1.CT Manifestation of Adenoid Tonsil Hypertrophy in Children (An Analysis of 25 Cases)
Journal of Practical Radiology 2001;0(08):-
Objective To summarize the CT manifestations of adenoid tonsic hypertrophy in children and evaluate clinical significance.Methods Twenty boys and 5 girls were diagnosed with adenoid tonsil hypertrophy,the ages from 13 to 15 years.CT scanning of nasal pharynx with 3 mm were performed in all cases.Results The thicken of adenoid tonsil hypertrophy was 13 mm to 25 mm. Sector shape of the lesion was presented in 14 cases,strip shape in 9 cases ,irregular shape in 2cases,eustachian tube stenosis or disappearance in 6 cases.The complications included:hypertrophy of tonsil in 13 cases,nasosinusitis in 11 cases,hypertrophic conchae in 21 cases,mastoiditis in 2 cases.Conclusion CT scan can accurately show adenoid tonsil hypertrophy and irregular stenotic nasopharyneal meatus and complications. CT will be the first choice in examination of adenoid tonsil hypertrophy before operation.
2.Clinical study of CT virtual endoscopy in diagnosing polyps of the gallbladder
Mingwu LOU ; Weidong HU ; Tao YANG
Chinese Journal of Radiology 2001;0(08):-
0.05). CTVEGB could more correctly demonstrate the surface details of polyps which were viewed in a 3D fashion in any projection than ultrasound. CTVEGB corresponded well with color Doppler ultrasound and operation and pathology in demonstrating the size, configuration and location of the lesions. Conclusion CTVEGB is a noninvasive and accurate procedure, which has a important value in clinic applications.
3.Lumbar bone mineral content in Shenzhen women by quantitative computerized tomography
Mingwu LOU ; Xiurong WANG ; Shunxing WANG ; Jingbo WANG ; Guangfu YANG
Chinese Journal of Tissue Engineering Research 2005;9(15):200-202
BACKGROUND: Bone mineral content(BMC) can be determined by many methods, which are different in detecting position, clinical significance and differentiation between normal group and people with osteoporosis.OBJECTIVE: To establish a normal BMC standard by observing lumbar BMC with quantitative computerized tomography(QCT) measurement in Shenzhen women, so as to provide basis for clinical prevention and treatment of osteoporosis in the region.DESIGN: Randomized controlled, observational and comparative study taking normal women as subjects.SETTING: Medical imaging department of a hospital at district level.PARTICIPANTS: A total of 120 women aged 30 to 69 years, who received physical examination in the Central Hospital of Longgang district in Shenzhen from September 2000 to March 2002, were enrolled in this study. They were divided into four groups: 30 - 39 age group, 40 - 49 age group, 50 - 59 age group and 60 - 69 age group with 30 in each.METHODS: Trabecular and cortical BMC of lumber bodies(L1-3) were measured with QCT software so as to establish a standard of normal BMC in Shenzhen women and compare it with that of other regions.MAIN OUTCOME MEASURES: The mean BMC in Shenzhen women, and comparison with that of other regions at home and abroad.RESULTS: The results of QCT showed linear correlation between BMC and bone ash weight, which could be expressed by the following linear regression equation: ash weight =0. 92432 × BMC + 39. 0633. Lumbar BMC loss increased with age in Shenzhen perimenopausal women. The annual loss of spongy bone and compact bones was 1.38% and 0. 84%, respectively. BMC of women aged 50 to 59 years was[ (135.31 ± 18.36) mg/cm3], obviously higher than that of women in Changchun city, Beijing city and the United States [(120.21 ±37.40), (116.7 ±26.6), and(119.5 ±27.1) mg/cm3]( t = 2. 002, 3. 383, 3. 636, P < 0.05 - 0. 01 ) . Moreover, BMC of women aged 30 to 39 years was also obviously higher than that of corresponding American women( t = 3.119, P < 0.01 ). No significant difference was found in BMC among women of the other age groups in these regions( P > 0. 05).CONCLUSION: This is the first time in our country to establish a standard of normal BMC in perimenopausal women with QCT measurement, which provides basis for early prevention and treatment of osteoporosis as well as evaluation of prognosis and fracture risk.
