1.Time Selection of Acupuncture Treatment for Facial Paralysis
Journal of Acupuncture and Tuina Science 2007;5(2):106-108
Objective: To investigate the optimal time for treating facial paralysis with acupuncture therapy. Methods: Eighty-six patients with facial paralysis in different disease durations were treated with same needling technique. Patients of the treatment group at the developing stage were dealt with moderate stimulation, and at the stationary stage and the recovery stage with strong stimulation. Patients of the control group at the developing stage were treated with drugs improving micro-circulation and nerve functions, and glucocorticoids, at the stationary stage and the recovery stage with the same methods as in the treatment group.Results: The cure rate in the treatment group and the control group were 88.1% and 68.2%respectively, and the former has shorter treatment course. Conclusion: Acupuncture therapy has better effect on facial paralysis than routine Westem medicine, and shorter treatment course.
2.Observations on the Efficacy of Combined Acupuncture and Medicine in Treating 50 Cases of Pseudobulbar Paralysis
Journal of Acupuncture and Tuina Science 2006;4(3):150-152
Objective: To investigate the curative effect of combined acupuncture and medicine on pseudobulbar paralysis. Method:The patients were allocated into an acupuncture group of 50 cases and a control group of 48 cases by completely random sampling. The acupuncture group received western medicine combined with acupuncture and the control group received simple Western medicine. Results:The effective rate was 92.0% in the acupuncture group and 62.5% in the control group. There was a very significant difference in curative effect between the two groups(P< 0.01). Conclusion: The curative effect of combined acupuncture and medicine on pseudobulbar paralysis is significantly better than that of simple Western medicine.
3.Clinical Observations on the Treatment of Pseudobulbar Paralysis by Combined Scalp and Body Acupuncture
Journal of Acupuncture and Tuina Science 2006;4(3):153-155
Objective: To investigate the efficacy of scalp acupuncture in combination with body acupuncture for treating pseudobulbar paralysis. Methods: Eighty patients were randomly divided into treatment and control groups, 40 cases each. The control group was treated by the routine method of Western medicine and the treatment group by combined scalp and body acupuncture on the basis of the former. The curative effect was evaluated after treatment in both groups. The influence of the treatment on mean blood velocity(MBV) in anterior, middle and posterior cerebral arteries was observed by transcranial Doppler(TCD) in both groups. Results: The total efficacy rate was 97.5% in the treatment group and 12.5% in the control group. The recovery rate was 75% in the treatment group and 0% in the control group. There was a significant difference between the two groups(P< 0. 01). TCD showed that blood velocity in cerebral arteries was significantly increased and the unbalanced stasis of the right and left cerebral blood flow changed in the treatment group. A comparison of MBV between pretreatment and posttreatment showed P < 0.01. Conclusion: Scalp acupuncture in combination with body acupuncture has a good effect on pseudobulbar paralysis.
4.Modern Progress of Mechanism of Moxibustion Therapy
Junfeng ZHANG ; Yaochi WU ; Minghai SHAO
Journal of Acupuncture and Tuina Science 2006;4(5):257-260
Moxibustion therapy is one of the external therapeutic methods. In the present article, the pharmacological and physical actions of moxibustion therapy, and the effects of moxibustion therapy on immune system, blood circulation, inflammation, and body metaboly were reviewed.
5.Warm-Needling Technique for Peripheral Facial Paralysis
Chuannian WANG ; Jing ZHOU ; Minghai SHAO
Journal of Acupuncture and Tuina Science 2007;5(2):95-96
Objective: To observe the therapeutic effects of warm-needling technique on peripheral facial paralysis. Methods: Warm-needling technique and electroacupuncture were employed to treat 30 cases of facial paralysis, respectively. The same acupoints, Cuanzhu(BL 2)towards Yuyao(Ex-HN 4), Yingxiang(LI 20) towards Xiaguan(ST 7), Taiyang(Ex-HN 5)towards Xuanlu(GB 5), Dicang(ST 4) towards Jiache(ST 6), and Chengjiang(CV 24) towards Daying(ST 5), were used. Results: After 33 treatments, the warm-needling technique has an effective rate of 83.3%, while the electroacupuncture 67.7%. Conclusion: The therapeutic effect of warm-needling technique was better than that of electroacupuncture method.
6.Warm Needling Method on Rheumatoid Arthritis
Jinzhi LIU ; Yanli JV ; Minghai SHAO
Journal of Acupuncture and Tuina Science 2006;4(6):367-370
to observe the clinical effects of warm needling on rheumatoid arthritis.Methods:Patients with rheumatoid were treated with warming needling on the major acupoints of Guanyuan(CV 4),Qihai(CV 6),Zusanli(ST 36),Ganshu(BL 18),Shenshu(BL 23) and Pishu(BL 20),in combination with local acupoints and acupoints on the related meridians,meanwhile,other patients were treated with single needling as control. The patients' joint pain,tenderness,swelling,dysfunction index,gripping force,morning stiffness,walking time of 20 meters,rheumatoid factor,erythrocyte sedimentation rate,C response protein,IgG,IgA,and IgM were measured before and after treatments.Results:Warm needling could improve the rheumatoid arthritis patients' symptoms,and had an effective rate of 86.2%,while the single needling had an effective rate of 57.1%(P<0.01). And the therapeutic effects were related to the disease duration and condition. Conclusion:Warm needling has a better clinical effects on rheumatoid arthritis than the single needling,with obvious functions of anti-inflammation,relieving pain and regulating immunity.
