ObjectiveTo compare the effect of psychological treatment only and psychological combined with fluoxetine treatment in reducing symptom of depression, anxiety and in improving of cognitive and daily living abilities for post-stroke depression patients.MethodsAll patients with post-stroke enrolled in hospital between 1996 and 2001 and were evaluated by using of the Self-rating Depression Scale (SDS), the Self-rating Anxiety Scale (SAS), Scale of Elderly Cognitive Function (SECF), and Ability of Daily Living (ADL). SDS score was equal or greater than 50 points (SDS≥50) selected as subjects for this study. A total of 115 patients were randomized divided into psychological with fluoxetine treatment group (Group A,54 patients) and psychological treatment group (Group B,61 patients). There is no significant difference between two groups in age, education, and left or right side of hemiplegics. Statistical analysis was performed by using Chi test and t test to compare the 2 groups at day 0 (baseline) and after 2 months.ResultsThe level of depression and anxiety reduced significantly in both Group A and Group B from baseline to end of treatment (P<0.001). Both groups had significant improvement in daily living ability (P<0.001).There was no significant improvement in cognitive ability (P>0.5). There was no significant differences on SDS, SAS, SECF, and ADL scores from baseline to end of treatment (P>0.5).Conclusions There were similar effect of psychological with fluoxetine treatment and of psychological treatment only on post-stroke depression.

ObjectiveTo analyze the relationship among depression and anxiety and other possible factors in post-stroke patients.Methods510 hospitalized stroke patients from 1997 to 2004 were evaluated with the Scale of Elderly Cognitive Function (SECF), Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), and Activities of Daily Living (ADL) in 7 days after admission and re-examined after two months.ResultsThe depression group exhibited the longer course of disease, a high ratio of hemiplegia in left side, lower ADL scores and higher SAS scores at time of admission. There were significant differences between depression and non-depression group. However, there was no significant difference between the depression and cognitive function. There were also significant differences between anxiety group and non-anxiety group. Patients with anxiety displayed symptoms of low ADL scores and higher SDS scores at time of admission, and ADL scores increased after treatment. Additionally, the course of disease was longer and reduction of anxiety level was lower. The levels of depression and anxiety significantly reduced in depression group and anxiety group when compared to the control group.ConclusionEarly rehabilitation can help to reduce depression level. Modest anxiety may help stroke patients to improve their ADL. There is close relationship between depression and anxiety.

As an evolutionary process, the robotic technology has been recently applied in the minimally invasive surgery. The robotic surgical system can provide cardiac surgeons with less invasive manner and dexterity manipulation in coronary artery bypass graft. The robotic minimally invasive coronary artery bypass graft usually includes robotic internal thoracic artery harvesting, robotic assistant coronary artery bypass graft and totally robotic coronary artery bypass graft.

Objective To establish and assess a model of abdominal postoperative fatigue syndrome (POFS) in rats. Methods After 70% hepatectomy was performed, the following observations of the animals were made:general condition, rat tail suspension test,weight carrying swim fatigue test,serum levels of albumin,ferrition,and iron,pathologic assessment of injury of small intestinal mucosa and hepatic albumin gene expression .Results After 70% hepatectomy of the rats,their general candition was poor,the level of physical tolerance decreased,they showed a certain amount of depression,and marked changes were found in nutritional index,stress injury of small intestinal mucosa and hepatic albumin gene expression.Conclusions A 70% hepatectomy rat model has the basic characteristics of clinical abdominal POFS, and can be used as an experimental animal model for the study of abdominal POFS.

Folicacid, an essential microelement to human, is closely related to tumor development and progression. Recent studies have suggested that alow folate intake and impaired folate metabolism may be involved in the carcinogenesis of pancreaticcancer, but the specific mechanism remains unclear. In this paper we review the progress in the association of folate deficiency with pancreatic cancer from an epidemiological perspective, and introduce the progress in the mechanism by which folated efficiency causes tumor.

Objective: To evaluate the relationship between folate intake and risk of pancreatic cancer. Methods: We searched various databases, including Cochrane Cental Register of Clinical Trials, Pubmed, EMBASE, CBMdisc, and CNKI for relevant reports; manual search was also done to retrieve reports from the references of identified ones. According to the predefined inclusion and exclusion criteria, prospective and case-control studies on the relationship of folate intake with risk of pancreatic cancer were included. After evaluating the quality of studies, we performed meta-analysis by Stata version 11 software. Results: A total of 6 cohort studies and 3 casa-control studies, which involving 2, 209 patients, were included in the present analysis. The results of meta-analysis showed that people with highest dietary folate intake was associated with a 28% reduced risk of pancreatic cancer compared with those with the lowest dietary folate intake, and this descending trend of risk was more obvious in the cohort studies with relative risk (RR) as the effect size (pooled RR=0.51 [95%CI, 0.29-0. 89], P= 0.017); meanwhile, the pooled odds ratio(OR) in the casa-control studies was 0.79 (95%CI [0.66-0.94], P=0.008). People with the highest total folate intake (dietary and supplement folate) was associated with a 33% reduced risk of pancreatic cancer compared with those with the lowest one, with the pooled OR in the casa-control studies being 0.53 (95%CI [0.30-0.96], P= 0.036). Conclusion: The findings in this study indicate that increase of total folate (dietary and supplement folate) and dietary folate intake may be a protective factor for pancreatic cancer.

The rapid development of artificial intelligence technology has achieved a breakthrough in many disciplines. Artificial intelligence has a far-reaching significance in promoting the further development of laboratory medicine. At present, artificial intelligence technology has gradually penetrated into all processes of laboratory work, such as laboratory data processing, laboratory data mining and laboratory quality control. It not only improves efficiency, but also provides important information for clinical diagnosis and treatment supporting information. The functions of laboratory physicians are likely to undergo corresponding transition and adjustment in the future. Therefore, it is a general trend to promote the development and leap of the next generation of laboratory medicine by artificial intelligence, and the future of laboratory medicine will usher in the "artificial intelligence era".

Objective Probing into the rationale of DRGs payment standards for references to making DRGs payment standards.Methods Based on the DRGs grouping results of circulatory diseases cases admitted by a tertiary hospital from 2003 to 2005,two typical combinations were selected to determine the payment standard for each DRGs combination.Unnecessary medical expenses were excluded.Results According to the percentage of unnecessary medical expenses,Angina,non-special nursing,and class 1 nursing were in a group,with unnecessary medical expenses per ease of 758.00 yuan;CAG,single stent implantation,acute myocardial infaction as the main diagnose were in a group,with medical expenses per case of 2814.03 yuan;such expenses account for 6.20% of the total hospitalization expenses of both groups.Conclusions If the average expenses with unnecessary medical expenses excluded are set as the combined payment standard,hospitals will be restrained from unnecessary medical behaviors and expenses so incurred.

The minimally invasive approach is the direction of cardiac surgery.With the development of telemanipulation and computer technology,the minimally robotic surgery has become reality.As the one of the most minimally invasive cardiac surgery,the robotic surgical system provides cardiac surgeons with less invasive manner and dexterity manipulation.Robotic cardiac surgery is an evolutionary process and has resulted in a substantial increased attention to surgeons and patients.This review is to introduce the recent clinical application of robotic technology in cardiac surgery.