1.Quality-control testing,evaluation and application of X-ray machine's major parameters
Zuhua ZHANG ; Chuanjun WU ; Minglan WU
Chinese Medical Equipment Journal 2004;0(07):-
This paper introduces the testing methods with respect to the major parameters (X-ray tube voltage & current,exposure time,exposure volume)of X-ray machine as well as the testing results evaluation and application. It is proved that quality control of x-ray machine is an important content and technical means as to guarantee quality for radiology department of hospital.
2.Investigation of the cognitive status of nursing of cancer patients among nurses of cardiothoracic surgery department and countermeasures
Fenlan ZHANG ; Minglan CHEN ; Yu DU
Chinese Journal of Practical Nursing 2012;28(16):25-27
Objective To investigate the cognitive status of nursing of cancer patients among nurses of cardiothoracic surgery department,to discuss countermeasures to improve nursing quality of tumor patients of cardiothoracic surgery department. Methods 150 nurses of cardiothoracic surgery department from November 2009 to November 2010 in five hospitals of a certain city were selected as the research object.The elf-made questionnaire about cognition of cancer patients nursing was adopted for investigation.The cognition condition of health education,psychological care,death education,care of cancer pain of 150 nurses was taken for statistics. Results The study showed that 150 cardiothoracic surgical nurses mastered the health education knowledge best,the average score was(88.6 ± 11.3).The knowledge of death related knowledge was the worst,the average score was (64.5 ± 21.6).The differences of mastering degree of psychological care and pain related knowledge level for 5 hospital nurses were quite significant.The differences of psychological care knowledge levels of hospital A and C,D were significant.The differences of care of cancer pain of hospital B and A,E,F were significant. Conclusions Based on the cognitive status of cardiothoracic surgery nurses for nursing of cancer patients,appropriate theoretical and practical training can be adopted in order to improve cognitive level of related knowledge about nursing of cancer patients among cardiothoracic surgery nurses,so that the nursing quality for cancer patients can be improved.
3.A Comparative Study of IQ and MQ of Patients with CVD Involving Different Cerebral Lobe and Basal Ganglia Areas
Cheng CUI ; Tianling ZHANG ; Minglan KANG ; Hong TAO
Chinese Journal of Clinical Psychology 2000;0(04):-
Objective: To measure IQ and MQ of patients with cerebral vascular diseases (CVD) involving different cerebral lobes and basal ganglia areas. To provide useful data for clinical assessment of brain functions with respect to degree and range of IQ and MQ impairments. Methods: 60 cases of localized CVD were confirmed by clinical diagnosis and CT scan. The patients were evaluated by the WAIS-RC and WMS-RC after convalescence. Results: There were reliable differences between patients and normal controls ( P
4.Prevalence and correlation of workplace violence and emotional intelligence among psychiatric nurses
Bangfeng ZHANG ; Minglan XIN ; Qinghua LU
Chinese Journal of Practical Nursing 2019;35(5):325-330
Objective To investigate the prevalence of workplace violence and explore the relationship between workplace violence and emotional intelligence among psychiatric nurses Methods Totally 453 nurses were enrolled from five psychiatric hospitals via regional stratification and clustersampling in Shandong province. The workplace violence frequency scale, emotional intelligence scale were administered. Results The average workplace violence score among psychiatric nurses was (6.64 ± 3.56) points, while the emotional intelligence average score was (3.79 ± 0.37) points. The each dimensions of emotional intelligence were negatively correlated with workplace violence and types of workplace violence among psychiatric nurses(r=-0.496--0.214, P<0.01). Results of hierarchical liner regression showed that self-emotion management, type of ward, emotional awareness, hospital degree, gender could negatively predict workplace violence of psychiatric nurses (R2=0.333,F=44.636, P=0.000). Conclusions Workplace violence is prevalent among psychiatric nurses, and emotional intelligence might have influence on workplace violence.
