1.Curative effect observation of Xuesaitong Injectiion for cerebral infarction
Chinese Traditional Patent Medicine 1992;0(04):-
AIM:To study the curative effect of Xuesaitong Injection (total notoginsenoside) on cerebral infarction.METHODS: 60 patients are divided into two groups at random. The treatment group was treated with Xuesaitong Injection (10mg in 250mL of 0.9% NS by IV infusion). The control group was treated with Danshen Injection (16mL in 250mL of 0.9% NS by IV infusion). Once a day for 28 days.RESULTS: The total effective rate of Xuesaitong Injection group was 80.0%. There were little bad reaction reported. The total effective rate of Danshen Injection was 66.7%. The curative effect of treatment group is superior to the control group ( P
2.Application of the emergency nursing pathway in acute myocardial infarction patients and effect evaluation
Chinese Journal of Practical Nursing 2011;27(29):1-3
Objective To observe the effect of the emergency nursing pathway on acute myocardial infarction patients.Methods From December 2009 to December 2010,86 cases of AMI patients were classified into the observation group and the control group with 43 cases in each group.The observationgroup was treated with emergency nursing pathway and the control group was treated with traditional nursing.The time of lying in bed,hospitalization time,disease knowledge,complications and patients satisfaction degree between the two groups were compared.Results The time of lying in bed,hospitalization time in the observation group were significantly shorter than those in the control group,disease knowledge scores were significantly higher than those in the control group,and complication rate was significantly lower than that in the control group.The patients' satisfaction degree in the observation group was significantly higher than that in the control group.Conclusions Application of emergency nursing pathway in acute myocardial infarction patients can shorten time of lying in bed and hospitalization time,lower complication rate,improve patients' satisfaction degree,which is worthy of being applied in clinic.
3.Experimental Research on Adjuvant Arthritis Treated with Different Combinative Herbal Mixture
Xuguang JIANG ; Mingxia JIANG ; Xuening JING
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(02):-
Objective To observe the effect of Chinese herbs most used in rheumatoid arthritis such as diaphoretics (ephedra), wind-expelling herbs (monkshood), blood activating drugs (angelica) and compound mixture in treating adjuvant arthritis, and study the compatibility law. Methods AA rats in groups were treated with ephedra-cinnamon twig mixture, monkshood-aconitum mixture, angelicachuanxiong mixture, herbs compound mixture, low dose herbs compound mixture which is composed of above-mentioned herbs and semblable function herbs. Compare with normal group, model group, tripterygium wilfordii hook (TWH) group, TNF-? and PGE2 level of hindpaw were measured by ELISA and spectrophotometer. Weight index of immune organs were measured to study the effect of different functional ingredient groups and complex on immune function. Result The hinderpaw PGE2 level and TNF-? level of model group was higher than normal group (P
4.Clinical study on treatment of bronchiolitis with theophylline
Mingxia HUANG ; Ping JIANG ; Zhengqiong FANG
Chinese Pediatric Emergency Medicine 2008;15(z1):12-15
Objective To explore whether theophylline has clinic effects of treatment on bronchiolitis in children. Methods 128 children with bronchiolitis in our hospital were divided into the experiment and the control at random, in the meantime, grouped into the severe and the mild according to their condition. The children in the control were used traditional methods. The children in the control were taken theophylline, as well as used traditional methods. All patients in our hospital were checked up pulmonary function, alkyladenine glycosylase in trachea secretion, serum interleukin 8, cytotaxonomy in trachea secretion on time, after the third day and the 7th day. Results The pulmonary function and cytotaxonomy of the patients in the experiment were more improvement than that of the control. Their alkyladeniue gtycosylase in trachea secretion and serum interleukin 8 were very lower than that of the control. The cure rate in the mild and the severe of the experi-ment were higher than that of the control. Conclusion Administrating theophyUine by oral can improve the pulmonary function, relax a block of the small trachea, and raise the cure rate of patients with bronchiolitis.
