1.The Evaluation of Pain Palliation Efficacy of ~(153)Sm-EDTMP Treating Bone Metastasis of Lung, Breast and Prostate Cancers
Ming ZHAO ; Jing YU ; Ming LIU
Journal of Chinese Physician 2001;0(08):-
Objective To investigate the clinical effect of 153 Sm-EDTMP treatment on pain palliation in the patients with bone metastasis of lung cancer, breast cancer or prostate cancer. Methods 166 patients with bone metastasis of cancers were intravenously injected 18.5~37 MBq/kg (0.5~1.0 mCi/kg ) body weight of 153 Sm-EDTMP, once a month or two months. Results The effective rate of pain palliation of 153 Sm-EDTMP treating bone metastasis of lung cancer, preast cancer and prostate cancer were 68.5%, 89.3% and 100%, respectively. The efficacious rate of pain palliation in breast and prostate cancers was significantly higher than that in lung cancer (P
2.Research progress on detecting low molecular weight analytes based on surface plasmon resonance sensing technology
International Journal of Biomedical Engineering 2010;33(1):1-6
Surface plasmon resonance (SPR) sensing technology is a high-tech optical detection technolo-gy developed quickly in recent years, which combines biology, polymer chemistry and sensing technologies to form a rapid, sensitive, specific, portable and easy to operate detection technology. This paper outlines the mech-anism of SPR sensing technology for detection of low molecular weight analytes, the main application methods and research progress, discusses the advantages and shortages of the method, and foretastes the development prospect of this technology.
3.CAP and ISO15189 accreditation requirements of verification and validation tests for clinical molecular diagnostic assays
Chinese Journal of Laboratory Medicine 2013;(2):105-108
College of American Pathologists (CAP) and International Standard Organization (ISO)15189 accreditation provides requirements to the verification and validation tests for clinical molecular diagnostic assays.The article will introduce the requirements in these aspects including the differences between the two accreditation systems,the differences between the verification and validation tests,the essential factors and standardized framework of the verification and validation tests for clinical molecular diagnostic assays.
4.Cyanoacrylate-nano drug:A bone-targeted therapy
Chinese Journal of Tissue Engineering Research 2013;(25):4692-4698
10.3969/j.issn.2095-4344.2013.25.018
5.Comparison of the efficacy of skin rehabilitation therapies between comprehensive treatment and simple Chinese medicine steam spray after deep facial burn
Chinese Journal of Medical Aesthetics and Cosmetology 2013;(3):187-189
Objective To study the efficacy of simple Chinese medicine steam spray and comprehensive rehabilitation nursing after facial burn deep Ⅱ degree.Methods 80 patients were randomized into the treatment group (40 cases) and the control group (40 cases).The treatment group was given the treatment of Chinese medicine steam spray.The control group was given the treatment of Chinese medicine steam spray,pressure therapy,physical therapy,rehabilitation training and psychotherapy.The clinical efficacy of two groups was evaluated respectively after 3 months.Results After 3 months,the skins of most of patients in the treatment group were nearly normal with no pigmentation and scar hyperplasia.The cure rate was 72.5 %,the obvious effective rate was 12.5 %,and the effective rate was 7.5 %.Some patients in the control group were lightly and inconspicuously pigmented,but the pigmentation area was reduced.The colour of their skins was not different from that of the normal skin.The cure rate was 42.5 %,the obvious effective rate was 12.5 %,and the effective rate was 25.0 %.The effects of the two groups were significant differences (P<0.05).Conclusions Comprehensive rehabilitation nursing after the facial burn can reduce the pigmentation and scar hyperplasia and improve the quality of life.
6.The application of DPK LCD module to medical instrument
Chinese Medical Equipment Journal 2004;0(09):-
This paper stated the design of DPK colour LCD module and its application for the medical instrument. The hardware interface between MCS-51 and DPK LCD module is presented and the software driver base on KeilC51 language is introduced in this paper. The LCD module is well used in the "Cerebral oximeter for the newborn".
8.Application of Spiral CT for Pancreatic Adenocarcinoma: Emphasis on the Value of the Tumor-pancreas Contrast
Chinese Journal of Medical Imaging Technology 2001;17(2):108-110
Objective To evaluation the application value of two-phase enhanced spiral CT in pancreatic adenocarcinoma. Methods Two-phase enhanced spiral CT was performed in 27 cases of pancreatic adenocarcinoma. After plain CT examination, performed arterial phase(25s after infusion)and portal venous phase(60~70s after infusion)with a 150ml bolus injection of contrast material at 3ml/s. CT attenuation values of tumor and normal pancreas in all scanning phase were obtained and the tumor-pancreas contrast was calculated. Results Mean tumor enhancement were 48±8 HU(arterial phase)and 72±6 HU(portal venous phase), normal pancreas enhancement were 125±18 HU、98±11 HU, mean tumor-pancreas contrast was significantly differenced on arterial phase (73±21 HU)and portal venous phase (25±12 HU). Conclusion Excellent tumor-pancreas contrast is obtained with arterial phase scans, as such it is of significance reference value for diagnosis pancreatic adenocarcinoma.
9.Discussion on ways of improving the ability of doctor-patient communication of paediatric sur-geon in standardized training
Chinese Journal of Medical Education Research 2015;(3):322-324
The doctor-patient relationship is always the focus in the society. The relationship seems more complex and sensitive in the pediatric surgical ward because its patients are kids. However, the pediatric surgical residents' ability of doctor-patient communication is lack of systemic and norma-tive training, which is not good for the mutual understanding between doctors and patients. This study explores how to enhance the residents' doctor-patient communication skills from the perspective of awareness, professional knowledge and some specific skills. In the meantime, it discusses the need to train the teachers and set up a regular examination-assessment system.
10.Timed morphological changes of human hepatocytes L-02 cultured at high density by the support of spherical porous chitosan microcarriers
Chinese Journal of Tissue Engineering Research 2015;(12):1924-1930
Abstract BACKGROUND: Recently, microcarrier culture as a high concentration cel culture technology has been used in hepatocyte culturein vitro. OBJECTIVE:To periodicaly observe the morphological changes of human hepatocyte L-02 cultured by the spherical porous chitosan microcarrier. METHODS:The self-made spherical porous chitosan microcarrier sample as a support to culture human hepatocytes L-02 acted as experimental group; non-spherical porous chitosan microcarrier as a support to culture human hepatocytes L-02 as control group. Cels in two groups underwent cel count at regular time, and the morphological changes were observed in the experimental group, including inverted phase contrast biological microscope observation and scanning electron microscope observation. RESULTS AND CONCLUSION:The quantity of cultured cels in the two groups was increased in the first 3 days and reached the peak at the 3rd day. The cel quantity in the experiment group was obviously higher than that in the control group (P < 0.05). There was no significant difference in the three samples of the experimental group (P > 0.05). The quantity of hepatocytes adhered to the microcarrier surface was gradualy increased in the former 3 days under the inverted phase contrast biological microscope. There were lots of cel clusters on the surface of a greater part of microcarriers, with the total survival rate of more than 90%, and hepatocytes kept a good morphological structure. Under the scanning electron microscope, lots of hepatocytes adhered tightly to each other on the surface and section of microcarrier as wel as inside the microcarrier. It is indicated that the self-made spherical porous chitosan microcarrier as a support in three-dimensional environment can undergo cel culture with high concentration.