1.Effects of laparoscopic cholecystectomy on immune and complement system
Chinese Journal of General Surgery 1994;0(05):-
In this study,changes in immunity were observed in 120 patients undergoing laparoscopiccholecystectomy. It was found that postoperative levels of IgG,IgM,CD3+,CD4+,and CD8+ were significantly higher than that of preoperative and postpneumoperitoneal with CO2 (P
2.Clinical study on laparoscopic appendectomy for acute appendicitis with previous abdominal surgery
Chaoliang LI ; Lan FANG ; Jianpeng HUANG ; Rongkun DONG ; Mingfu HAN
International Journal of Surgery 2013;40(7):447-450
Objective To evaluate the feasibility,safety and efficacy of laparoscopic appendectomy for acute appendicitis with previous abdominal surgery.Methods The clinical data of 253 patients with acute appendicitis undergoing laparoscopic surgery was retrospectively studied from Feb.2009 to Jun.2012,including 177 patients without previous abdominal surgery (no previous abdominal surgery group,NPAS group),76 patients with previous abdominal surgery (previous abdominal surgery group,PAS group).Parameters studied were conversion rates,operation time,blood loss,complications rate,length of hospital stay and the intestine function recovery time between two groups.Results The conversion rates were no significant difference between NPAS group and PAS group.The operation time of NPAS group and PAS group was (40.5 ± 12.3) minutes and (62.6 ± 14.2) minutes (P <0.05).The blood loss,intestine function recovery time,complications rate,and length of hospital stay were no significant minutes between NPAS group and PAS group after operation (P > 0.05).Conclusions Previous abdominal surgery prolongs the operation time of laparoscopic appendectomy,but history of abdominal surgery has no significant effect on laparoscopic surgical outcome,which may indicate that laparoscopic surgery for acute appendicitis with previous abdominal surgery is safe and effective and still has the adventages of less trauma,faster recovery.
3.Systematic Review of Clinical Efficacy and Safety of Macrolide Antimicrobial Drugs in the Adjuvant Treat-ment of Lung Infection of Pseudomonas aeruginosa
Fang HE ; Shixue HE ; Hejun CHEN ; Mingfu TUO
China Pharmacy 2015;(21):2956-2958,2959
OBJECTIVE:To systematically review the clinical efficacy and safety of macrolide antimicrobial drugs in the adju-vant treatment of lung infection of Pseudomonas aeruginosa (PA) and provide evidence-based reference for the clinical treatment. METHODS:Retrieved from PubMed,Ovid,CJFD,VIP,CBM and Wangfang database,randomized controlled trials(RCT)about sensitive antimicrobial drugs of PA combined with macrolide antimicrobial drugs (test group) vs. sensitive antimicrobial drugs of PA alone(control group)in the treatment of lung infection of PA were included and comprehensively evaluated using Jadad scale. The homogeneity results were analyzed by Rev Man 5.2 software. RESULTS:13 RCTs were included,involving 872 patients. Me-ta-analysis showed that the effective rate [OR=6.42,95%CI(4.23,9.74),P<0.001] and PA clearance rate[OR=6.10,95%CI(4.10, 9.09),P<0.001] in test group were significantly higher than control group;the time of body temperature returned to normal[MD=-1.14,95%CI(-1.35,-0.94),P<0.001],time of cough sputum disappearance [MD=-1.70,95%CI (-1.97,-1.44),P<0.001] and time of the blood returned to normal[MD=-1.24,95%CI(-2.04,-0.43),P<0.001] were significantly shorter than control group,there were significant difference between 2 groups. There was no significant difference in the incidence of adverse re-action [OR=1.30,95%CI(0.73,2.31),P=0.37]. CONCLUSIONS:Macrolide antimicrobial drugs have good efficacy and safety in the adjuvant treatment of PA infection. Duo to the limit of research methodology quality,it remains to be further verified by large-sample and high-quality RCT.
4.Treatment of partial inferior turbinate resection under nasal endoscopy on epistaxis in inferior nasal meatus.
Yizu TAO ; Pei CHEN ; Lianhe LIU ; Mingfu FANG ; Guang PENG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2008;22(17):783-784
OBJECTIVE:
To evaluate the effect of partial inferior turbinectomy in treating inferior nasal meatus epistaxis.
METHOD:
Twenty one case of inferior nasal meatus epistaxis were subjected to submucoperiosteous partial inferior turbinectomy and nasal cavity plugging under nasal endoscopy Its effect were analyzed.
RESULT:
All patients cured and discharged after 3-7 days. After 2 months to 3 years of follow up, no recurrence were seen.
CONCLUSION
Submucoperiosteous partial inferior turbinectomy under nasal endoscopy is an effective and reliable method in treating inferior nasal meatus epistaxis.
Adult
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Endoscopy
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Epistaxis
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surgery
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Humans
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Male
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Middle Aged
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Treatment Outcome
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Turbinates
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surgery