5.Progress of JMJD5 in tumors
Ling QI ; Mingxia JIANG ; Yanjing LI
Cancer Research and Clinic 2021;33(4):311-313
JMJD5 belongs to the protein family of JMJD and is closely related to tumorigenesis. JMJD5 plays a carcinogenic role in some tumors, such as oral cancer, prostate cancer, breast cancer, colon cancer and atypical meningiomas, JMJD5 promotes the proliferation, migration and invasion of cancer cells. However, JMJD5 not only plays a carcinogenic role in some tumors, but also plays an anticancer role. For example, in bladder cancer, JMJD5 inhibits the metastasis of bladder cancer; in liver cancer, on the one hand JMJD5 promotes the replication of hepatitis B virus (HBV), and on the other hand it inhibits the growth of cancer cells; in lung cancer, on the one hand JNJD5 promotes the proliferation of cancer cells, and on the other hand it inhibits the metastasis of cancer cells by promoting the stabilization of microtubules. This article will focus on the mechanisms of JMJD5 in tumors, in order to provide a new target for tumor prevention and treatment.
6.Application of Group Teaching in Rehabilitation Nursing
Hongwei XU ; Zhimei JIANG ; Xiangying KONG ; Yinping SONG ; Mingxia JIANG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(6):599-600
Objective To investigate the effects of group teaching in rehabilitation nursing. Methods 55 nursing students were dividedinto control group and experiment group. The control group received traditional teaching and the experiment group received group teaching.Questionnaire and examination performance were used to evaluate the effects of group teaching in the teaching of rehabilitation nursing. ResultsThe scores were significantly higher in the experiment group than in the control group (P<0.01). The questionnaire showed that groupteaching can stimulate their interest and intrinsic motivation for learning, enhance their understanding and application of knowledge, cultivatetheir self-learning ability, analysis and problem-solving abilities, interpersonal communication skills and spirit of collaboration. At thesame time, the implementation of group teaching helps both teaching and learning. Conclusion Group teaching can improve the teaching effectivenessof rehabilitation nursing.
7.Prospective Study of Use of Alginate Calcium Dressing after Surgery of Anal Fistula
Ka LI ; Lili JIANG ; Mingxia LI ; Zengrong CHEN
Chinese Journal of Bases and Clinics in General Surgery 2008;0(08):-
0.05).The incidence of skin allergy was significantly different between two groups(29.69% vs.60.94%,P
8.Discussion on enlightenment education for children with cerebral palsy
Ping LIN ; Hongwei XU ; Yanan WANG ; Mingxia JIANG ; Qihui ZHOU
Chinese Journal of Rehabilitation Theory and Practice 2003;9(4):208-209
目的探讨启蒙教育对提高脑瘫患儿智力和注意力集中能力的作用。方法组织启蒙教育班,对25名脑瘫患儿通过游戏、手工、学儿歌、音乐、辨色、认识方位等多种形式开发智力 ,培养注意力集中能力。结果经启蒙教育后,患儿智商比教育前明显增高(χ2=4.13,P<0.05),注意力集中能力明显增高。结论启蒙教育可提高脑瘫患儿的智力和注意力集中能力,促进患儿的全面康复。
9.Correlation of sarcopenia and metabolic risk factors
Yu WANG ; Mingxia JIANG ; Qi XU ; Mengmeng WU ; Yinan ZHOU ; Xinyuan DONG ; Jinfeng ZHENG
Journal of Medical Postgraduates 2017;30(2):181-185
Objective Sarcopenia and metabolic syndrome share similar pathophysiological mechanisms. The aim of this study was to investigate the prevalence of sarcopenia among health examination population, and to analyze the relationship between sar-copenia and blood pressure, blood glucose, uric acid and lipids. Methods Physical examination data of 1191 healthy persons in the medical examination center of the hospital from Mar 2011 to Jun 2011 were collected. The weight, skeletal muscle, body fat, body mass index ( BMI) , waist circumference,body fat percentage, waist-hip ratio and visceral fat area were analyzed by human body compositionanalyzer and the prevalence of sarcopenia was observed. At the same time, triglyceride (TG), total cholesterol (TC), high density lipo-protein-cholesterol ( HDL-C ) , low density lipoprotein-cholesterol ( LDL-C) , uric acid and fasting blood glucose were also detected. Results The prevalence rate of