The multifunction surgical needle threading device is a new kind of surgical device which can thread a surgical needle rapidly and efficiently.This device has the functions Of threading,thread catting and thread storing.It is small in volu- me.easy to operate and be disinfected and convenient to carry.Particularly, it can be used in darkness,which is very important and practical in field hospi tals.The results of clinical test ferformed in 8 hospitals including Bethune Inte- rnational peace Hospital showed that this device operated satisfactorily and was worth expanding.

Objective To investigate the distribution characteristics and drug resistance of pathogenic bacteria in ICU . Methods The bacteria identification and drug sensitive test were carried out on all pathogenic bacteria in ICU of our hospital from January 2013 to December 2013 .Results A total of 187 strains of pathogenic bacteria were separated ,among them 37 strains (19 .79% ) were Gram‐positive bacteria ,which was dominated by staphylococcus aureus ,with drug resistance rate to vancomycin , teicoplanin and linezolid of 0 .00% ;135 strains were Gram‐negative bacteria (72 .19% ) ,which was dominated by pseudomonas aeruginosa ,acinetobacter baumannii ,klebsiella pneumoniae and escherichia coli ,the drug resistant rate of acinetobacter baumannii to cefoperazone/sulbactam and minocycline was lower (43 .59% ,46 .15% ,which of pseudomonas aeruginosa to amikacin ,cefotaxime , cefoperazone/sulbactam were 27 .91% ,32 .56% and 30 .23% ,respectively ;15 strains(8 .02% ) of fungi were isolated ,which were mainly candida albicans and candida tropicalis .Conclusion Regular detection of distribution types and drug resistance change can provide the basis for climical rational use of antibacterial drugs .

Based on a concept of the hyperfocal distance from photographic lens,this study proposes that emmetropia presents far-hyperfocal distance,near-hyperfocal distance and accommodative hyperfocal distance.When emmetropic presbyopias completely lose the ability of accommodation,its farthest blur point is not beyond 1.5 m,even not being at infinity,and the phenomenon of dark focus both completely match with the definition of hyperfocal distance.On the other hand,after cycloplegic mydriatics in emmetropia,it could be found in the region of depth-of-field that there is no change in the back depth of field (clearness in far vision),but change was found in the front depth of field (blur in near vision).It conforms well to the definition of the hyperfocal distance,demonstrating that human eyes belong to the hyperfocal distance optical system.Furthermore,it is reported that the emmetropic presbyopias rarely matched the spectacles higher than +2.50 D in their whole life;therefore,it can be inferred that their accommodative amplitude in youth is equal to this corrected value.This value accounts for about 4％ of the total refractive power in human eyes,so it is suggested that human eye is a micro zoom optical system.Based on the objective existence of hyperfocal distance,the author proposes that human eye is an integrated accommodative mechanism.It includes three components:the accommodative mechanism of near vision,the measuring and controlling mechanism of near vision,and the general control of near vision.This paper discusses the accommodative mechanism of near vision and the resting mechanism of distance vision based on the hyperfocal distance,and considers that when human eye transfer into the accommodation of near vision from the normal distance vision of hyperfocal distance.There are three different pushing forces contributing to lens deformation and its anterior shift,and these forces cause four different accommodative efforts,which constitute the real accommodative efforts in the relative tissue.This paper also points out that it is only the mode of pushing accommodation that can make the lens vary refraction quickly and greatly,and control the amount of deformation effectively.That can not be achieved by the stretching mode proposed by Tscherning & Schachar,because some authors have verified that excessive pulling would result in decline in the refraction,which would be difficult to regulate and control the eye.Similarly,the self-bulging mode of Helmholtz & Gullstrand will not work neither,because it is unable to control the amount of lens deformation that is its fatal defect.

30 mmHg on day 1 after SLT.Blurring and anterior uveitis were controlled. Conclusion SLT may be a safe and effective therapy for POAG.

Objective To investigate the specific expression of nucleolin in the development of cap-stage tooth germ of mouse embryo,and detect the possible biological function of nucleolin. Methods In situ hybridization and immunohistochemistry were performed to detect the expression of nucleolin mRNA and protein in the development of tooth germ at embryo day 15(E15).Double staining for apoptotic cells and nucleolin was employed to explore the relationship between nucleoin and apoptosis in tooth germ. Results The expression of nucleolin mRNA and protein was mainly detected in the cervical loop,inner epithelium and the underlying dental papilla.Moreover,nucleolin protein was also located in the primary enamel knot and basement membrane.It was revealed by double staining that the fluorescence images of nucleolin and the location of apoptotic cells were not overlapped. Conclusion The expression pattern of nucleolin mRNA do not completely coincide with that of nucleolin protein at the cap stage of tooth germ.The location for nucleolin protein in the basement membrane suggests that nucleolin may be involved in the reciprocal interactions between the inner epithelium and dental papilla mesenchyme,subsequently affect the morphogenesis of tooth germ.