4.The study of low frequency fluctuation in the resting state between short-term heroin and methamphetamine abusers after withdrawal
Yang YU ; Mingwu LOU ; Lin LU ; Wenbin LIANG ; Yunxia SHEN
Journal of Practical Radiology 2015;(6):887-890
Objective To investigate the differences of low frequency fluctuation (ALFF)in the resting state between short-term heroin and methamphetamine abusers after withdrawal.Methods Sixteen male short-term heroin abusers and fourteen male short-term methamphetamine abusers were performed the functional magnetic resonance imaging (fMRI).The differences of ALFF be-tween the two groups were performed with preprocessing softwares.Threshold was set to 0.05.Results Compared with metham-phetamine-dependent patients,heroin-dependent patients showed increased ALFF in the left side of the lingual gyrus and the left ton-sil of cerebellum and decreased ALFF in the left side of the brain stem,midbrain and the left side of the cerebellar vermis.Conclusion There are differences between the short-term heroin and methamphetamine abusers in the function of the brain,mainly involving the brain regions associating with cognition and affection.
5.The correlation between MRI features and pathological characterization of ovarian thecoma-fibroma
Jichao ZHU ; Mingwu LOU ; Fangjing ZHANG ; Weidong HU
Journal of Practical Radiology 2014;(8):1344-1347
Objective To analyze the correlation between MRI features and pathological characterization of ovarian thecoma-fibro-ma.Methods MRI manifestations of 21 patients with ovarian thecoma-fibroma proved by pathological diagnosis were analyzed retro-spectively and compared with pathologic findings.Results The 21 cases involved 22 lesions (one patient had bilateral masses of the-cofibroma),including 13 fibrothecoma,4 thecofibroma and 5 fibroma.All lesions presented with well-defined margin,and cystic changes were found in 1 5 cases,7 lesions were solid masses ,1 9 lesions were round or oval masses ,2 lesions were lobulated mas-ses,and 1 lesion was irregular mass.The diameters of tumor ranged from 3.4 to 18.5 cm with mean diameter of 8.9 cm.On MR images,all lesions showed isointense or slight hypointense on T1 WI.On T2 WI,most tumors showed isointense or slight hypoin-tense,along with hyperintense cystic areas in 1 5 lesions,patchy slight hyperintense edema areas in 4 lesions,and homogeneous isointense or slight hypointense in 3 lesions.After contrast enhancement,all lesions demonstrated mild-to-moderate enhancement and delayed progressive enhancement slightly.13 cases associated with varied degrees of pelvic effusion,1 case with thickening of endometrium,and 1 case with endometrial carcinoma.Two patients had a higher level of CA125.Postoperative pathology demon-strated that all lesion were benign.Conclusion The MRI findings of the ovarian thecoma-fibroma are considerably characteristic and indirectly reflect pathology of tumor,thus beneficial to the correct diagnosis of tumor with relevant clinical information.
