1.Clinical Observation on Termination of Pregnancy Effects of 75 Patients Applied with Guizhi Fuling Capsule Combined with Mifepristone
International Journal of Traditional Chinese Medicine 2008;30(5):365-366
Objective To observe the effects of termination of pregnancy with Guizlfi Fuling Capsule plus Mifepristone.Methods 75 early pregnant women were randomly recruited into a treatment group and a control group.Women in the control group were applied with Mifepristone plus Misoprostoi.Form the 3rd day,women in the treatmcnt group were applied wilh Guizhi Fuling Capsule(3 times daily,and 3 granules for each time)for successive 7 days oil the basis of medicines used in the control group.Compared and analyzed the therapeutic effects of both groups.Results The average time for ovum evacuation in the control group and the tretment group was(6±1.8)h and(3±2.6)h separately.Besides both bleeding volume and bleeding time in the Izeatment group were lower than the eonlxol group.Conelusion Guizhi Fuling Capsule plus Mifeoristolle therapy will shorten ovum evacuation time and decrease bleeding volume.
2.Application of Medial Collateral Ligament Release Technique in Knee Arthroscopic Surgery for Medial Tibiofemoral Compartment Tightness
Chinese Journal of Minimally Invasive Surgery 2016;16(2):177-180
Because of the factors such as degeneration or congenital dysplasia which leads to medial tibiofemoral compartment tightness, the arthroscopic surgery of this part might have limited vision and narrow operating space, which causes missed diagnosis and iatrogenic injury.Medial collateral ligament ( MCL) release technique is a simple, effective and safe procedure.By releasing part of the ligament fiber, this operation can effectively expand the visual field and operation space.avoiding the risk of iatrogenic injury of cartilage and missed diagnosis.MCL release technique is an effective method to solve the arthroscopic examination and endoscopic operation for medial compartment tightness of the knee joint.This article reviewed the technique of MCL release.
5.Effects of angiotensin Ⅱ on matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) mRNA expressions in rat mesangial cells
Ming LUO ; Helin DING ; Zuzhi FU
Chinese Journal of Diabetes 2006;14(5):383-384
The study of glomerular mesangial cells of normal rats showed that angiotensin Ⅱ (ATⅡ) down-regulated the expression of MMP-2 mRNA, did not have significant effect on TIMP-2 mRNA. And in consequence, ATⅡ down-regulated the ratio of MMP-2 mRNA to TIMP-2 mRNA.
6.Influence of intraoperative posture intervention on drainage in patients after gynecological laparoscopic surgery
Yun CHEN ; Ming ZHANG ; Yan DING
Chinese Journal of Nursing 2010;45(4):314-316
Objective To investigate the influence of intraoperative posture intervention on drainage in patients after gynecological laparoscopic surgery. Methods A total of 1250 patients who were scheduled for gynecological laparoscopic surgery including laparoscopic-assisted salpingoplasty,oophorocystectomy,ectopic pregnancy,vaginal hysterectomy,myomectomy and appendectomy were randomly divided into two groups. The patients' posture was changed from Trendelenburg position to level lithotomic position during suction by the circulating nurses in the experimental group,while after surgery in the control group. The volume and time of drainage,and the length of stay after surgery were compared between the two groups. Results The volume and time of drainage,as well as the length of stay after surgery had significant differences between the two groups (P<0.05). Conclusions Intraoperative posture intervention is helpful for the treatment effect of drainage after gynecological laparoscopic surgery.
