1.Ramus colli nervi facialis dissect in the surgical management of benign parotid tumor
Mingyue LI ; Wei ZHANG ; Ning LIU
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(06):-
OBJECTIVE To study the feasibility and security of parotidectomy for parotid benign tumor by tracing cervical branch to expose facial nerve. METHODS Parotid benign tumor of 87 patients were studied.We exposed facial nerve by tracing main facial nerve branch、buccal branch、marginal mandibular branch and cervical branch in parotidectomy for parotid benign tumor and observed the function of facial nerve after operation.RESULTS The number of patients traced by main facial nerve branch- buccal branch、marginal mandibular branch and cervical branch group were 10、8、28 and 41 respctively,and the percentage of facial nerve injury after operation were 30%、37.5%、46.4%and 24.3%.The percentage of facial nerve injury was statistically different between the marginal mandibular branch group and the cervical branch group(P
2.Obesity and cancer
Mingyue LIU ; Fucai ZANG ; Wei TANG
Journal of International Oncology 2013;40(7):501-503
In recent studies,obesity is a risk factor for a variety of cancers,including breast cancer and colorectal cancer.Obesity can regulate the tumorigenesis and development of cancer by some factors,such as insulin and insulin-like growth factor-1 (IGF-1),leptin,fat cytokines and hormones.Understanding the relationship between obesity and cancer can provide a new perspective for the prevention and treatment of cancer.
3.Effect of donepezil hydrochloride on the Calpain Ⅰ-Cdk5 pathway expression in the hippocampus of mice with vascular dementia
Tianjun WANG ; Wei JIN ; Jingfang LANG ; Mingyue FAN ; Peiyuan LU
Chinese Journal of Behavioral Medicine and Brain Science 2013;22(10):873-876
Objective To investigate the effect of donepezil hydrochloride on the expression of Calpain Ⅰ-Cdk5/p25 pathway in the hippocampal CA1 area by cerebral ischemia and reperfusion in mice.Methods Mice were divided into model group,sham-operated group and donepezil-treated group.The expression of Calpain Ⅰ in hippocampal CA1 area was measured by immunohistochemistry staining respectively at 4,6 and 8 weeks post cerebral ischemia and reperfusion.Western blot was used to evaluate Cdk5 and p25 protein expression.Results The abilities of learning and memory performance was damaged significantly at 4,6 and 8 weeks after surgery compared to sham-operated group (P< 0.05).The expression of Calpain Ⅰ of model group were (0.098 ± 0.009),(0.129 ±0.01),(0.116 ± 0.01),which were higher than that of sham-operated group (0.03 ± 0.003),(0.031 ± 0.003),(0.029 ±0.003) and there was significant difference (P < 0.05).The expression of Cdk5 in model group was (0.54 ± 0.05),(0.73 ± 0.07),(0.7 ± 0.06),which were higher than that of sham-operated group (0.23 ±0.02),(0.31 ± 0.02),(0.33 ± 0.02) and there was significant difference (P < 0.05).The expression of p25 in model group was (0.44 ± 0.04),(0.51 ± 0.04),(0.55 ± 0.06),which were higher than that of sham-operated group(0.19 ± 0.02),(0.24 ± 0.02),(0.2 ± 0.02) and there was significant difference (P < 0.05).The expression of Calpain Ⅰ of donepezil-treated group was (0.041 ± 0.004),(0.054 ± 0.004),(0.046 ± 0.003),which were lower than that of model group.The expression of Cdk5 was (0.28 ± 0.02),(0.33 ± 0.03),(0.38 ± 0.02),and expression of p25 was (0.26 ± 0.02),(0.25 ± 0.03),(0.21 ± 0.02),which were lower than that of model group respectively(P < 0.05).Conclusion Donepezil hydrochloride probably improve the learning and memory abilities by reducing the expression of Calpain Ⅰ and Cdk5/p25.
