1.Comparison Between Neuromuscular Electrical Stimulation to Abdominal and Back Muscles on Postural Balance in Post-stroke Hemiplegic Patients.
Mingeun PARK ; Hyun SEOK ; Sang Hyun KIM ; Kyudong NOH ; Seung Yeol LEE
Annals of Rehabilitation Medicine 2018;42(5):652-659
OBJECTIVE: To compare the effects of neuromuscular electrical stimulation (NMES) to abdominal muscles and back muscles on postural balance in post-stroke hemiplegic patients. METHODS: Thirty post-stroke hemiplegic patients were prospectively enrolled and randomly assigned to one of the three groups: core muscle-strengthening exercise (CME) with NMES to abdominal muscles (group A), CME with NMES to back muscles (group B), and CME alone (group C). All subjects underwent their targeted interventions for 30 minutes each day, 5 days per week for 3 weeks under a conventional stroke rehabilitation program. Subjects were evaluated using Korean version of Berg Balance Scale (K-BBS), Trunk Impairment Scale (TIS), Korean version of Modified Barthel Index (K-MBI), Weight Distribution Index (WDI), and Stability Index (SI) just before and 3 weeks after intervention. RESULTS: Changes in K-BBS (p < 0.05) and TIS (p < 0.05) were significantly higher in group A (18.5±8.10, 6.6±1.90) and group B (19.9±5.44, 7.0±2.26) than in group C (8.4±4.14, 3.1±0.99). However, K-MBI, WDI, and SI failed to show any significant difference. No significant difference in all outcomes was observed between groups A and B. CONCLUSION: The effect of NMES to the abdominal muscles was similar to the effect on back muscles in terms of postural balance. This finding indicated that the NMES to the abdominal muscles may be an alternative for post-stroke hemiplegic patients contraindicated for NMES to the back muscles. Additional studies investigating the effects of NMES on abdominal and back muscles are needed.
Abdominal Muscles
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Back Muscles*
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Electric Stimulation*
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Humans
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Postural Balance*
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Prospective Studies
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Rehabilitation
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Stroke
2.Development and characterization of stable cell lines constitutively expressing the porcine reproductive and respiratory syndrome virus nucleocapsid protein.
Mingeun SAGONG ; Choi Kyu PARK ; Seong Hee KIM ; Sung Up MOON ; Seong Cheol CHO ; Changhee LEE
Journal of Veterinary Science 2010;11(2):169-171
Despite global efforts to control porcine reproductive and respiratory syndrome virus (PRRSV) infection, the virus continues to cause economic problems in the swine industry worldwide. In this study, we attempted to generate and characterize a panel of stable BHK cell lines that constitutively express the nucleocapsid (N) protein of type 1 or type 2 PRRSV. The established BHK cell lines were found to react well with N-specific antibodies as well as the hyperimmune serum of pigs raised against each genotype of PRRSV. Taken together, the data implicate a potential usefulness for the newly generated stable cell lines as a diagnostic reagent for PRRSV serology.
Animals
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Antibodies, Viral/analysis/immunology
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Blotting, Western/veterinary
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Cell Line
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Cricetinae
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Female
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Genotype
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Nucleocapsid Proteins/genetics/*immunology
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Porcine Reproductive and Respiratory Syndrome/diagnosis/*immunology
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Porcine respiratory and reproductive syndrome virus/genetics/*immunology
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Swine
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Transfection/veterinary