TS-1 has a obvious clinical efficacy in the treatment of advanced cervical cancer.It is speculated that the possible mechanism may reduce the serum tumor marker levels via reducing the TPS and SMICA, HIF-1 alpha, HER-2 levels.
3.Control of Sediment Phosphorus Release in Lakes Adding Chemical Reagents
Mingzhu ZHU ; Ying XU ; Huang LI
Journal of Environment and Health 2007;0(08):-
Objective To study the inhibit efficiency of lake sediment phosphorus release by adding chemical reagents and to provide the technical basis for the comprehensive management of city lake.Methods In May 20,2008,Mochou Lake upper sediment and water samples were collected.The phosphorus forms of sediments,total phosphorus(TP),NaOH-P,HCl-P,inorganic phosphorus(IP),organic phosphorus(OP) were analyzed and the pH value and content of TP in water samples were determined.Each water(250 ml)-sediment(10 g) system was respectively added by 0-1 000.0 mg/L of Ca(OH)2,2.0-10.0 mg/L of A12(S04)3 and 0-25.0 mg/L of FeCl3.The pH value and content of TP in water were determined,then the control rate of TP release were calculated.Results The pH values were between 7.6-8.0,TP content was 2.0 mg/L in water of Mochou Lake.The contents of TP,HCl-P,NaOH-P,IP,OP were 2 187.06,1 383.89,526.48,1 910.37 and 276.69 mg/kg respectively.With the increase of Ca(OH)2 concentration,pH value of water increased rapidly,content of TP showed a decreasing trend,control rate of TP release was increased.With the increase of A12(SO4)3 or FeCl3 concentration,pH value of water declined slightly,content of TP showed a decreasing trend,control rate of TP release was increased.Conclusion Ca(OH)2,A12(SO4)3,FeCl3 can significantly inhibit the phosphorus release of sediments in Mochou Lake.
4.Effect of He-Ne Laser Irradiation on Proliferation and Differentiation of Rat Embryo Midbrain Nerve Cell.
Mingzhu YANG ; Li DONG ; Yang BIAN
Journal of Medical Research 2006;0(02):-
Objective To study the effect of He-Ne laser at lower power on proliferation and differentiation of embryo midbrain nerve cell.Methods The embryo midbrain nerve cell of rat embryo were randomly divided into one control group and three experimental groups.The cells in experimental groups were respectively irradiated at different time:3 min(A组),6 min(B组),10min(C组),each day.After ten days,we counted the concentration rate and determined the content of protein and the amount of superoxide dismutase(SOD)and malonyldialolehyde(MDA).Results The concentration rate of group A and of group B significantly increased than that of the control group(P
5.Application of Thin Layer Chromatograph-Fluorescent Method in Quality Control of Herbal Preparations
Ling LI ; Mingzhu LIU ; Weiming XU
Chinese Traditional and Herbal Drugs 1994;0(05):-
A thin layer chromatograph-fluorescent method was used to assay content of scopoletin in Erycibe obtusi folia Benth.. The method showed that it not only can minimize analytical errors in thin layer scan and column contamination in HPLC,but also eliminated mutual interference of components in the preparation. It provides a good assay technique for quality control of hebal preparations. The method was carried out on thin layer plates of silica gel H(40?)with benzene-ether (1. 1: 1 )as the developer,at an excitation spectrum of 347nm,fluorescence spectrum of 420nm and a temperture of 25??1℃.The method showed good linearity(r= 0. 9998, n = 5)in the range of 0.08~0. 40?g/?l of scopoletin and the average recovery was 98. 52 % ~ 102. 67 % with RSD
6.The Application of Noninvasive Central Blood Pressure Detection in Blood Pressure Management and Vessel Function Assessment of Hypertension.
Mingzhu LI ; Yue LIU ; Min LI ; Hua JIANG
Chinese Journal of Medical Instrumentation 2015;39(3):219-221
OBJECTIVESTo explore the significance of noninvasive central blood pressure detection in blood pressure management and vessel function assessment of hypertension.
METHODSA total of 348 subjects were recruited in the study and A-pulse CASP software were derived to measure the parameters of CASP and vessel function. The recruited subjects were divided into different groups for analysis according to age and disease.
RESULTS(1) CASP in hypertension group were both higher than those in normal group, while RAI and PRT lower. (2) Hypertensive patients of which brachial blood pressure were controlled have lower CASP and RAI than those above the level. (3) Hypertensive patients whose brachial blood pressure were controlled have significantly higher CASP than normal subjects.
CONCLUSIONSCentral blood pressure is more reflective of actural blood pressure and vessel function. Enhanced control of CASP in hypertensive patients contributes to improving vessel compliance.
Blood Pressure ; Blood Pressure Determination ; methods ; Humans ; Hypertension ; diagnosis ; Software ; Vascular Resistance
7.Application of assessment criteria for thoracic surgery health education in the health education to patients undergoing thoracic surgeries
Li LIU ; Mingzhu XIN ; Min WANG ; Jinbo LI ; Huiying QIN
Modern Clinical Nursing 2013;(3):66-69,77
Objective To study the effect of assessment criteria for thoracic surgery health education in the health education to patients undergoing thoracic surgeries.Methods One hundred and forty patients undergoing selective surgeries were evenly divided by their registration sequence into the control and experiment groups:The former received routine health education and the latter the health education based on thoracic surgery health education criteria.The effects of the health education were assessed by self-designed recognition evaluation criteria for thoracic surgery health education.Results The experiment group was significantly better than the control in terms of health-related knowledge,health belief and health behaviors,except operative approach,anesthesia method and intraoperative medication(all P<0.05).Conclusions The assessment criteria for thoracic surgery health education are helpful for the nurses to perform health education purposefully and pertinently.The criteria are also applicable clinically for the nursing administers to carry out health education assessment.
