Anion Transport Proteins ; physiology ; Hair Cells, Auditory, Outer ; physiology ; Humans

Objective:To discuss the X-ray digital tomosynthesis (Digital Tomosynthesis, DTS) application value in the occult fractures of the scaphoid. Methods: we selected 19 patients in our hospital in 2012 examined by DTS, who were negative or highly suspicious of occult fracture with X-ray examination, and spiral CT (SCT) three-dimensional (3D) reconstructions were applied in seven patients. Results:There were 17 patients with fracture by DTS.7 patients showed fracture by spiral CT(SCT) three-dimensional(3D) reconstructions. Conclusion:Compared with X-ray examination, the image quality of Digital Tomosynthesis (DTS) is higher, which can show occult fracture better. Compared with CT, DTS can show spatial location of bony anatomy more clearly and can obtain more detailed information. With the important extension and supplement of CT and MRI, the distal tomosynthesisis is worth to be generalized for lower radiation, lower price, higher positive rate and high quality of the pictures.

Objective To investigate the effect of triptolide on asthmatic airway remodeling and signal transducer and activator of transcription 6 (STAT6), acid neutrophil chemokines (eotaxin) impact. Methods The total of 30 mice with ovalbumin (OVA) model of asthma were randomly divided into three groups, control group, asthma group and triptolide group. After 24 hours of the last shot, lung tissue was stained Bronchial inflammatory cell infiltration was determined by using semi-quantitative method and calculate the proportion of goblet cells in airway epithelial cells. Hydroxyproline was determined by McMillan airway mucus score. The mRNA level and protein level of STAT6 and eotaxin in airway epithelium were determined by RT-PCR and immunohistochemistry. Results Compared with asthma group, peribronchial inflammatory cells infiltration of triptolide group were reduced, which mucus index is (1.31 ± 0.23) and hydroxyproline is (284 ± 13) μmg/100 mg. it had a significant in asthma group (P < 0.05). Besides, the protein level and mRNA level of STAT6 and eotaxin were significantly decreased (P < 0.05). Moreover, it was a positive correlation between STAT6 and eotaxin level in airway epithelial (r = 0.668, P < 0.05). Conclusion Triptolide can inhibit airway remodeling and might through the down regulation of STAT6 and eotaxin expression.

Objective To observe the curative effects of Jawei-Wendan decoction in treating acute exacerbation of COPD due to phlegm blocking in lung. Methods From July 2010 to June 2013, 66 enrolled cases were randomly divided into a treatment group and a control group with 33 in each. Aside from receiving anti-infection and symptomatic treatment as the control group did, the treatment group was also given orally Jawei-Wendan decoction. The symptoms, pulmonary function and the variety of the laboratory indexing were observed before and after the treatment. Results ①The treatment group attained better curative effects(P<0.05) and got shorter symptomatic relief time of cough, expectoration and breathless(The T-value is respectively 16.770, 8.635, 16.762, P<0.05). ②After 7-days treatment, the cure rate of the treatment group was 63.64%, and the control group was 39.39%. Their difference was conspicuous(P<0.05). The total effective rate in treatment group was 96.97%, which was 90.91% in control group. Their difference was inconspicuous(P>0.05).③The pulmonary function indices increased significantly in the treatment group[The values of FEV1、FVC and FEV1/FVC% are (1.41±0.46)L, (2.18±0.63)L and (66.41±6.33)% before treatment, which were (2.21± 0.55)L, (2.83±0.53)L and (77.37±7.64)%after treatment, P<0.01]. A comparison of the two groups showed significant differences regarding the pulmonary function indices(P<0.05). Conclusion Jawei-Wendan decoction had good curative effect in treating acute exacerbation of COPD due to phlegm blocking in lung.

Objective To investigate the expression of c-erbB-2 in breast cancer and its relationship with prognosis.Methods The expression of c-erbB-2 in breast cancer was detected by immunohistochemistry assays in 60 cases of breast cancer.Results The positive expression level of c-erbB-2 in invasive breast cancer was signifi-cantly higher than that in other kinds of breast cancer(P<0.01).The positive expression level of c-erbB-2 in the metastatic breast cancer with four lymph nodes was higher than in the early cancer with no lymph node involvement (P<0.01).The 10 years survival rate in negative expression of c-erbB-2 was higher than in positive expression(P<0.05).Conclusion c-erbB-2 is important for physicians to instruct the treatment of the breast cancer and judge the prognosis.

Objective To investigate the expression of c-erbB-2 in breast cancer and its relationship with prognosis.Methods The expression of c-erbB-2 in breast cancer was detected by immunohistochemistry assays in 60 cases of breast cancer.Results The positive expression level of c-erbB-2 in invasive breast cancer was signifi-cantly higher than that in other kinds of breast cancer(P<0.01).The positive expression level of c-erbB-2 in the metastatic breast cancer with four lymph nodes was higher than in the early cancer with no lymph node involvement (P<0.01).The 10 years survival rate in negative expression of c-erbB-2 was higher than in positive expression(P<0.05).Conclusion c-erbB-2 is important for physicians to instruct the treatment of the breast cancer and judge the prognosis.

Aged ; Female ; Foreign Bodies ; pathology ; Humans ; Laryngeal Diseases ; Larynx ; pathology ; Vestibule, Labyrinth

Bone Cysts ; diagnosis ; Bone Cysts, Aneurysmal ; diagnosis ; Humans ; Male ; Middle Aged ; Sphenoid Bone ; pathology

Objective To evaluate the efficiency and safety of Percusurge guardwire distal protection system in coronary intervention in patients with acute myocardial infarction. Methods Three male patients with acute myocardial infarction were enrolled in the study. Primary angioplasty was performed for 2 of them, 2 and 7 hours after onset of the infarction symptom, respectively. Selective angioplasty was performed 17 days after infarction for the third case. Percusurge guardwire system was used during the procedure. Results Procedure success was achieved for all of the 3 cases. Lot of thrombus was sucked out. The infarct-related arteries had TIMI 3 flow at the end of the procedures. The patients′ symptoms were resolved soon after the procedure. Minor dissection was seen in one case which did not obstruct the distal flow and was left alone. Conclusion Percusurge guardwire system can be used safely and effectively in coronary intervention in the thrombus-laden arteries such as acute myocardial infarction.

Objective To summarize the effect and safety of percutaneous coronary intervention (PCI) for CHD in patients with single patent coronary artery. Methods We collected the data of CHD in 10 patients with single patent coronary artery who underwent PCI and analyzed them retrospectively. Results All patients with single patent coronary artery had successful PCI. Symptoms of all the CHD patients had been significantly relieved after PCI. No major adverse cadiac events occurred in hospitalization. Conclusion The data suggest that the patients with single patent coronary artery might be treated with PCI effectively and safely.