7.Nosocomial Infection During Radiotherapy with Concomitant Weekly Paclitaxel for Advanced Nasopharyngeal Carcinoma: A Clinical Investigation
Weijun DING ; Jianhua WANG ; Haihua YANG ; Wei HU ; Minghai SHAO
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To investigate the risk factors of nosocomial infection in patients with advanced nasopharyngeal cancer during radiotherapy with concomitant weekly paclitaxel treatment. METHODS Twenty six cases of advanced nasopharyngeal cancer patients in our hospital were analyzed retrospectively. RESULTS There were 20 cases of nosocomial infection from inpatients.The infection rate was 76.9 % and isolates of bacteria were found,of which Candida albicans accounted for 46.2%,Gram-negatives were 38.5%,Gram-positives were 11.5%.The main risk factors were long time hospitalization,oral mucosal lesion,leukocytopenia,improper application of antibiotic and glucocorticoids. CONCLUSIONS To prevent and control nosocomial infection in advanced nasopharyngeal cancer during radiotherapy and concomitant chemotherapy,measures such as shortening hospitalization days,reinforcing oral nursing,preventing the leukocytopenia,reasonable using of antibiotics and glucocorticoids should be adopted.
8.Observation on the Efficacy of Acupuncture plus Tuina in Treating 102 Patients with Myofascitis
Hongwei CHEN ; Jieliang YAO ; Yongchun TANG ; Minghai SHAO
Journal of Acupuncture and Tuina Science 2006;4(5):305-306
Objective: To investigate the efficacy of horizontal acupuncture with sticking needles plus plucking manual technique in treating scapular, dorsal and lumbar myofascitis.Methods: One hundred and seventy-eight patients with scapular, dorsal and lumbar myofascitis were randomly allocated to observation group treated by horizontal needling with sticking needles plus plucking manual technique and control group treated by perpendicular acupuncture at the pain point. Results and conclusion: The cure rate, and the total effective rate in the observation group were 69.6%, and 100% respectively and those in the control group were 13.1%, and 82.5% respectively. Statistical analysis showed a very significant difference in curative effect between the two groups (P<0.01), indicating that the effect was significantly better in the observation group than in the control group.
9.Review of Leucopenia Treated by Acupuncture and Moxibustion from 1949 to 2004
Qinfeng HUANG ; Xuejun CUI ; Sheng LI ; Minghai SHAO
Journal of Acupuncture and Tuina Science 2006;4(3):129-131
To promote acupuncture practice, the general situation of acupuncture in treating leucopenia between 1949-2004 were analyzed on the basis of Chinese Modern Acupuncture Database. From 1981, references of acupuncture treating leucopenia increased annually and steadily.In clinic, hydroacupuncture, needling, and moxibustion are widely used, and the selected acupoints are those of Bladder Meridian of Foot Taiyang and Governor Vessel. Acupuncture-moxibustion have a good therapeutic effects on leucopenia.
10.Preliminary study of microsatellite instability and loss of heterozygosity in thymic squamous cell carcinoma
Minghai SHAO ; Wei HU ; Jianhua WANG ; Hongsheng LU ; Shilin CHEN
Chinese Journal of Thoracic and Cardiovascular Surgery 2010;26(1):45-48
Objective To investigate the frequency of micresatellite instability (MSI) and loss of heterozygosity (LOH) and select sensitive loci for studying microsatellite DNA imbalance in thymic squamous cell carcinoma. Methods 5 microsat-ellitc polymorphism markers and extrated DNA were selected from 9 specmiens of paired thymie squamous cell carcinoma/nor-real tissues. MSI and LOH in the specmiens of thymic carcinoma and relevant pericancerou tissues were detected by polymerase chain reaction (PCR) followed by 6% polyacrylamide gel electrophoresis(PAGE) with silver staining. Results MSI or LOH was detected in 9 thymic carcinoma tissues. The frequency of MSI or LOH was 66.7% (6/9) at loci of D6S1708, 33.3% (3/9) at TP53, 33.3% (3/9)at DM, 33.3% (3/9)at D11S988 and 0% (0/9)at D8S136, LOH at D6S1708 (5/6) was a common genetic alteration. DI1S988 had only LOH alteration. Conclusion D6S1708, TP53, DM, and D11S988 are sensi-tive loci for studying microsatellite DNA imbalance in thymic squamous cell carcinoma. Microsatellite DNA imbalance may play a certain role in occurrence and development of thymic squamous cell carcinoma, and the relationship between MSi or LOH.The linicopathological features of thymic squamous cell carcinoma needs further investigation.