7.Acute non-isovolemlc hemodilution during operation In the elderly patients
Ming DING ; Hao JIANG ; Ting WANG
Chinese Journal of Anesthesiology 1994;0(05):-
35 % and the intraoperative blood loss was expected to be 800-1 600 ml. The operations were performed under combined general-epidural anesthesia. General anesthesia was induced with fentanyl 2-4 ?g?kg-1 , thiopentone 5 mg?kg-1 and succinylcholine 1.5mg? kg-1 and maintained with isoflurane inhalation and intermittent iv boluses of vecuronium. Epidural anesthesia was performed at T5-6 (thoracic surgery), T10-11 (upper abdominal surgery) or L3-4 (lower abdominal surgery) . A mixture of 0.1% lidocaine +0.2% dicaine was used for epidural block during operation. The patients were randomly divided into 2 groups: (1) ANIH group ( n = 18) and (2) AHH group ( n = 20) . Blood volume (BV) was calculated according to following formula: BV (ml) (male) = Height (cm)? 28.5 + Body weight (kg) ? 31.6 - 2 820,BV(ml) (female) = Height(cm)? 16.25 + Body weight (kg) ? 38.46 - 1 369. 1 000-1 200 ml of 6% HES (200/0.5) and 500 ml of lactated Ringer's solution (about 25%-30% of BV) were infused at a rate of 50ml?min-1 when induction of anesthesia was started in both groups. In group I (ANIH) 400-600 ml of blood (about 10%-15% of BV) was removed through radial artery before induction of anesthesia. The removed blood was reinfused at the end of surgery. Vital signs (BP,HR,CVP and ST-T changes) , Hct, oncotic pressure and arterial blood lactate concentration were monitored during operation. Results The vital signs were fairly stable during perioperative period in both groups. Transient hypotension developed in 16.7% (3/8 in group Ⅰ ) and 15.0% (3/20 in group Ⅱ ) of patients during induction of anesthesia. CVP was significantly elevated in both groups but the increase in CVP was significantly higher in group Ⅱthan that in group Ⅰ . In group Ⅰ (AN1H) moderate hemodilution was achieved (Hct = 29.9% 2.9%) while in group Ⅱ (AHH) only mild hemodilution was achieved (Hct = 32.9% ?2.9%) .Hct was significantly higher in group Ⅰ(31.5% ?5.1%) than that in group Ⅱ (27.7% ?3.6%) at the end of surgery. Blood loss was comparable between the two groups, and oncotic pressure and blood lactate level were within normal range in both groups. Conclusion ANIH is more effective and safer than AHH without obvious adverse effects, and can avoid exceedingly high CVP commonly seen in AHH. ANIH is a hemodilution technique of choice in the elderly patients.
8.Research on Reconstruction of Ultrasound Diffraction Tomography Based on Compressed Sensing.
Shaoyan HUA ; Mingyue DING ; Ming YUCHI
Journal of Biomedical Engineering 2015;32(5):975-982
Ultrasound diffraction tomography (UDT) possesses the characteristics of high resolution, sensitive to dense tissue, and has high application value in clinics. To suppress the artifact and improve the quality of reconstructed image, classical interpolation method needs to be improved by increasing the number of projections and channels, which will increase the scanning time and the complexity of the imaging system. In this study, we tried to accurately reconstruct the object from limited projection based on compressed sensing. Firstly, we illuminated the object from random angles with limited number of projections. Then we obtained spatial frequency samples through Fourier diffraction theory. Secondly, we formulated the inverse problem of UDT by exploring the sparsity of the object. Thirdly, we solved the inverse problem by conjugate gradient method to reconstruct the object. We accurately reconstructed the object using the proposed method. Not only can the proposed method save scanning time to reduce the distortion by respiratory movement, but also can reduce cost and complexity of the system. Compared to the interpolation method, our method can reduce the reconstruction error and improve the structural similarity.
Algorithms
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Artifacts
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Image Processing, Computer-Assisted
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Tomography
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Ultrasonics
9.The Acting Mechanisms of Statins and Their Application in the Prevention and Treatment of Stroke
Ding-Ming SUN ; Zhi-Jun ZHANG ;
International Journal of Cerebrovascular Diseases 2006;0(10):-
Stroke is one of the most important causes of disability throughout the world.Epide- miological and clinical studies have demonstrated that statins significantly decrease the incidence of ischemic stroke.In addition to lipid-lowering effect,statins may also have a number of other acting mechanisms that are not dependent on reducing cholesterol levels.Moreover,statins inhibit cerebral vasospasm caused by subarachnoid hemorrhage.For most of the individuals,the safety and tolerability of statins are well.
10.STUDY ON APOPTOSIS IN ACUTE ISCHEMIC AND REPERFUSED RAT MYOCARDIUM
Ming XU ; Qingyun ZENG ; Chengying DING ;
Acta Anatomica Sinica 1954;0(02):-
Objective To demonstrate in vivo that there is different degree myocardium apoptosis during acute ischemia and reperfusion and to explore prelimarily the relations between myocardium apoptosis and the expression of Bcl 2/Bax protein in rats. Methods The morphologic features of apoptotic cardiocytes were pursuited by transmission electron microscopy.DNA extracted from cardiocytes were used to identify the apoptotic DNA ladder by agarose gel eletrophoresis. DNA fragmentation was identified histochemically by TUNEL staining. Expression of Bcl 2/Bax protein in apoptotic myocardium was observed by means of immunohistochemistry and analysed by image analysis system. Results In both ischemia and reperfusion groups morphologic features of apoptotic myocardium were observed by transmission electron microscopic and the apoptotic cardiocytes were detected by the TdT mediated dUTP nick end labeling (TUNEL) staining. However, the apoptotic DNA ladder was observed only in the 2 hour reperfusion group. The reperfusion group showed a decrease in OD value of the Bcl 2 protein( P