Objective: To synchronously inhale Chinese materia medica compound using particle as inhalation drug delivery system, notoginseng total saponins-tanshinone composite particle was prepared. Methods: The composite particle of notoginseng total saponins-tanshinone was prepared by solvent deposition method and was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), differential thermal analysis (DTA), particle size analysis, and high-performance liquid chromatography (HPLC). Results: The notoginseng total saponins-tanshinone composite particle was successfully prepared by solvent deposition method, the results of characterization proved that tanshinone was coated on the notoginseng total saponins core particle. Conclusion: The preparation of composite particle provides an effective way for synchronous inhalation of Chinese materia medica compound prescription and technical support for the preparation of compound dry powder inhalations.

Cardiomyopathy, Restrictive ; diagnosis ; surgery ; Diagnosis, Differential ; Humans ; Infant ; Male

Objective To evaluate the curative effect of conjoined tendon transfer for coracoclavicular ligament reconstruction in the treatment of Rockwood grades Ⅲ-Ⅳ acromioclavicular joint dislocation,c Methods A retrospective case control study was performed for 64 cases of acromioclavicular joint dislocation admitted from October 2007 to August 2014.There were 53 males and 11 females,with age of (43.8 ± 10.5) years (range,23 to 65 years).Rockwood grade Ⅲ was seen in 27 cases and grade-Ⅳ in 37.According to the treatments,26 cases underwent proximally based conjoined tendon transfer for coracoclavicular ligament reconstruction combined with clavicular hook plate (ligament reconstruction group) and 38 cases only treated with clavicular hook plate (internal fixation group).Visual analogue scale (VAS),Constant shoulder score and postoperative complications were compared between the two groups before and after operation.Results All patients were available for a mean follow-up of 3.7 months (range,2 to 4 months).VAS was (7.58 ± 1.03) points in ligament reconstruction group and (7.15 ± 1.03)points in internal fixation group before surgery (P ＞0.05),and was (2.38±0.94)points in ligament reconstruction group and (2.08 ± 0.99) points in internal fixation group 3 months after operation (P ＞ 0.05).Constant shoulder score was (86.46 ± 6.59) points in ligament reconstruction group and (87.68 ± 6.59) points in internal fixation group after operation (P ＞ 0.05).Six cases (16％) had recurrent joint dislocation in internal fixation group,while none of the patients in ligament reconstruction group had recurrence (P ＜ 0.05).Conclusion Improved procedure of proximally based conjoined tendon transfer for coracoclavicular ligament reconstruction can effectively reduce the recurrence rate of acromioclavicular joint dislocation.

Abstract?AlM: To assess the efficacy and safety of trypan blue and indocyanine green ( lCG ) for continuous curvilineal capsulorrhexis ( CCC ) in mature or hypermature phacoemulsification.?METHODS: A total of 122 eyes of 122 cases with cataracts in mature and hypermature were randomly divided into three groups, trypan blue staining group was 46 eyes of 46 cases as group A, lCG staining group was 40 eyes of 40 cases as group B, control group was 36 eyes of 36 cases as group C. Staining groups were used to 0. 2mL trypan blue or lCG injected into the anterior chamber during operation, respectively. The success rate of CCC, lens posterior capsule rupture and implanted intraocular lens pouch were observed and compared during operation. Anterior chamber inflammation was observed after operation, and compared with the control group to observe and analysis.? RESULTS: The success rate of CCC, implanted intraocular lens pouch were statistically significant difference in trypan blue staining group ( group A ) than that in control group (group C) (P<0. 05). lmplanted intraocular lens pouch was statistically significant difference in lCG group ( group B ) than that in control group ( group C ) ( P<0. 05 ) . The rate of lens posterior capsule rupture was no statistically significant difference in all three groups ( P > 0. 05 ) . Anterior chamber inflammation was no significant difference in the postoperative reaction among the three groups.?CONCLUSlON:The application of trypan blue or lCG for lens capsule staining before CCC in lack of red reflective mature and hypermature cataracts is safe and effective, both results are comparable. lt guarantees a complete CCC and improves the success rate of phacoemulsification.

OBJECTIVE:To observe therapeutic efficacy and safety of tegafur,gimeracil and oteracil potassium combined with oxaliplatin assisting with radiofrequency ablation(RFA)in the treatment of liver metastases after radical operation of rectal cancer. METHODS:A total of 130 patients with liver metastases after radical operation of rectal cancer were randomly divided into control group and observation group,with 65 cases in each group. After RFA one week,control group was given Oxaliplatin injection 130 mg/m2 intravenously,d1,more than 3 h. Observation group was additionally given Tegafur capsule,for consecutive 14 d,drug with-drawal of 7 d,as a treatment course. A treatment course lasted for 3 weeks,and both groups received 2 courses of treatment. Short-term efficacies of 2 groups were observed as well as complete ablation rate,local recurrence rate,survival rate and the occur-rence of toxic reaction. RESULTS:The total remission rate,disease control rate,complete ablation rate,1-year,2-year and 3-year survival rates of observation group were significantly higher than those of control group,and local recurrence rate was significantly lower than control group,with statistical significance(P<0.05). There was no statistical significance in the incidence of toxic reac-tion between 2 groups(P>0.05). CONCLUSIONS:Tegafur,gimeracil and oteracil potas siucn combined with oxaliplatin assisting with RFA shows significant therapeutic efficacy for liver metastase after radical operation of rectal cancer,and can significantly de-lay disease progression,reduce local recurrence rate and prolong survival time,and does not increase the occurrence of toxic reac-tion.