5.Changes of natural killer cells in peripheral blood in patients with newly-diagnosed type 1 diabetes mellitus
Minglan YANG ; Xiaofang ZHANG ; Li WANG ; Jie GAO ; Bokai WANG ; Jie HONG ; Xiaoying LI ; Weiqing WANG ; Guang NING ; Weiqiong GU
Chinese Journal of Endocrinology and Metabolism 2012;28(6):455-459
Objective To investigate the changes in nunmber and function of natural killer ( NK ) cells in patients with newly-diagnosed type 1 diabetes mellitus.Methods Cell courning was performed in peripheral blood mononuclear cell ( PBMC ) subsets in 43 cases with newly diagnosed type 1 diabetes ( T1D ),14 cases with newly diagnosed type 2 diabetes( T2D ) and 21 cases of normal controls by flow cytometry sorting.And then,isolating and collecting NK cells were performed in T1D patients and normal controls.Real time PCR was performed to evaluate the mRNA expression levels of NK cell activity related genes IFN-γ,perforin,NKp46,and NKp30 in NK cells.Results Compared to normal controls,both the proportion and the absolute counting of NK cells in PBMC from patients with T1D were significantly decreased [( 102±86 )/μl vs ( 355±264 )/μ1,P<0.01],while only the proportion of CD4+ cell were slightly increased( P<0.05 ).No statistical difference was observed regarding CD8+ T cells ( P>0.05 ).mRNA expression levels of NK cell activity related genes perforin and NKp46 in NK cells were remarkably down-regulated ( P<0.05 ),while IFN-γ and NKp30 were not changed compared with normal controls.Conclusions The reduced number and functional deficiency of NK cells may lead to the immune dysfunction in T1D and play an important role in the development of T1D.
6.Effect of early activity on postoperative delirium for patients after craniotomy: an evidence-based protocols
Qiuping GU ; Minglan ZHU ; Jingfen JIN ; Weiwei ZHANG ; Yuan YUAN ; Wei WANG ; Yuping ZHANG ; Gaowei XU
Chinese Journal of Practical Nursing 2021;37(34):2667-2672
Objective:To observe the effect of evidence-based early activity training on postoperative delirium in patients with brain tumor resection.Methods:This study used non-contemporary comparison method, a total of 238 patients admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine in 2019, were included. 121 patients who met the inclusion criteria and signed informed consent after craniotomy during January 1st,2019 to June 31th,2019 were included in the control group, and 117 patients who met the criteria and obtained informed consent after craniotomy during July 1 to December 31,2019, were included in the experimental group. Neurosurgical postoperative routine nursing care were given to the control group. The experimental group received evidence-based early activity training. The incidence of delirium, duration of delirium, Barthel Index (BI), delirium-related adverse events and other indicators of postoperative hospitalization were compared between two groups.Results:The incidence of delirium, duration of delirium and postoperative hospital stay in the experimental group were 9.5%, 2.0 (1,3) days and 7 (5,10) days, lower than 23.3%, 3.0 (1,5) days and 8 (6,11) days in control group, and the differences were statistically significant ( χ2 value was 8.17, Z value were 2.96 and -2.01, P<0.05). BI index 1 week and 1 month after discharge in the experimental group was 90 (85, 90), 100 (100, 100), higher than the control group of 90 (86, 90) and 100 (100,100), with statistically significant difference ( Z values were -2.41 and -2.46, P<0.05), the comparison of adverse events, 0 case in experimental group, 1 case in control group, there was no statistically significant difference ( χ2 value was 0.97, P>0.05). Conclusions:Early evidence-based activities in patients with brain tumor resection can reduce the incidence of postoperative delirium, shorten the duration of postoperative delirium and postoperative hospital stay, and improve the ability of patients to take care of themselves after surgery, which is safe and effective.
