Objective To explore the efficacy of group cognitive behavioral therapy for improving depressive symptoms and social functional in patients with major depressive disorder.Methods A total of 160 patients with major depressive disorder were randomly divided into intervention group (n=80) and control group (n=80).Intervention group was treated with conventional antidepressants combined with group cognitive behavioral therapy.Control group was treated with one conventional antidepressants.All participants were assessed with Hamilton Depression Scale (HAMD)and Scale of Social function of Psychosis Inpatients (SSFPI) before and 8 weeks after the treatment.Results After 8 weeks treatment,the scores of HAMD (14.76±9.48) was significantly reduced and the scores of SSFPI(30.09±4.34) were significantly increased in intervention group compared with the baseline ((37.91± 10.58),(12.40±2.56),all P＜0.01).The scores of HAMD were significantly lower and the scores of SSFPI were significantly higher in intervention group than that in control group((20.71±7.85),(22.63±3.63),all P＜0.01).Conclusion Group cognitive behavioral therapy is effective for major depressive disorder patients by reducing depressive symptom and improving social function.

ObjectiveTo investigate the experience and attitude of discrimination among family members of hospitalized patients with schizophrenia.Methods A total of 83 family members of hospitalized patients with schizophrenia were investigated using questionnaires of families experienced by discrimination and families' view on social discrimination of patients with mental illness.Results In the study,the three most common experiences included:68.7% of family members kept patients' schizophrenia as a secret in fear of discrimination;48.2% of family members failed in love or divorced because of discrimination;40.7% of family members were despised by neighbors. For the attitude of family members to discrimination,84.3% of family members thought that discrimination put too much stress on family members;79.5% of family members thought that social discrimination to patients with schizophrenia were more severe than to other disabled patients;71.0% of family members thought that social discrimination reduced their social activities;43.3% of family members thought that people discriminated patients with schizophrenia;and 77.1% of family members thought that in the past 20 years there was no reduction in the discrimination of patients with mental illness.Conclusions Discrimination commonly exists in schizophrenia patients' families and seriously affects family members both on psychological and social life. Doctors and nurses should assess the discrimination as part of the standard work not only for patients with mental illness but also for the family members,identify the high risk individual and help family members reduce the effects of discrimination on their lives.