1.Epidural ropivacaine for postoperative pediatral analgesia
Chinese Journal of Primary Medicine and Pharmacy 2005;0(02):-
0.05).Motor block with ropivacaine was recorded earlier than that with bupivacaine(P0.05).Conclusion Ropivacaine is superior to bupivacaine in postoperative analgesia and in motor recovery in children undergoing subabdominal surgery.
2.Expression of iNOS mRNA prevented cardiac allograft vasculopathy after heart transplantation
Naishi WU ; Wangfu ZANG ; Mingyu ZHANG
Chinese Journal of Organ Transplantation 2003;0(01):-
Objective To study the prevention of cardiac allograft vasculopathy (CAV) post-transplant through the expression of iNOS mRNA. Methods Rat model of heterotopic heart transplantation (Abdomen) was developed and recipients were injected with Cyclosporin A at abdomen in the meantime of receiving L-arginine (iNOS mRNA group) and inhibitor of iNOS (L-NAME group) according to grouping. Plasma content of NO_3-, the expression of iNOS mRNA in coronary ~artery of transplanted heart and the radio of tunica intima/tunica media thickness (I/M) were assayed after ~operation . Results The plasma content of NO_3-and the expression of iNOS mRNA in coronary ~artery of transplanted heart in iNOS mRNA group were obviously higher than those in control group and L-NAME group during 2 to 4 weeks after operation. The ratio of I/M in iNOS mRNA group was ~lower than that in control group and L-NAME group 4 weeks after operation. Conclusion The ~expression of iNOS can promote the synthesis of NO and prevent CAV development.
3.Research advances in serum biomarkers for early diagnosis of hepatocellular carcinoma
Mingyu ZHU ; Jie CHEN ; Xinxin ZHANG
Journal of Clinical Hepatology 2014;30(10):1091-1093
Hepatocellular carcinoma (HCC)is a disease with high incidence and mortality and has become a serious threat to human health. So far,none of the available markers can be used alone for early diagnosis of HCC.Recently identified serum markers with potential clinical value for early diagnosis of HCC are summarized,and their diagnostic sensitivity and specificity,as well as their applications in assessment of progression of the disease,are reviewed.It is suggested that alpha -fetoprotein should be used in combination with other serum markers to achieve accurate diagnosis of HCC at early stages.
4.Influence of stress regulation on bone healing of lengthened zone:an experimental study
Huaqing YANG ; Kunzheng WANG ; Mingyu ZHANG
Orthopedic Journal of China 2006;0(18):-
[Objective]To explore the effects of axial stress regulation on healing of lengthened callus.[Method]Tibiaes of 40 rabbits divided into 2 groups were lengthened with circular external fixator.X-ray bone density and histology tests were performed.[Result]The X-ray showed lengthened callus was different after operation.In the control group,lengthened center had a serial callus and cortex had not formed,in the experimental group lengthened center had serial cortex and ttransfixial medullary cavity expects serial callus.[Conclusion]Axial stress regulation and periodicity continue to shortened micromovement stress may promote healing after bone lengthening.
5.Blood Lead Levels of Children in Rural Areas of China
Juan QIN ; Mingyu DING ; Jinliang ZHANG
Journal of Environment and Health 2007;0(12):-
Objective To evaluate Chinese rural children's blood lead levels (BLLs) and identify its distribution features and to provide data for policy development to the prevention of rural environmental lead pollution. Methods The papers on rural children's BLLs published from 1994 to Oct, 2008 were collected by using CNKI's (China National Knowledge Infrastructure) Chinese Journal Full-test Database and other ways. The papers which were eligible for the following criteria were reviewed:(1) BLLs measured by atomic absorption spectroscopy (graphite or others) or inductively coupled plasma-mass spectrometry; (2) strict quality control; (3) no local lead pollution sources in the areas where the screened subjects live in; (4) children aged from 0 to 14 years old; (5)sample size more than 40. Results Analysis on the included 32 papers indicated that, the mean BLLs of Chinese rural children between 1994 and 2008 was 74.93 ?g/L ( range:41.14-193.54 ?g/L)and 19.32%( range:2.2%-43%) of the subjects had BLLs higher than 100 ?g/L. The rural children’s BLLs changed from 87.53 ?g/L to 71.16 ?g/L after the use of lead free gasoline in 2000 in China, which were both lower than the general children's BBLs before 2000 and after 2001. The children in Beijing city and Shandong province showed the highest mean BLLs , with 99.16 ?g/L and 92.13 ?g/L respectively; while the children in Jilin province and Hebei province showed the lowest levels, with 41.14 ?g/L and 56.14 ?g/L respectively. The comprehensive analysis of 18 papers indicated that the mean BLLs in rural areas and urban areas were 77.90 ?g/L and 87.24 ?g/L respectively ( u=3.73, P
6.Anatomically reconstruction of medial patellofemoral ligament with grafted dual-bundle semitendinosus for recurrent dislocation of the patella
Yang LIU ; Jiang ZHENG ; Mingyu ZHANG ; Xian ZHANG ; Yunping ZHOU
Chinese Journal of Orthopaedics 2012;32(2):111-115
Objective To investigate the effect of recurrent patella dislocation by grafting dual-bundle semitendinosus to anatomically reconstruct of medial patellofemoral ligament(MPFL)under arthroscopy.Methods From January 2006 to January 2010,29 cases(31 knees)with recurrent dislocation of the patella were performed arthroscopic surgery,including 11 males and 18 females(20 knees)with an average age of 22 years(range,16-32).The key point of surgery was reconstruction MPFL with dual-bundle free autogenous semitendinosus by using two anchors and bone groove to fixed on the patella,and using the interference screw to fixed on the femur.Adjusting the patella reset under arthroscopy.Tibial tubercle were transferred to inside in 5 cases.All patients were followed up for an average of 14 months(ranging 9-22).The imaging evaluation included congruence angle,lateral patellofemoral angle and lateral shift.The clinical therapeutic effect was evaluated with International Knee Documentation Committee(IKDC),Lysholm and Tegner scores.Results The fear test was negative after operation.There was no redislocation and fracture of the patella during follow-up.The congruence angle,lateral patellofemoral angle and lateral shift were 5.65°±2.23°,3.52°±2.63° and 0.25±0.46 respectively at the final follow-up.The mean IKDC,Lysholm and Tegner scores were 93.20±5.33,93.02±6.08 and 6.58±0.87 respectively at the final follow-up.All were showed statistically significant differences compared with preoperation(P<0.05).Conclusion It is demonstrated that there was a reliable short-term effect to treat recurrent patella dislocation by grafting dual-bundle semitendinosus to anatomically reconstruct of MPFL under arthroscopy.