8.Effect of ultrasound-guided intervention with methotrexate combined with lauromacrogol on uterine wall thickness and menstrual recovery time in patients with uterine scar pregnancy
Mingzhu LI ; Li ZHANG ; Bei FENG ; Bin ZHU
Chinese Journal of Primary Medicine and Pharmacy 2021;28(4):528-532
Objective:To investigate the effects of ultrasound-guided intervention with methotrexate combined with lauromacrogol on uterine wall thickness and menstrual recovery time in patients with uterine scar pregnancy.Methods:Sixty patients with uterine scar pregnancy who received treatment in Jinhua Wenrong Hospital, Jinhua Central Hospital, and Yiwu Maternity and Children Hospital from February 2019 to February 2020 were included in this study. They were randomly assigned to receive either uterine artery embolization treatment ( n = 30, control group) or ultrasound-guided interventions with methotrexate combined with lauromacrogol ( n = 30, study group). The success rate of treatment, uterine wall thickness at the scar, menstrual recovery time, hospitalization time, hospitalization expenses, incidence of adverse reactions, serum levels of beta-human chorionic gonadotropin (β-HCG) and high sensitivity C-reactive protein (hs-CRP) after 7 days of treatment and uterine wall thickness before and after treatment were compared between the study and control groups. Results:After treatment, the success rate of treatment in the study group was significantly higher than that in the control group [96.67% (29/30) vs. 70.00% (21/30), χ 2 = 7.680, P < 0.05]. Before treatment, there were no significant differences in β-HCG and hs-CRP levels between the control and study groups ( t = -0.197, 0.197, both P > 0.05). After treatment, serum level of β-HCG in the control and study groups was significantly decreased ( t = 22.803, 10.233, both P < 0.01), and serum level of hs-CRP in the control and study groups was significantly increased ( t = -16.357, 7.854, both P < 0.001) compared with before treatment. After treatment, there were no significant differences in serum β-HCG and hs-CRP levels between the control and study groups ( t = 20.413, -20.306, both P < 0.05). After treatment, the incidence of adverse reactions in the study group was significantly lower than that in the control group [6.67% (2/30) vs. 30.00% (9/30), χ 2 = 5.455, P < 0.05). After treatment, menstrual recovery time, hospitalization time and hospitalization expenses in the study group were shorter or less than those in the control group ( t = 5.080, 5.398, 7.599, all P < 0.05). There was no significant difference in the thickness of uterine wall at the scar site between the two groups ( t = -1.045, P > 0.05). Conclusion:Ultrasound-guided intervention with methotrexate combined with lauromacrogol for treatment of uterine scar pregnancy can effectively increase the success rate of treatment, promote the restoration of menstruation, shorten the length of hospital stay, and is highly safe.
9.The Relationship between the Bacterial Vaginosis and 8 Putative Periodontal Pathogen Infection
Yuhua LI ; Mingzhu ZHANG ; Yi PENG ; Jie XU ; Yanqing SHUI
Journal of Kunming Medical University 2016;37(9):9-13
Objective To investigate the relationship between the bacterial vaginosis and 8 putative periodontal pathogen infection.Methods A total of 48 patients with bacterial vaginosis were collected and 47 healthy female patients were selectedin the control group.Vaginal secretion and subgingival plaque were obtained from the study group and the control group.The presence of Porphyromonasgingivalis (P.g),Tannerella forsythia (T.f),Treponemas denticola (T.d),Prevotell intermedia (P.i),Prevotella nigrescen (P.n),Peptostreptococcus micros (P.m),Fusobacteriumnucleatum (F.n) and Campylobacterrectas (C.r) was detected by DNA extraction and PCR method.Simultaneously,all the patients underwent a clinical periodontal examination of the teeth in community periodontal index,including plaque index (PLI),bleeding on probing (BOP),probing depth (PD) and clinical attachment loss (CAL) Results The prevalence of periodontal disease,PLI,BOP and CAL in the study group was significantly higher than in the control group (P<0.05) and the PD had no statistically significant difference between the 2 groups (P>O.05).The 2 groups were both detected 8 putative periodontal pathogens in the vaginal secretion and the subgingival plaque samples.The detection ratio of T.dfrom both the vaginal secretion and subgingival plaque samples was significantly higher in the study group than that in the control group (P <0.05),and other 7 pathogens showed no statistically significant difference (P >0.05) Conclusion The prevalence of periodontal disease was higher among the bacterial vaginosis patients.The 8 putative periodontal pathogens were normal flora in the subgingival plaque and vaginal secretion.Td might be relevant to the pathogenesis of bacterial vaginosis.
10.Cleaning and Disinfecting Effect of Digestive Endoscope by Mall Disinfection Center
Ting LI ; Mingzhu QIANG ; Chune XU ; Yuehong CHEN
Chinese Journal of Nosocomiology 2006;0(07):-
OBJECTIVE To analyze the cleaning and disinfecting effect of digestive endoscope by the Mall disinfection center for endoscopes.METHODS Fifty-six pieces of endoscopes were cleaned and disinfected by the Mall disinfection center,and checked randomly. An other 50 endoscopes were treated as control group.All pieces were taken the biological inspection.RESULTS The qualification rate of lumen disinfection was 100% in test group,and 92% in control group(P