6.Measurement of prefrontal cortex and hippocampus temperature change with magnetic resonance spectroscopy for heroin addicts
Wenbin LIANG ; Xinjun SUN ; Kun ZHANG ; Yunxia SHEN ; Mingwu LOU
Journal of Practical Radiology 2017;33(4):493-496
Objective To investigate temperature changes in prefrontal cortex and hippocampus of heroin addicts with magnetic resonance spectroscopy (MRS).Methods 18 heroin addicts in the withdrawal state and 18 healthy volunteers (control group) were performed with MRS scan.First, resting-state MRS scan was performed on all subjects, and then did MRS scan again under visual stimulation while subjects were asked to carefully watch the heroin-related cue images.Measurements of NAA of the identified regions (the prefrontal cortex, bilateral hippocampus) were obtained from all subjects.Brain temperatures were calculated by the modified brain temperature-chemical shift equation.Results In resting state, the temperature of prefrontal cortex in heroin addicts group was higher than the control group, the difference was statistically significant (P<0.05),and the brain temperature was positively correlated with total dose of heroin (P<0.05).The prefrontal cortex/hippocampus temperature of heroin addicts group did not showed statistical significance between resting state and visual stimulation state (P>0.05).Conclusion MRS can be used to measure brain temperature noninvasively.Temperature change of brain may be helpful for exploring the mechanism of drug addiction and craving.
7.Experimental Study of the Accuracy of SIEMENS Osteo Software
Mingwu LOU ; Xiurong WANG ; Jingbo WANG ; Guangfu YANG
Journal of Practical Radiology 2001;0(07):-
Objective To assess the accuracy of SIEMENS Osteo software.Methods The mineral content of 20 cadaver lumber bodies(L 1~L 5) was measured by quantitative CT,and compared with bone ash analysis.Results Mineral content and bone ash weight had a linear correlation,which could be expressed by followed regress equation:ash weight=0.92432?BMD+39.0633.The results with quantitative CT method were all lower than that with bone ash analysis (average lower 29.196 mg/cm 3).Conclusion There are some deviations for measuring bone mineral content with this software.The deviation is within the limit of the theory error of single energy quantitative CT.The result of the measurement shoud be accurate after proofread.
8.MRI comparative study of the progressive supranuclear palsy, striatonigral degeneration and Parkinson disease
Wulin WU ; Mingwu LOU ; Xiaoyi WANG ; Weihua LIAO
Chinese Journal of Radiology 2009;43(6):595-599
Objective To provide a reliable differential diagnosis among the progressive supranuclear palsy ( PSP), striatonigral degeneration ( SND ) and Parkinson disease ( PD ) . Methods Conventional MRI data in clinically proved PSP(8 cases), SND(9 cases), PI)( 12 cases)and 12 normal controls were retrospectively analyzed. Midbrain area, pons area, ports diameter and middle eerebellar peduncles width were measured. The ratio of pons area over midbrain area (pons area/midbrain area) was calculated in all patients and normal controls. Then one way ANOVA and a Kruskal-Wallis H test were used for statistical analysis. Results Midbrain area of the PSP group [ (85. 8±12. 0) mm2 ] was the smallest, and there was statistically significant difference ( P < 0. 05 ) comparing with the SND group [ ( 133.2± 8. 4) nun2 ], PD group[ ( 133. 5±10. 8) mm2 ] and the control group [ ( 135.9±7.5 ) mm2 ]. There was no overlapping in the distribution of midbrain area between the PSP group(66.0-98. 2 mm2 ) and SND, PD and normal groups( 116. 2-142. 1, 110. 8-146. 2 and 121.7-145.8 mm2 ). The pons area-midbrain area ratio (P/M) of the PSP group (5.9±0. 8) was the largest in four groups, and there was statistically significant difference ( P < 0. 05 ) comparing with the SN D group ( 2. 9±0. 5 ), PD group ( 3.8±0. 3 ) and the control group (3. 8±0. 3 ). There was no overlapping in the distribution of P/M between the PSP group(5.0-7.2) and SND,PD and normal groups(2. 2-3.5, 3. 3-4. 6 and 3. 2-4. 2). SND group had the smallest P/M, pens area, pons diameter and middle cerebellar peduncles width [ 2.9±0. 5, ( 384. 8±62. 6) mm2 , ( 18. 6±2. 0) nun and( 12. 9±2. 4) mm ] in all groups, and significant difference ( P < 0. 05 ) was found comparing with the PSP group[5.9±0. 8, (500.1±21.8)mm2, (22. 7±1.7)mm and( 16. 3±1. 1) nun],PD group[3.8±0.3, (500.2±25.8)mm2, (23.7±1.0)mm and(16.8±1. 1)mm]and the control group [3. 8±0. 3, ( 508. 8±20. 6 ) mm2, ( 23.2±1.2) nun and ( 16. 4±0. 9 ) mm]. But the PD group and control group had no statistically significant difference in the midbrain area, pans area, pons diameter, P/M and middle cerebellar peduncles width ( P > 0. 05 ). Conclusion MRI measurements helps in the differential diagnosis among PSP, SND and PD.