4.Study on significance of international educational reform of TCM
Mingyue LI ; Bo CHEN ; Wei WANG ; Zelin CHEN ; Yi GUO
International Journal of Traditional Chinese Medicine 2014;(7):647-649
With the process of internalization of traditional Chinese medicine(TCM) accelerating increasely, intensive study on international educational reform of TCM is significant. This article elaborates importance of international educational reform of TCM from development situation of Tianjin University of Traditional Chinese Medicine, combined with regional characteristics, find that intensifying the reform and expanding the opening up of international education of TCM is an Important Channel of international development of Tianjin, a reflection of national willpower, a corollary of adapting to the development trend of the economic globalization and an inevitable requirement and powerful guarantee of internalization of TCM. Therefore, we hold that international educational reform of is imperative to achieve the internalization of TCM.
5.The exploration of pulse-taking teaching of international students
Mingyue LI ; Yilan XU ; Bo CHEN ; Yi GUO ; Wei WANG
International Journal of Traditional Chinese Medicine 2015;(6):558-559
Pulse-taking, as one of the four diagnostic methods of inspection, auscultation and olfaction, inquiry and pulse-taking, can fully embodies the characteristics of traditional Chinese medicine. Pulse-taking is the teaching key point for the international students. However, because the pulsetheory and literature is quite profound and abstract and there is a long distance between the class teaching and clinical practice, the teaching of pulse-taking is also the difficult point for the international students. Therefore, the pulse-taking teaching should focus on the interesting teaching, the culture of traditional Chinese medicine of pulse, image teaching and practice training.
6.Universities of traditional Chinese medicine should value the construction of clinical teaching and training team
Mingyue LI ; Yi ZHANG ; Hongxia ZHANG ; Wei WANG
International Journal of Traditional Chinese Medicine 2015;37(10):928-929
Clinical practice training is a interim curriculum of basic courses and clinical courses, medical university and hospital, which is an important part of medical education system. Clinical practice training teachers, as the main subject of teaching activity, is a key in guaranteeing a better teaching quality. Therefore, we should attach great importance to the construction of clinical practice training teachers, renewal of the idea of clinical practice training, training system and measures of clinical practice training teachers and the improvement of the management of clinical practice training
7.The application of double pedicle blood supply pectoralis major myocutaneous flap in reconstruction of laryngeal and hypo pharyngeal defect after carcinoma resection.
Wei ZHANG ; Mingyue LI ; Ning LIU ; Fangwen CHEN ; Qingzhi MENG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(7):589-592
OBJECTIVE:
To explore the application of double pedicle blood supply pectoralis major myocutaneous flap in reconstruction of laryngeal and hypo pharyngeal defect after carcinoma resection.
METHOD:
All the patients received initial treatment. Pectoralis major myocutaneous flap was Applied in one-stage reconstruction in 22 cases of laryngocarcinoma and hypopharyngeal carcinoma with post-operation defect. During operation, pectoral branches of thoracoacromial vessels and branch of lateral thoracic vessels were reserved and prepared to be double pedicle vessel fascia bundle without muscle at the beginning part, rearched to defect area through subclavian tunnel. After operation, it is necessary to closely observe the subcutaneous swelling, quantity and color of the drain and others of neck surgery area to exclude the occurrence of surgical hematoma. When there is suspicion, do timely exploration.
RESULT:
Pectoralis major myocutaneous flaps of 22 patients were all survived. Pharyngeal fistula occurred in 2 cases and was cured by change of dressing. Twenty-one cases received radiotherapy after operation without secondary flap necrosis. After follow-up of 6 months to 24 months, one case of roll repairment of circumferential defect in cervical esophagus,found to have anastomotic stenosis 8 months after radiotherapy and then underwent gastrostomy treatment,the other 21 cases showed good recovery of swallowing function. Among 13 cases with laryngeal function reserved, only 1 case wearing tube and the extubation rate was 92.3% without communication barriers, no patient died in the short follow-up period.
