Innovative Experiment Competition of Preventive Medicine is a significant constitution of Guangdong Undergraduate Technique Competition of Preventive Medicine. Without the constriction of majors, students participate in group with 3 people, design their own experiments around the hot spots and practical problems in public health area and are awarded according to the grades of the experiment design and thesis defence. The most topics in the first and the second competitions are about environmental hygiene and occupational hygiene, and the infectious diseases are attracting increasing attention. More and more topics combine the method of experiment with investigation. Some tactics are also suggested that innovation, view of general population, autonomy and investigation should be included in topic selection for this contest.