5. Optimal rotation time and pitch study of CT angiography for arterial occlusive diseases of lower limbs
Academic Journal of Second Military Medical University 2010;31(2):165-168
Objective: To identify the optimal rotation time and pitch of 64-slice spiral CT angiography for arterial occlusive diseases (AOD) of the lower limbs. Methods: We performed test-bolus in eighty patients with AOD of the lower limbs (48 with intermittent claudication and 32 with ischemic rest pain or ulceration) to confirm the aortic peak time, popliteal artery peak time and aortopopliteal bolus transit time. The patients were randomly assigned to receive two sets of scan protocols for lower limb arterial 64-slice spiral CT angiography (CTA) examination (n = 40), protocol A, with a gantry rotation time of 330 ms and a pitch of 1.0; protocol B, with a gantry rotation time of 500 ms and a pitch of 0. 85. Two experienced radiologists independently evaluated the image quality of the lower limb artery. Results: Great differences in the time to peak enhancement in the aorta (14-33 s) and popliteal arteries (20-48 s) and the aortopopliteal bolus transit time (4-24 s) were found between different AOD patients. Wide overlap of the time to peak enhancement and transit time was observed between intermittent claudication patients and ischemic rest pain or ulceration patients. The qualities of segment images were rated as excellent 63.3% (152/240), good 30.0% (72/240), and poor 30.0% (72/240) for protocol A, and excellent 98. 3% (234/238) and good 1. 7% (4/238) for protocol B, with no poor images in protocol B. Conclusion: 64-slice CTA with a gantry rotation time of 500 ms, a pitch of 0. 85, scan time>30 s, and with the contrast agent injection time maintained at 35 s, can obtain better image of lower limb arteries in patients with AOD of the lower limbs.
8.Progress on bone marrow mesenchymal stem cells transplantation for spinal cord injury.
Li WANG ; Qian WANG ; Xiao-Ming ZHANG
China Journal of Orthopaedics and Traumatology 2014;27(5):437-440
Bone marrow mesenchymal cells (BMSCs) are regarded as donor cells in cell transplantation therapies for spinal cord injury (SCI) for they have the ability of favourable proliferation and multi-directional differentiation, and are easily isolated and culturd and have less immunological reaction. It has been confirmed that subarachnoid space injection is the most ideal delivery technique of BMSCs. Bone marrow mesenchymal stem cells transplantation is safe and its reconditioning role is certain for SCI in early clinical application. The mechanism of BMSCs promoting functional recovery after SCI is probably concerned with vicarious function, nerve trophism, immunosuppression and promoting axonal regeneration by BMSCs.
Animals
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Bone Marrow Cells
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cytology
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Humans
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Mesenchymal Stem Cell Transplantation
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methods
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Mesenchymal Stromal Cells
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cytology
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Spinal Cord Injuries
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surgery
9.Eliciting thinking from the competition in basic medical design of experimentation for cultivating excellent doctors
Kangtao WANG ; Xuewen XIAO ; Ming LI
Chinese Journal of Medical Education Research 2016;15(1):32-34
The purpose of the National Competition in Basic Medicine Innovation Forum & Ex-perimental Design in colleges is to boost Excellent-doctor Education Training Plan, cultivating students' scientific research ability and other comprehensive capacity. In practice, the originality and the scientific nature of the selected topic were emphasized through the provision of scientific research funding. The teachers changed their traditional instructional concept and teaching models. They guided the students to select the scientific subjects and took various measures to change students ' learning mode, resulting in gradually pro-moting the students' scientific research level and comprehensive ability. The results showed that these novel strategies are feasible and effective, which may provide a new way for improvement of the excellent doctor program.
10.Percutaneous kyphoplasty for vertebral compression fractures in patients with osteoporosis
Dechang XIAO ; Weilin LI ; Ming PENG
Orthopedic Journal of China 2006;0(18):-
[Objective]To evaluate the efficacy of percutaneous kyphoplasty (PKP) in managing vertebral compression fractures due to osteoporosis(OVCF).[Method]Thirty-one OVCFs patients (46 vertebrae) undergoing PKP were retrospectively analyzed.In these patients,there were 9 males and 22 females who were from 61 to 78 years old with averaged 68 years,and the injured vertebrae were from T7 to L3.All the patients had plain X-rays and CT scan as well as MR images preoperatively.With all of the patients,local infiltration anesthesia were performed,20 were injected bilaterally while 11 unilaterally.Before and after operarion,the visual analogue scale (VAS) score was estimated and sagittal index(SI) as well as Cobb′s angle of the vertebrae were measured.The data were statistically analyzed with the method of paired t-test.[Result]The duration of follow up after operetion were 6 to 30 months with a mean of 18 months.The VAS score reduced from 8.7 before operation to 2.5 after operation (P