sarcopenia of the subjects was 5.21%, and the highest incidence was found in ≥60 years group( 11.11%) . The prevalence rates of overweight and obesity were 33.8% and 10.2%, respectively. The prevalence of sarcopenia is grad-ually higher along with increasing BMI. The prevalence rates of sarcopenia of overweight and obesity subjects were 5.47% and 26.23%, respectively. Compared with the normal control group, the level of weight[(66.34±11.75)kg vs (76.71±12.84)kg ], BMI[(23.37± 3.13) vs (28.05±3.66)], body fat percentage[(25.33±6.06)% vs (36.76±4.47)%], waist circumference[(83.19±9.56)cm vs (95.45±13.74)cm] and visceral fat area[(88.96±29.74)cm2 vs (136.91±25.56)cm2] were higher in the sarcopenia group (P<0.05). Compared with the normal control group, the incidence of systolic blood pressure[(125.59±30.04)mmHg vs (139.39±19.79) mmHg], diastolic blood pressure[(75.82±11.95)mmHg vs (82.34±10.96)mmHg ] TG[(1.56±1.12)mmol/L vs (1.98±1.72)mmol/L] and uric acid[(313.75±83.07)mmol/L vs (335.55±96.07)mmol/L] were higher in the sarcopenia group (P<0.05). Compared with the normal subjects, the detectable rates of abnormal diastolic blood pressure, fasting blood glucose, uric acid, and LDL-C were increased in the sarcopenia, obesity and sarcopenia combined with obesity subjects (P<0.05). The odds ratio of abnormal systolic blood pressure, diastolic blood pressure, uric acid, and LDL-C increased in the sarcopenia, obesity and sarcopenia combined with obe-sity subjects using logistic regression analyses after correction of gender and age. Conclusion The sarcopenia may have some con-nection with metabolic risk factors. Early detection of sarcopenia can help to distinguish people predisposed to metabolic syndrome, and it has important significance for prevention of chronic disease.
10.Short tandem repeat analysis for diagnosing complete hydatidiform mole and coexisting fetus: a casereport and literature review
Yanping LU ; Hui LIU ; Mingxia YE ; Shufang JIANG ; Jing CHENG ; Huijun YUAN ; Yali LI
Chinese Journal of Perinatal Medicine 2012;15(7):429-432
Objective To investigate the parental origin for a rare case of complete hydatidiform mole and coexisting fetus and to discuss its diagnosis and differential diagnosis.Methods Tissues from the fetus,mole and placenta were collected and pathology analysis and chromosome analysis were done.The DNA from the fetus,mole and parents' peripheral blood leukocytes was amplified with five short tandem repeat (STR) markers (D4S2460,D18S488,D21S2039,DXS1205 and DYS219) at the same time to confirm the parental source of the hydatidiform.Results (1) Casereport:A 27-year-old woman,gravida 1,para 0,was found high risk for neural tube defects at 20 weeks of gestation.At 24+5 weeks of gestation,ultrasound examination demonstrated a normal fetus,a normal placenta and a huge mass with a multicystic appearance attached to the placenta with an obvious demarcation.The fetus died at 26 weeks of gestation.Serum human chorionic gonadotropin-β(β -hCG) level decreased obviously during the first two weeks after artificial induction,but elevated at the third week,and β-hCG titers fell to normal after 2 courses of chemotherapy.Fetus autopsy showed no structure abnormality.Histopathologic examination of the hydatidiform showed swelling of chorionic villi with hyperplasia of the trophoblast and formation of central cisterns suggesting of a twin pregnancy consisting of a complete hydatidiform mole and coexisting fetus.(2) Genetic analysis:The karyotype analysis of the normal placental villi was 46,XY; the cell cultures of fetal cartilage tissue and hydatidiform were failed.STR analysis showed that the fetus was diploid from biparental source;the mole was androgenetic source.And the mole had locus both from Y and X chromosome of the father,so it was heterozygous.It was suggested that this case was derived from one single oocyte fertilized with three spermatozoas.Conclusions STR analysis could be used to confirm the diagnosis of complete hydatidiform mole and coexisting fetus and to find the pathogenetic rnechanism.