7.Application of MR-cine in evaluation on functional dyspepsia
Mingyu ZHANG ; Jincheng LI ; Ying LAI ; Kailiang CHENG ; Mengchao ZHANG
Journal of Jilin University(Medicine Edition) 2016;42(2):385-389
Objective:To explore the value of MR-cine for assessment of the duodenum peristalsis in the patients with functional dyspepsia.Methods:25 patients with functional dyspepsia were selected according to the diagnostic criteria of RomeⅢ of functional gastrointestinal disorders (FGIDs)as case group and 25 cases of healthy volunteers who had been screened out in clinic were used as normal control group. After fasting for 8 h,supine position was performed.1.5TGEHDxMR was used to scan the coronal,axial and oblique coronal fast steady state precession (FIESTA)sequence of gastric and duodenal descending part.The images of 5 and 15 min after drinking 600 mL mannitol solution (concentration 2.5%)were collected and sent to MR AW4.4 workstation.The duodenal motility in the patients with functional dyspepsia was measured by recording the times of duodenum and measuring and calculating the percentage occlusion of duodenum contractions (PDC). Results:After drinking mannitol, the oblique coronal scan of all subj ects clearly displayed the anatomical structure and peristaltic wave of descending part of duodenum. After drinking 5 and 1 5 min of mannitol,the peristaltic wave frequencies in case group were lower than those in normal control group. The descending duodenum PDC of the patients in case group was significantly lower than that in normal control group (P<0.01)5 min after drinking. The PDC in normal control group 15 min after drinking was lower than 5 min (P<0.05);the duodenal PDC 15 min after drinking of mannitol had no statistical difference between case group and normal control group (P>0.05).Conclusion:MR-cine can evaluate preliminarly the duodenum peristalsis of the patients with functional dyspepsia. The diagnosis of FGIDs can be further studied by using the noninvasive MR-cine examination technique.
8.Neuronavigator-assisted microsurgical resection of glioma located in cerebral functional areas
Guohui SU ; Zhixiong LIU ; Lei HUO ; Chuntao LI ; Mingyu ZHANG
Journal of Central South University(Medical Sciences) 2017;42(5):542-545
Objective:To evaluate value of neuronavigator-assisted microsurgery of glioma located in cerebral functional areas.Methods:Patients with glioma located in cerebral functional areas were underwent operation in Xiangya Hospital.Of 64 patients,34 patients were performed neuronavigator-assisted microsurgery,and 30 were underwent routine surgical operation.Results:The neuronavigator-assisted microsurgery group showed high complete resection rate with low neurological deficit and cerebral edema compared with the routine surgical group (P<0.05).Conclusion:Neuronavigator-assisted microsurgery is effective and characterized by accurate location,personalized operative incision design,and higher rate of tumor resection.
9.Design and realization of image acquisition system for Philip Tomoscan AV CT
Libo ZHANG ; Benqiang YANG ; Lijuan ZHOU ; Mingyu ZOU
Chinese Medical Equipment Journal 2004;0(08):-
Objective The images of CT Equipment without DICOM interface are stored by means of film all along,and they can't be digitally stored,shared,retrieved,integrated to diagnostic reports.This paper introduces a method to capture images,mainly focus on the image capture and crop technology.Methods The hardware is composed of Philip Tomoscan AV CT,PC,OK_RGB20B image capture card,foot switch.The software is programmed by Microsoft Visual C++6.0,OK_RGB20B SDK and GDI+ Class Library on Windows 2000 operating system.Results The system can capture the CT image successfully,and make the images stored and shared permanently.Conclusion This method is a valuable clew for capturing images from other types of non-DICOM-based medical equipment such as ECT,X-ray,Ultrasound,Endoscope and so on.
10.Research of 2D Medical Image Magnification
Libo ZHANG ; Benqiang YANG ; Lijuan ZHOU ; Mingyu ZOU
Chinese Medical Equipment Journal 1989;0(04):-
Objective To find a programming method of magnifying two-dimentional medical image for clearer view and more precise diagnosis. Methods The software was programmed by using Microsoft Visual C++6.0 and GDI+ Class Library on Windows 2000 operating system. Results The software could magnify the medical images with high quality and definition. Conclusion This method is valuable for medical image digital post-processing.