9.MR quantitative study of cerebrospinal fluid flow in sella region
Weidong HU ; Xiurong WANG ; Shaobin ZHANG ; Mingwu LOU ; Shaojuan WANG
Chinese Journal of Postgraduates of Medicine 2008;31(16):16-18
Objective To quantitatively study the features of cerebromspinal fluid(CSF)flow dynamies in normal sella region in MRI with phase-contrast method.Methods Seventeen healthy volunteers were studied.The CSF flow image in sella region was positioned at the middle sagittal T1WI or T2WI image.This pulse sequence used a encoding velocity of 20 cm/s.The waveforms were analyzed for the maximum flow velocity,flow volume rate and the change of the figures.From the velocity and area measurements on the cine images,mean CSF flow was calculated in millimeters per second and milliliters per cardiac cycle.Results The normal CSF flow of the sella region had two directions which was downward(caudal)flow during thesystolic period and upward(cranial)flow during the diastolic period of the cardiac cycle.The downward and upward peak flow velocity,mean downward and upward flow velocity and mean flow velocity was(1.44±0.99)cm/s,(302.71±248.15)ms,(1.16±0.64)cm/s,(331.00±225.38)ms,(0.49±0.39)cm/s.(0.67±0.44)cm/s,(0.54±O.30)cm/s,respectively.The downward and upward peak flow volume rate.mean downward and upward flow volume rate and mean flow volume rate was (0.014±0.009)ml/s.(0.012±0.006)ml/s,(0.047±0.041)ml/s,(0.053±0.003)ml/s,(0.005±0.003)ml/s,(0.034±0.031)ml/s,respectively.The mean cycle was(775.25±173.06)ms.Conclusion Phase-contrast method in MRI cine is a noninvasive method to study the CSF flow in physiological and pathological conditions for determining the pattern,direction,speed and quantity of the CSF flow.Therefore it is better than other invasive research modalities and has an important value in clinical application.
10.Application research of MR diffusion tensor imaging in diagnosis traumatic axonal injury
Wenbin LIANG ; Zhengwei LIU ; Jiyin RUAN ; Mingwu LOU ; Yunxia SHEN
Journal of Chinese Physician 2014;(7):909-912
Objective To explore the value of MR diffusion tensor imaging ( DTI) in diagnosis of traumatic Axonal injury ( TAI) .Methods Twenty nine patients with traumatic brain injury ( TBI) and matched 22 control subjects were performed with DTI . Fractional anisotropy ( FA) was calculated from semioval center , corpus callosum , internal capsule and pons of controls and TBI pa-tients.According to Glasgow Score (GCS), TBI patients were divided into mild group (GCS≥13) and moderate-severe group (GCS≤12), each group compared with control group in FA value .The correlation between FA values in different regions and GCS score were analyzed in DTI group .Results FA value of semioval center was decreased in mild DTI group ( P <0.01 ) .FA values of semio-val center , corpus callosum , and internal capsule were decreased in moderate-severe DTI group ( P <0.05 ) .The FA values in semio-val center , corpus callosum , and internal capsule were positively correlated with GCS score in TBI group ( P <0.05 ) .Conclusions DTI is sensitive to detect the traumatic axonal injury??Changes of FA value in ROIs can access the severity of axonal injury ?? which ishelpful for diagnosis earlier and improving prognosis.