7.Practice of multi-campus homogeneous management of outpatient services at a large public hospital
Lili ZHANG ; Xiaoyun YE ; Weiya CHEN ; Minglan ZHU
Chinese Journal of Hospital Administration 2023;39(11):816-820
The homogeneous management of outpatient services at public hospitals with multi-campus is the foundation for promoting high-quality development of hospitals. Since 2013, a large general hospital had implemented a practice of multi-campus homogeneous management of outpatient services based on the hospital′s integrated organizational structure and management system, addressing such issues as weak outpatient service capabilities in the early stages of new campus construction, lack of homogenization in management system implementation, and poor communication between cross hospital services and information. An integrated post management mode was established with multi-post service integration, cross-post personnel flow and unified job standard. An integrated outpatient quality management system was created by the strategy of " one standard" system management, " one platform" service handling, integrated quality monitoring and management, and multi-aspect service experience improvement. The integration of vertical management and flat management were promoted through the committee system, three-level management system, and functional groups. At the same time, this management practice actively leveraged the advantages of the hospital to innovate services, and promoted the interconnection of outpatient service information across hospital areas, to integrate outpatient service positions, work, services, and management across multi campuses. The satisfaction rate of outpatient patients, the pass rate of outpatient medical records, and the on-time visit rate of outpatient physicians had increased from 91.96分, 95.38%, and 91.62% in 2019 to 93.75分, 98.47%, and 93.68% in 2022, as well as the stopping rate of expert outpatient services had decreased from 5.26% to 1.86%. This practice of homogeneous management had achieved good results, so as to provide references for other hospitals to carry out homogeneous management of outpatient services in their campuses.
8.Exploration of common biological pathways for attention deficit hyperactivity disorder and low birth weight.
Bo XIANG ; Minglan YU ; Xuemei LIANG ; Wei LEI ; Chaohua HUANG ; Jing CHEN ; Wenying HE ; Tao ZHANG ; Tao LI ; Kezhi LIU
Chinese Journal of Medical Genetics 2017;34(6):844-848
OBJECTIVETo explore common biological pathways for attention deficit hyperactivity disorder (ADHD) and low birth weight (LBW).
METHODSThei-Gsea4GwasV2 software was used to analyze the result of genome-wide association analysis (GWAS) for LBW (pathways were derived from Reactome), and nominally significant (P< 0.05, FDR< 0.25) pathways were tested for replication in ADHD.Significant pathways were analyzed with DAPPLE and Reatome FI software to identify genes involved in such pathways, with each cluster enriched with the gene ontology (GO). The Centiscape2.0 software was used to calculate the degree of genetic networks and the betweenness value to explore the core node (gene). Weighed gene co-expression network analysis (WGCNA) was then used to explore the co-expression of genes in these pathways.With gene expression data derived from BrainSpan, GO enrichment was carried out for each gene module.
RESULTSEleven significant biological pathways was identified in association with LBW, among which two (Selenoamino acid metabolism and Diseases associated with glycosaminoglycan metabolism) were replicated during subsequent ADHD analysis. Network analysis of 130 genes in these pathways revealed that some of the sub-networksare related with morphology of cerebellum, development of hippocampus, and plasticity of synaptic structure. Upon co-expression network analysis, 120 genes passed the quality control and were found to express in 3 gene modules. These modules are mainly related to the regulation of synaptic structure and activity regulation.
CONCLUSIONADHD and LBW share some biological regulation processes. Anomalies of such proces sesmay predispose to ADHD.
Attention Deficit Disorder with Hyperactivity ; etiology ; genetics ; Gene Ontology ; Gene Regulatory Networks ; Genome-Wide Association Study ; Humans ; Infant, Low Birth Weight
9.Different Characteristics of Psychological and Sleep Symptoms Across Social Media Addiction and Internet Gaming Disorder in Chinese Adolescents- A Network Analysis
Wanling ZHANG ; Liwen JIANG ; Minglan YU ; Rong MA ; Tingting WANG ; Xuemei LIANG ; Rongfang HE ; Chun XU ; Shasha HU ; Youguo TAN ; Kezhi LIU ; Bo XIANG
Psychiatry Investigation 2024;21(7):782-791
Objective:
Previous research has explored a variety of mental disorders associated with Internet Gaming Disoder (IGD) and Social Media Addiction (SMA). To date, few studies focused on the network characteristics and investigated mood and sleep symptoms across SMA and IGD of adolescence at a group-specific level. This study aims to identify different characteristics of IGD and SMA and further determine the group-specific psychopathology process among adolescents.
