1.A COMPARATION OF ANTIMALARIAL EFFECT OF TWENTY FOUR CHEMICAL COMPOUNDS IN FOUR DAY SUPPRESIVE TEST IN MICE AND IN CULTURE
Mingxian ZHOU ; Xingqing PAN ;
Chinese Pharmacological Bulletin 1987;0(01):-
The antimalarial effects of 24 chemical compounds on Plasmodium yoelii in mice and on Plasmodium falciparum in culture were observed . The results from both tests for most compounds are parallel or comparable, except few compounds such as Hydroxyurea and Lincomycin.What suitable methods may be used for preliminary screening of antimalarials are discussed.
2.The investigation and analysis of pension models of the aged in the urban and rural of Xi'an city
Chinese Journal of Practical Nursing 2014;30(18):16-19
Objective To investigate the intentions of pension mode of the aged in the unban and rural of Xi' an,and analyze the possible influential factors in old persons' choices of pension modes.Methods The purposive sampling method was used to survey the old persons about their pension intentions by questionnaire,and the collected information underwent statistical analysis.Results Among 317 old persons aged from 60to 91 years old investigated in the study,145 cases were from urban and 172 from rural area.Most old people intended to choose self-pension mode,family pension mode and community pension mode.Only few people chose institution pension mode.Their favorite pension mode was family pension mode,and institution pension mode was the last one to choose for old people.Community pension mode should be developed mostly in their opinion,and self-pension mode must be reduced.Some essential variables had significant influence on their choices of pension models,such as living in urban or rural,occupation,age,marriage,the incomes per month,family support,habitancy and so on.The result of logistic analysis showed that some other variables had no obvious influence on their pension intentions.Conclusions Old people in Xi'an prefer family pension mode mostly.Community pension mode is the one which has a good developing prospect.Social pension mode need to be intensified.
3.The diagnostic values of color ultrasound to the stenosis of extracranial carotid arteries
Mingxian TAN ; Jie ZHOU ; Shengli CHEN
Journal of Clinical Neurology 2001;0(05):-
Objective To investigate the diagnostic values of color ultrasound to the stenosis of extracranial carotid arteries.Methods Color ultrasound examination and digital subtraction angiography(DSA)were performed in 145 patients with ischemic cerebravascular disease.The sensitivity and specificity of color ultrasound for the stenosis of extracranial carotid arteries were analyzed according to the golden standard of DSA results.Results The sensitivity and specificity of color ultrasound for stenosis of carotid bifurcation,subclavicular artery and vertebral artery were 96.8%,80.6%,60.0% and 98.7%,33.3%,89.0%.The accuracy of color ultrasound for stenosis of carotid bifurcation,subclavicular artery and vertebral artery were 93.0%,92.8% and 82.1%.Conclusion Color ultrasound examination are effective for the diagnosis of carotid bifurcation sterosis,and less effective for the diagnosis of the subclavicular and vertebral artery stenosis because of the poor sensitivity.
4.Infection Rate of HBV among High School Graduates in Jingjiang City of Jiangsu Province
Mingxian ZHOU ; Jian WU ; Lifang XU
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(06):-
Objective To investigate the positive rates of HBsAg and abnormal rates of Alanine aminotransferase among high school graduates in Jingjiang city.Methods HBsAg were detected by ELISA and ALT was detected by rate assay among 20 988 high school graduates during 2004—2007 in Jingjiang city.Results The HBsAg positive students were 1754.The total positive rate of HBsAg was 8.36%.The positive rate of HBsAg of male(9.46%)was higher than that of female(6.95%).The HBsAg positive rate of rural students(9.44%)was higher than that of urban students(7.28%).HBsAg positive rates of urban students showed a decreasing trend during 2004—2007,the rates were 9.31%,8.08%,6.74% and 5.24%,respectively(P0.05).There were 155 cases(8.4%)with increased ALT among 1754 HBsAg positive students.Conclusion The total positive rate of HBsAg among high school graduates in Jingjiang city from 2004—2007 was 8.36%.The HBsAg positive rate of male students was higher than that of female.The HBsAg positive rate of rural students was higher than that of urban students.8.4% students were found ALT abnormal.We should intensify Hepatitis B vaccine in time to prevent the spreading of HBV.
5.Effect of hierarchical intervention on hypertension prevention and control among middle-aged and elderly people in rural area
Mingxian GUO ; Yadong ZHOU ; Xianzhen ZHANG ; Wanxia YAO
Chinese Journal of Modern Nursing 2017;23(26):3371-3374
Objective To discuss the effect of hierarchical intervention on hypertension prevention and control in rural area,so as to improve awareness rate and health promoting behaviors about the hypertension disease among middle-aged and the elderly in rural area. Methods A gradually deepening intervention scheme was implemented hierarchically of levels of entire population,prehypertension group and hypertension group from March 2014 to February 2016. Results After the intervention, score of health-promoting lifestyle in the research group was(132.86±16.70),significantly higher than that in the control group(113.72±20.86),and also within the group,higher than before the intervention (108.47±16.161)(P < 0.01). Value of blood pressure,regular behavior of measurement and body mass index in the research group were all better than those in the control group and before the intervention (P < 0.05). Awareness rate of knowledge related to hypertension in the research group was significantly higher than those in the control group and before the intervention(P<0.01). Conclusions The gradually deepening hierarchical health education intervention among middle-aged and elderly people in rural communities can prevent and control hypertension by improving awareness rate of the disease and help developing health promoting behaviors.