CONCLUSION
For double pedicle blood supply pectoralis major nyocutaneous flap, blood supply are fully guaranteed and does not require complicated equipment to observe and monitor the flap blood supply after operation, it is important to exclude factors that may lead to muscular flap necrosis to ensure the survival of pectoralis major myocutaneous flap.
Esophagus
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surgery
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Fistula
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pathology
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Humans
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Hypopharyngeal Neoplasms
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surgery
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Laryngeal Neoplasms
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surgery
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Larynx
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surgery
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Myocutaneous Flap
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Pharynx
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pathology
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surgery
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Reconstructive Surgical Procedures
8.Investigation of serum minerals levels in elderly population in Tianjin
Ziwei LI ; Guang LYU ; Xuan WANG ; Wei LIU ; Mingyue ZHANG ; Guowei HUANG
Tianjin Medical Journal 2015;(2):193-195
Objective To investigate the levels of 8 minerals that are related to human health in serum of elderly popu?lation in Tianjin and to provide evidence based guidance for scientifical and rational dietary. Methods Venous blood was collected from 714 elderly people and the levels of 8 minerals were examined by inductively coupled plasma-mass spec?trometry (ICP-MS). Results The percentage of the elderly people who are short of at least one mineral was up to 92.7%. The percentages of deficiency in serum zinc, manganese, magnesium, chrome, iron, calcium, copper, selenium are 79.3%, 73.4%, 58.5%, 42.4%, 39.8%, 23.0%, 1.5%and 0.6%respectively . The level of Ferrum in men’s serum is higher than that in women, while the levels of calcium, chrome and copper in men’s serum are lower than those in women. Conclusion The level of the minerals is generally low in the elderly population from Tianjin and ways were needed in improving dietary.
9.Clinical Observation of Electroacupuncture at Baihuanshu (BL30) and Huiyang (BL55) for Chronic Prostatitis
Mingyue YANG ; Jian YING ; Junxian LI ; Siyou WANG ; Minjie ZHOU ; Wei ZHANG
Shanghai Journal of Acupuncture and Moxibustion 2014;(10):913-915
Objective To observe the therapeutic efficacy of electroacupuncture at Baihuanshu (BL30) and Huiyang (BL55) for chronic prostatitis. Method Ninety patients were divided into an acupuncture-medication group and a Chinese medication group, 45 in each group, to respectively receive electroacupuncture at Baihuanshu and Huiyang plus oral administration of Chinese medication, and single Chinese medication treatment, 4 weeks as a treatment course. The therapeutic efficacy was evaluated by adopting the Chronic Prostatitis Symptom Index by National Institutes of Health (NIH-CPSI). Result The general score of NIH-CPSI dropped in both groups after intervention (P<0.05), while the decrease in the acupuncture-medication group was more significant (P<0.05), and it had a significantly higher therapeutic efficacy than the Chinese medication group (P<0.05). Conclusion Electroacupuncture at Baihuanshu and Huiyang can significantly improve the symptoms of chronic prostatitis, and it’s superior to oral administration of Chinese medication in comparing the clinical efficacy.
10.A 3D-ultrasound imaging system based on back-end scanning mode.
Jian QI ; Yimin CHEN ; Mingyue DING ; Chiming WEI
Chinese Journal of Medical Instrumentation 2012;36(4):235-238
A new scanning mode is proposed that the front-end of the probe is fixed, while the back-end makes fan-shaped, scanning movement. The new scanning mode avoided ribs drawbacks successfully. Based on the new scanning mode a 3D-Ultrasound Images System is accomplished to acquire 2D data of fetusfetus fetusfetus phantom and livers and kidneys, to demonstrates the effectiveness of the new scanning mode.
Fetus
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Humans
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Imaging, Three-Dimensional
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Kidney
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Liver
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Phantoms, Imaging
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Ultrasonics
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instrumentation
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methods