3.Anaphylactic shock in a boy after taking oral ofloxacin.
Yan-ming GU ; Xiao-yi CHEN ; Yong-qing WANG
Chinese Journal of Pediatrics 2005;43(8):607-607
Administration, Oral
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Anaphylaxis
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chemically induced
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physiopathology
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therapy
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Anti-Bacterial Agents
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administration & dosage
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adverse effects
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Blood Pressure
;
drug effects
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Child
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Diarrhea
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drug therapy
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Humans
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Male
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Ofloxacin
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administration & dosage
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adverse effects
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Treatment Outcome
5.Thoughts on learning objectives for speciality of clinical medicine in China
xiao-bo, LI ; gang, HUANG ; ming-min, GU
Journal of Shanghai Jiaotong University(Medical Science) 2008;0(S1):-
Objective To discuss some problems about current learning objectives for the speciality of clinical medicine in China,including the concepts,the decision-making systems and value-orientation,and to provide the reference for stipulating the learning objectives in future. Methods The objectives of some Chinese medical universities were collected from their websites.Some medical educators were consulted about their feelings about these learning objectives,and also were asked to identify their own objectives. Results Medical educators failed to distinguish their own objectives,and there were four main problems in current learning objectives: generalization,similarity and lack of individuality,difficulty in guide the curricula and teaching,and setting up too high object. Conclusion The learning objectives in clinical medicine should reflect both specialty characteristic and university individuality,so they should be drawn up by teachers,students and educatirnal administrators,moreover their value orientation should be eligible standard,not excellence.
6.Investigation and analysis on current situation of clinical teaching
ming-min, GU ; ming-de, ZHU ; ai-li, NUER ; xiao-bo, LI ; hui, XIA ; gang, HUANG
Journal of Shanghai Jiaotong University(Medical Science) 2008;0(S1):-
Objective To investigate the clinical teaching situation by using developmental inspection of School of Medicine,Shanghai Jiaotong University(SJTU-SM),and to put forward some suggestions. Methods By checking questionnaires and informal discussions,the relevant information was collected and analyzed by using SPSS statistics sofware. Results The clinical teaching quality of SJTU-SM was basically satisfied.The satisfaction from internship of grade 2004 was better than that of grade 2003.However,some problems in clinical teaching must be improved.Conclusion The investigation showed that the clinical teaching quality of SJTU-SM is being improving.However,in order to achieve the international accreditation standards,the quality guarantee system of clinical teaching need to be further perfected.
7.Establishment of prescription research technology system in Chinese medicine secondary exploitation based on "component structure" theory.
Xu-Dong CHENG ; Liang FENG ; Jun-Fei GU ; Ming-Hua ZHANG ; Xiao-Bin JIA
China Journal of Chinese Materia Medica 2014;39(21):4272-4276
Chinese medicine prescriptions are the wisdom outcomes of traditional Chinese medicine (TCM) clinical treatment determinations which based on differentiation of symptoms and signs. Chinese medicine prescriptions are also the basis of secondary exploitation of TCM. The study on prescription helps to understand the material basis of its efficacy, pharmacological mechanism, which is an important guarantee for the modernization of traditional Chinese medicine. Currently, there is not yet dissertation n the method and technology system of basic research on the prescription of Chinese medicine. This paper focuses on how to build an effective system of prescription research technology. Based on "component structure" theory, a technology system contained four-step method that "prescription analysis, the material basis screening, the material basis of analysis and optimization and verify" was proposed. The technology system analyzes the material basis of the three levels such as Chinese medicine pieces, constituents and the compounds which could respect the overall efficacy of Chinese medicine. Ideas of prescription optimization, remodeling are introduced into the system. The technology system is the combination of the existing research and associates with new techniques and methods, which used for explore the research thought suitable for material basis research and prescription remodeling. The system provides a reference for the secondary development of traditional Chinese medicine, and industrial upgrading.
