1.Establishment of Modern Basic Theory of Traditional Chinese Medicine, Part Ⅰ New Concept:Theoretical Premise, Reveal Connotation of Concept Towards Modern Science
Mingqi QIAO ; Sheng WEI ; Haijun WANG ; Peng SUN ; Huiyun ZHANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(2):216-224
Editor's Notes: The basic theory of traditional Chinese medicine is the theoretical foundation of Chinese medicine , modernization of Chinese medicine needs of the modern theory of Chinese medicine urgently . However , it is always the important issues about how modern Chinese medicine theory should be created , and what kind of theory should have been established concerned and explored by domestic and foreign counterparts in tradi-tional Chinese medicine . To lead the development of modern Chinese medicine theory , Modern Basic Theory of Traditional Chinese Medicine series of symposiums are set up specially in the current Review column, and discussed thoroughly and systematically using three consecutive pats respectively. Among them, part I contains 3 articles about new concepts, new theories, new disciplines; part II contains 5 articles about new ideas, new norms, how to clear concept, how to verify hypotheses, why to evaluate theory; part III contains 12 articles about concept of wholism updating, treatment based on syndrome differentiation development, viscera-state doc-trine innovation, pathogeny, etiology, pathogenesis, prevention, principle of treatment, knowledge structure, cogni-tion structure , monographic study , 5-year outlook . Published article on this issue is the first one belong to new concept of part I. In this paper, we want to describe the denotation and connotation of the new concept of the modern basic theory of traditional Chinese medicine from three aspects of a concept: a label , a theoretical definition , and an operational definition learning from the international academic understanding of scientific concepts, demonstrate the necessity of theoretical premise to the research and establishment of the modern basic theory of traditional Chinese medicine and the need to build on , illustrate the inevitable trend toward modern science . The whole article contains profound meaning and a certain breakthrough and innovation. We are expected to cause concerns and discusses of experts and scholars through this article .
2.Correlation between two animal models of state anxiety in Kunming mice: evidence from open field test and light-dark box
Shiguang SUN ; Sheng WEI ; Peng SUN ; Mingqi QIAO ; Huiyun ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(2):101-104
ObjectiveTo explore the correlation between open field test(OFT) and light-dark box (LDB),as two animal models of state anxiety in Kunming mice.MethodsThe behavior of adult,male,Kunming mice in OFT and LDB was recorded by sequence,for five minutes,with a one-week inter-trial interval.The following parameters were evaluated:percentage of time exploring in the OFT central area( OFT-Ctime% ) ; percentage of squares crossing in the OFT central area( OFT-Ccross% ) ; total number of squares crossing in OFT(OFT-Cross) ;total number of rears in the OFT(OFT-Rear) ; number of fecal boli in OFT(OFT-FB) ; percentage of time exploring in the LDB light area( LDB-Ltime% ) ; percentage of squares crossing in the LDB light area( LDB-Lcross% ) ;and percentage of rears in the LDB light area( LDB-Lrear% ) ; transitions between two areas in LDB( LDB-Transition) ; total number of squares crossing in LDB(LDB-Croas) ; total number of rears in LDB(LDB-Rear) ; number of fecal boli in LDB (LDB-FB).Subsequently,factor analysis,cluster analysis and correlation analysis were calculated for these parameters.ResultsFactor analysis and cluster analysis of variances from either OFT or LDB revealed a three behavioral dimensions:anxiety factor ( loaded by OFT-Ctime%,OFT-Ccross% or LDB-Ltime%,LDB-Lcross%,LDB-Lrear% ),activity factor ( loaded by OFT-Cross,OFT-Rear or LDB-Transition,LDB-Cross,LDB-Rear) and emotionality factor(loaded by OFT-FB or LDB-FB).While all the variances from both OFT and LDB in combination were analyzed,it could be seen as five components:' LDB-anxiety factor ( loaded by LDBLtime%,LDB-Lcross% and LDB-Lrear% ),' OFT-anxiety factor ( loaded by OFT-Ctime% and OFT-Ccross% ),'LDB-activity factor (loaded by LDB-Transition,LDB-Cross and LDB-Rear),'OFT-LDB-emotionality factor( loaded by OFT-FB and LDB-FB) and 'OFT-activity factor (loaded by OFT-Cross and OFT-Rear).Good correlation were found between OFT/LDB factors alone and in combination,such as OFT-emotionality factor and LDB-emotionality factor(Pearson =0.383,P<0.05),LDB-anxiety factor and 'LDB-anxiety factor( Pearson =0.989,P<0.01 ),OFT-anxiety factor and 'OFT-anxiety factor( Pearson =0.934,P < 0.01 ),LDB-activity factor and 'LDB-activity factor ( Pearson =0.956,P < 0.01 ),OFT/LDB-emotionality factor and ' OFT-LDB-emotionality factor ( Pearson =0.835,P<0.01 ;Pearson =0.696,P<0.01 ),OFT-activity factor and 'OFF-activity factor( Pearson =0.926,P<0.01 ).ConclusionEither OFT or LDB comprised three behavioral dimensions:anxiety factor,activity factor and emotionality factor; however,it was difficult to establish face validity as a point-to-point concordance between OFT and LDB.Attention should be paid to heterogeneity of animal models when OFT and LDB were in combination as a behavionomics to evaluate anxiolytics in Kunming mice.