Methods:
We conducted a cross-sectional study to recruit a cohort of 7,246 adolescents who were scored passing the cutoff point of Internet Gaming Disorder Scale-Short Form and Bergen Social Media Addiction Scale, as grouped in IGD and SMA, or otherwise into the control group. Patient Health Questionnaire-9, Generalized Anxiety Disorder 7-item, and Pittsburgh Sleep Quality Index were assessed for the current study, and all assessed items were investigated using network analysis.
Results:
Based on the analytical procedure, the participants were divided into three groups, the IGD group (n=789), SMA group (n=713) and control group (n=5,744). The edge weight bootstrapping analysis shows that different groups of networks reach certain accuracy, and the network structures of the three groups are statistically different (pcontrol-IGD=0.004, pcontrol-SMA<0.001, pIGD-SMA<0.001). The core symptom of SMA is “feeling down, depressed, or hopeless”, while IGD is “feeling tired or having little energy”.
Conclusion
Although IGD and SMA are both subtypes of internet addiction, the psychopathology processes of IGD and SMA are different. When dealing with IGD and SMA, different symptoms should be addressed.
10.Impact of autonomic nerve function on motor function in patients with post-stroke depression
Minglan ZHANG ; Lingling ZHANG ; Lisha WANG ; Li LIU ; Run GAO ; Jiang RAO ; Wan LIU ; Zi'an XIA ; Chuanwen ZHANG ; Xinxin CHENG
Chinese Journal of Rehabilitation Theory and Practice 2024;30(2):223-231
ObjectiveTo explore the impact of autonomic nerve function on motor function in patients with post-stroke depression (PSD) from the perspective of regional homogeneity (ReHo). MethodsFrom January to December, 2020, a total of 60 inpatients and outpatients with cerebral infarction in the Affiliated Brain Hospital of Nanjing Medical University were divided into control group (n = 30) and PSD group (n = 30). Two groups were assessed using Fugl-Meyer Assessment (FMA), modified Barthel Index (MBI) and Hamilton Depression Scale (HAMD). Heart rate variability (HRV) was measured. Ten patients in each group were selected randomly to undergo resting state functional magnetic resonance imaging (rs-fMRI) to calculate ReHo. ResultsAll HRV indices were lower in PSD group than in the control group (|t| > 2.092, P < 0.05). In PSD group, FMA and MBI scores showed positive correlations with 24-hour standard deviation of normal-to-normal R-R intervals (SDNN), the root mean square of successive differences between normal heartbeats over 24 hours (RMSSD), the percentage of differences between adjacent normal R-R intervals over 24 hours that were greater than 50 ms (PNN50), total power (TP), very low frequency power (VLF) and low frequency power (LF) (r > 0.394, P < 0.05), and showed negative correlations with HAMD scores (|r| > 0.919, P < 0.001). HAMD scores in PSD group were negatively correlated with SDNN, RMSSD, PNN50, TP and VLF (|r| > 0.769, P < 0.001). Compared with the control group, the ReHo increased in PSD group in the right rectus gyrus (142 voxels, t = 6.575), the left medial and paracingulate gyri (204 voxels, t = 4.925) (GRF correction, P-Voxel < 0.005,P-Cluster < 0.05); and reduced in the right cerebellum (191 voxels, t = -6.487), the left middle temporal gyrus (140 voxels, t = -5.516), and the left precentral gyrus (119 voxels, t = -4.764) (GRF correction, P-Voxel < 0.005,P-Cluster < 0.05) in PSD group. ConclusionAutonomic nerve function is related to motor dysfunction in patients with PSD. The modulation of emotional, cognitive and motor brain regions by the autonomic nervous system may play a role in influencing the motor function in patients with PSD.