Objective To investigate status of the intravenous use of antibiotics in outpatients and emergency patients of a tertiary first-class hospital, and provide a reference for developing management measures in next step. Methods By a retrospective method,all the prescriptions using antibiotics by intravenous administration in outpatients and emergency department patients from a tertiary first-class hospital in 2013 were extracted from the hospital information system. The categories of antimicrobial agents,proportion of intravenous use of antimicrobial drugs,ranking of the antibiotic consumption sum and defined daily dose,and the top 10 clinical departments or wards intravenously using antimicrobial drugs were chosen to analyze. The data in 2014 were extracted as a comparison. Results Outpatients and emergency department patients respectively used 8 categories 31 kinds and 8 categories 30 kinds of intravenous antimicrobial drugs, with high consumption of cephalosporins and restricted antimicrobials such as sodium cefoxitin.Intravenous use of antimicrobial drug prescription proportion in emergency department is higher than that in outpatient department. Conclusion After intervention in 2014, antibiotic consumption is effectively controlled as compared that in 2013. But management should be strengthened and appropriate interventions should be taken to ensure the use of intravenous antibiotics in a safe,effective and economical manner.

Objective To observe the effect of E light combined with 595 nm pulsed dye laser in patients with erythromelanosis follicularis of face and neck. Methods The clinical data of 44 patients with erythromelanosis follicularis of face and neck from 2015 to 2017 in Dalian Dermatosis Hospital were retrospectively analyzed. Among the patients, 22 patients were treated with 595 nm pulsed dye laser (control group) and 22 cases were treated with E light combined with 595 nm pulsed dye laser (treatment group). Efficacy was assessed 1 month after treatment, including telangiectasia, pigmentation and follicular papule. Results The total effective rates of telangiectasia, pigmentation and follicular papule in treatment group were significantly higher than those in control group: 86.4% (19/22) vs. 68.2% (15/22), 54.5% (12/22) vs. 9.1% (2/22) and 50.0% (11/22) vs. 13.6% (3/22), and there were statistical differences (P＜0.05). No significant adverse reactions occurred during and after treatment in 2 groups. Conclusions E light combined with 595 nm pulsed dye laser is better and safer than 595 nm pulsed dye laser alone in the treatment of erythromelanosis follicularis of face and neck.