3.Data Mining of Factors Associated with Sleep Quality of Anger-out and Anger-in Population Based on FP-Tree Growing Algorithm
Ling ZHANG ; Zhi HAO ; Sheng WEI ; Peng SUN ; Mingqi QIAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(8):1595-1601
This article was aimed to study the factors associated with sleep quality of anger-out and anger-in population based on the frequent pattern-tree (FP-Tree) growing algorithm with data mining. The algorithm of structuring frequent model FP-tree and mining frequent itemsets were designed. The database information scanned was recorded by using FP-Tree growing algorithm through state-trees. The frequent itemsets met minimum support required was generated through reducing the search space of project sets and scanning database only one. The data mining of all factors associated with emotional diseases was actualized. The results showed that factors associated with sleep quality of anger-out and anger-in population were disturbance in respiration, cough or snoring, feeling cold, hot or nightmares. The total time for program analysis was 2 seconds. It was concluded that data mining algorithm based on FP-Tree frequent itemsets can effectively realize the useful information receiving from factors associated with emotional diseases.
4.Cause of Death Related to Medical Disputes in Yancheng Area:A Study of 60 Autopsy Cases
Mingqi PENG ; Rongyu CHEN ; Lan ZHOU ; Kaiqiao ZHANG ; Jiansong SHI
Journal of Forensic Medicine 2014;(2):110-111
Objective To summarize the pattern and main characteristics of fatal cases related to medical disputes in Yancheng area. Methods Sixty fatal cases of medical disputes were retrospectively analyzed to elucidate the annual incidence, characters of distribution of hospitals, gender and age of the decedents, types of diseases, and cause of death. Results Among 60 fatal cases, most cases happened in health clinics of county, township and village. There were more males than females. The major medical specialties in-volved included internal medicine, surgery, gynecology and pediatrics, with the internal medicine specialty having the highest incidence. Conclusion Police institutions have advantages in investigation of these cas-es in their jurisdictions, which could enhance the ability of local medicolegal examination.
5.The Subtle Anatomical Structures of Normal Nasal Bone in MSCT Image and Forensic Identification
Zishen WANG ; Mingqi PENG ; Hua WEI ; Chongliang YING ; Lei WAN
Journal of Forensic Medicine 2014;(3):184-187
Objective To summarize the subtle anatomical structures of the normal nasal bone in mul-ti-slice spiral CT (MSCT) image through the observation of the three-dimensional images. Methods One hundred and twenty volunteers who had no nasal trauma and disease history were collected. The nasal was scanned using MSCT. Raw data was reconstructed into bone window images (slice thickness 0.6 mm, slice interval 0.5 mm), and then the images were imported into Syngo Imaging XS software to recon-struct three-dimensional images and to summarize the nasal bone ’s subtle anatomical structures. Results The subtle anatomy of normal nasal bone generally included four seams, two holes and one edge. The four seams were left and right nasal-maxillary suture, nasal-frontal seam, and internasal suture. The two holes were left and right nasal aperture. The edge of the nasal was the lower edge of the nasal bone. In addition, there was suture bone in internasal suture in some normal nose. The nasal aperture mostly was hole-like, but some nasal apertures were line shape. The nasal edge can be divided into flat type, wave-shaped type, inverted spike type, hook-shaped type and others. Conclusion The anatomy diversity and individual differences in nasal bone are large. MSCT and three-dimensional image reconstruction techniques, combined with the history of trauma could distinguish between the normal anatomy and fractures.
6.Open field test as a method for ethology in Kunming mice: three behavioral dimensions by factor analysis
Shiguang SUN ; Zifa LI ; Peng SUN ; Sheng WEI ; Mingqi QIAO ; Huiyun ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(10):875-877
Objective To explore the behavioral dimensions of the open field test ( OFF),as a method for ethology in Kunming mice.Methods The behavior of adult,male,Kunming mice in OFF was recorded twice,for five minutes,with a one-week inter-trial interval.The following parameters were evaluated by factor analysis:percentage of time exploring in the central area (Ctime%); percentage of squares crossing in the central area (Ccross%) ; total number of squares crossing in the whole apparatus(Cross) ; total number of rears in the whole apparatus(Rear) ; and number of fecal boli(FB).Results There were good intercorrelation and intracorrelation between test and retest for Ctime%,Ccross%,Cross and Rear.Ctime% and Ccross% had significant loadings on “Anxiety” factor ( Loading%:43.34%,48.56% ) ; Cross and Rear loaded on “locomotor-Exploration” factor ( Loading%:27.94%,29.30% ) ; and FB loaded on “Emotionality” factor ( Loading%:21.95%,15.93% ).A good correlation was found between test and retest for anxiety factor and locomtor-exploration factor.Conclusion Open field test,as a method for ethology in Kunming mice,comprise three behavioral dimensions:anxiety factor,OFF-activity factor(locomotor-exploration) and emotionality factor.