Drug Prescriptions
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Medicine, Chinese Traditional
8.Observations on the Efficacy of Electroacupuncture at Huatuo Jiaji Points in Treating Motor Dysfunction in Stroke Patients During the Flaccid Paralysis Stage
Ting XIAO ; Fan HUANG ; Haitao YANG ; Ziji LU ; Ming TANG ; Zheng YUAN ; Zhuliang GU ; Tianlong CHEN
Shanghai Journal of Acupuncture and Moxibustion 2015;(3):194-196
[Ab]stract] Objective To investigate, according to core myodynamic theory, the clinical efficacy of electroacupuncture at Huatuo jiaji points in treating motor dysfunction in stroke patients during the flaccid paralysis stage.Methods Sixty stroke patients in the stage of flaccid paralysis were randomly allocated to treatment and control groups, 30 cases each. The control group received basic treatment and conventional acupuncture and the treatment group, electroacupuncture at Huatuo jiaji points in addition. The simplified Fugl-Meyer assessment (FMA) score and the Modified Barthel Index (MBI) score were counted before and after treatment and the clinical therapeutic effects were compared between the two groups.Results There were statistically significant pre-/post-treatment differences in the FMA score and the MBI score in the two groups (P<0.05). There were statistically significant post-treatment differences in the FMA score and the MBI score between the treatment and control groups (P<0.05). The total efficacy rate was 96.7% in the treatment group and 86.7% in the control group; there was a statistically significant difference between the two groups (P<0.05).Conclusion Electroacupuncture at Huatuo jiaji points has a promoting effect on the rehabilitation of limb function in the flaccid paralysis stage of stroke.
9.New exploration on effect of characteristics of traditional Chinese medicine components structure on multi-ingredient/component pharmacokinetics.
Jun-Fei GU ; Liang FENG ; Ming-Hua ZHANG ; Dong QIN ; Xiao-Bin JIA
China Journal of Chinese Materia Medica 2014;39(14):2782-2786
The study on the pharmacokinetics of traditional Chinese medicines (TCMs) is a linking science during the modernization of TCMs, and plays an important role in the studies on the complex material base of TCMs, the in vivo process of ingredient/ component and the pharmacokinetics-pharmacodynamics correlation. However, because of the multi-ingredient/component system of TCMs, how to scientifically reveal the pharmacokinetics that is consistent with TCMs' characteristics has long been a hotspot and difficulty for the exploration. The optimal composition structure of the material basis of TCMs shows the best efficacy, while the difference between the multi-ingredient/component composition structures in the efficacy is closely related to their absorption, transport, metabolism and excretion in vivo. In this article, the authors systematically review the study methods for pharmacokinetics of TCMs and their compounds, and explore the pharmacokinetics of TCMs based on the "component structure theory". As a result, the method for integrating TCM component structure and the TCM pharmacokinetics was proposed to be adopted to intensively study the effect of the component structure on the in vivo TCM multi-ingredient/component pharmacokinetic characteristics, in order to promote the TCM modernization and innovation in China.
Animals
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Area Under Curve
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Chemistry, Pharmaceutical
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Humans
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Medicine, Chinese Traditional
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methods
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Pharmacokinetics
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Structure-Activity Relationship
10.Multi-dimensional structure quality control over Salvia miltiorrhiza injection based on component structure theory.
Shao-Ying HU ; Liang FENG ; Ming-Hua ZHANG ; Jun-Fei GU ; Xiao-Bin JIA
China Journal of Chinese Materia Medica 2013;38(24):4375-4378
As the preparation process from Salvia miltiorrhiz herbs to S. miltiorrhiz injection involves complicated technology and has relatively more factors impacting quality safety, the overall quality control is required for its effectiveness and safety. On the basis of the component structure theory, and according to the material basis of S. miltiorrhiz injection, we discussed the multi-dimensional structure and process dynamic quality control technology system of the preparation, in order to achieve the quality control over the material basis with safety and effectiveness of S. miltiorrhiz injection, and provide new ideas and methods for production quality standardization of S. miltiorrhis injection.
Drug Compounding
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Drugs, Chinese Herbal
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administration & dosage
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adverse effects
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chemistry
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Injections
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Quality Control
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Safety
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Salvia miltiorrhiza
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chemistry