7.Theoretical Connotation and Clinical Application with Liver Body Yin and Function Yang
Haijun WANG ; Jieqiong WANG ; Peng SUN ; Sheng WEI ; Mingqi QIAO ; Huiyun ZHANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;17(4):885-890
This paper was aimed to analyze the theoretical connotation with liver bodyyin with function yang, and to explain the physiological and pathological mechanism of body yin and function yang, respectively. The mechanism of its corresponding syndrome and symptoms were described and the composing principle of classical prescription for liver regulation was analyzed. The clinical significance of liver body yin with function yangwas confirmed by clinical cases. This paper argued that the liver ascending characteristics, which is a necessary guarantee for ascendingqi in the human body to adapt to the ascending gas of the world, is the key point to maintain balance of qi ascending and descending in the body. The liver ascending disorder mainly manifested for the excessive ascending and ascending deficiency, which analyzed the pathogenesis characteristic and clinical manifestation of the liver qi ascending disorder. This paper put forward a new view that the liver storing blood referred to the convergence and the conservation properties of the liver, which demonstrated the relationship between liver storing blood and controlling dispersion. It suggested that liver blood convergences liverqi so as not to make liverqi too excessive. The liver storing blood can raise spirit. Liver blood is the source of menstruation, and etc. This paper finally put forward the clinical prescription viewpoint of soothing liver and dropping inverse should raiseyin and gentle liver necessarily, releasing liver should raise liver and nourish blood and clearing away the liver-fire should cool blood and nourishyin. This research had certain clinical value.
8.Exploration of nursing bonus shares method based on competence and post performance
Mei LI ; Yuan WANG ; Lanfeng GUO ; Ailing XIE ; Mingqi PENG
Chinese Journal of Modern Nursing 2016;22(14):2045-2049
Objective To build up one bonus shares method of improvi ng nursing quality in order to simulate nurse′s the inner enthusiasm.Methods The competence model and assessment system were established for one important weight for bonus sharing of competence qualified of nursing staff,competence coefficient and performance assessment.Results The implementation of performance assessment improved nurse′s satisfaction from 76.3% to 89.2%,while the parent′s satisfaction increased from 84.3% to 93.0%(χ2 =1 3.070,9.766;P <0.05).Conclusions The bonus shares method is scientific and reasonable,which can dig out the potential of nursing staff and is worthy of promotion.
9.Implementation and effects of pediatric nurses' ability level system based on post competency model
Yiwen ZHANG ; Mei LI ; Yuan WANG ; Mingqi PENG ; Ailing XIE ; Qian ZHAO
Chinese Journal of Modern Nursing 2017;23(12):1584-1588
Objective To implement pediatric nurses' ability level system based on the construction of pediatric nurses' ability level model and competency index databases and set up nurses' core competency requirements and advanced conditions so as to provide evidences for pediatric nurses′ ability level management. Methods Nurses' core competency requirements and advanced conditions were set up. N1 and N2 certificated of nurses' ability level were implemented in the whole hospital. Satisfaction of nurses and family members of children before and after the implementation were compared.Results A total of 354 nurses applied for N1 and N2 ability level in the whole hospital. A number of 289 out of 354 applications passed the audit and 237 out of 289 applications have been certificated. For N1 level,148 out of 180 (82.22%) applications were certificated. For N2 level, 90 out of 174 applications (51.72%) were certificated. Satisfaction rates of nurses increased from (83.88±11.886) to (89.84±10.740) after the implementation, with a statistically significant difference (t=-5.180,P<0.01). Satisfaction rates of family members developed from 84.27% to 93.01% after the implementation. The difference was statistically significant (χ2=9.766,P<0.05).Conclusions The implementation of nurses' ability level system improves nurses' work enthusiasm and increases nurses' work satisfaction and family members' satisfaction.
10.Qualitative research on job stressors of male nurses in ICU in a children's hospital
Meng LI ; Mingqi PENG ; Mei LI ; Qingxiu CHEN
Chinese Journal of Modern Nursing 2017;23(12):1596-1599
Objective To explore the job stressors of male nurses in children′s hospital, so as to provide evidence for hospital managers in improving occupational status of male nurses and in establishing measures of improving male nurses′ cultivation and development.Methods With the method of phenomenology in qualitative research and purposive sampling used, in April 2016, 10 male nurses in Pediatric Intensive Care Unit (PICU) in a class Ⅲ grade A children′s hospital were deeply interviewed with semi-structure, with the data analyzed and themes extracted.Results The job stressors of male nurses in children′s hospital can be summarized as 4 themes:heavy workload,un-recognition by the crowd,love and marriage difficulties and career development prospect.Conclusions Adverse factors exist in work and life of male nurses in children′s hospital. Healthy development of their career depends on joint efforts made by the society,hospital administrators and the male nurses themselves.