A computer-based online search was conducted in PUMMED, English Medical Current Contents (EMCC), China Journal Full-text Database (CJFD), and Wanfang Database to summarize application and research progress of large-diameter femoral head hip prosthesis from January 1995 to January 2008. There were 62 literatures in total. Previous studies reported that when diameter of femoral head hip prosthesis was>32mm, joint worn out remarkably. During recent years, more and more basic and clinical researches demonstrate that diameter of femoral head is not correlated with wear rate; in particular, diameter of femoral head is not related to wear rate of artificial joint made by high cross linked polyethylene, metal, and ceramics. The superiority of large-diameter femoral head hip prosthesis has been paid more attention because of stability and activity. With the enlargement of diameter of femoral head, dislocated incidence decreases remarkably, and improvement of head-neck ratio increases the activity of prosthesis and reduces collision between two prostheses. Recently, large-diameter femoral head hip prosthesis has been widely applied for metal-on-mental hip joint, in particular, for hip resurfacing arthroplasty; in addition, large-diameter femoral head hip prosthesis plays a distinct role in joint replacement.

Acute Kidney Injury ; chemically induced ; Aristolochia ; adverse effects ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; adverse effects ; therapeutic use ; Humans ; Male ; Middle Aged ; Nephrotic Syndrome ; drug therapy ; Phytotherapy

Flipped classrooms have been developed in recent years at home and abroad although there is no systematic application in Chinese higher education institutions. College of Stomatology Shanghai Jiao Tong University has discussed the application prospect of flipped classrooms in medical education and methods of increasing effect and quality by informational means and classroom reform through a case de-sign and application in stomatology, in which performance comparison of the students in flipped classroom and traditional classroom is done as well as recognition of the students to flipped classrooms by a question-naire survey. Still, procedure, experience, supporting conditions and tips on the design and application have been concluded. The practice in classrooms tells us the students accept flipped classrooms positively and scientific design and application may increase teaching result as an effect method. Education management department of higher education institutions and faculty may take advantage of that method with varying degrees.

Objective To study the effect of different therapies for posterior lumbar disc herniation.Methods A total of 8 000 patients with lumbar disc posterior surgery were enrolled in this research at our hospital.The technical points of the patients in different times were analysed.The results of the operation were observed.Results From January 1980 to December 1990,patients underwent laminectomy.From January 1991 to December 2000,patients were treated with laminectomy and semi-lamina.From January 2001 to December 2016,the open window accounted for 86.0％,expanding the window or semi-lamina accounted for 11.0％,and the whole laminar plate only accounted for 3.0％.After 2000,the accuracy of the diagnosis was 98.0％,the excellent rate of operation was 99.8％,the average operation time was(80±15)min,and the blood loss was(100±20)mL.Among them,the rate of I/A healing was 99.8％,dural tear rate was 4.0％,nerve root injury rate was 0.5％,and cerebrospinal fluid leakage rate was 0.9％.The incidence of complications in the cases after 2000 was significantly lower.Conclusion By summarizing the operation technique of posterior lumbar disc herniation,the operation error can be avoided and the incidence of complications of surgical injury can be reduced.

The activities of low density lipoprotein (LDL) receptors in 15 organs and tissues from 5 human fetuses of the ages of 22 to 34 weeks were determined using a membrane filter assay of the specific binding of ~(125)I-LDL to tissue homogenates. The results showed that the adrenal cortex (465 ng/mg protein) had the highest activity of ~(125)I LDL specific binding seven times than that of the medulla. Adipose tissue (214 ng/mg protein) and liver (102 ng/mg protein) ranked second. Relatively high bindings were also observed in the skeletal muscle (89 ng/mg protein), brain (65 ng/mg protein), kidney (60 ng/mg protein) and spinal cord (56ng/mg protein). It was found that the activity of LDL receptors in the central nervous system of human fetus was higher than that of cows, of human adultsand of humam fetuses of 16 to 20 weeks as reported by other investigators. Relatively high level of LDL receptor mRNA in human fetal brain was also found by ~(32)P-cDNA probe hybridization analysis. It is suggested that the growing and developing central nervous system of human fetus reqiresmore cholesterol. In addition, We also observed preliminarily that the tendency of LDL receptors activities in liver and adrenal gland cortex were gradually inereased with fetal age.

China ; Disasters ; Earthquakes ; Emergency Medical Services ; Humans ; Public Health

0.05).Conclusion DTI can noninvasive detect the potential disorder of corpus eallosum in vivo,thus providing useful information to differentiate the cerebral ischemia disease from multiple sclerosis.

BACKGROUND: Lower urinary tract abnormality (LUTA) can lead to end-stage renal disease (ESRD). However, insufficient attention has been paid to these patients in China, and they are usually thought unsuitable for kidney transplantation because of high incidences of graft dysfunction and septic complication.OBJECTIVE: To explore the characteristics and postoperative follow-up after kidney transplantation in four patients with LUTA.DESIGN, TIME AND SETTING: A retrospective analysis of LUTA cases was performed from July 2002 to June 2006 at the Organ Transplantation Center of Chinese PLA, Second Affiliated Hospital of General Hospital of Chinese PLA.PARTICIPANTS: Four ESRD cases of LUTA, who received allograft kidney transplantation.METHODS: Four cases of LUTA experienced detail evaluation before kidney transplantation. Ureter was reimplanted into the original bladder during transplantation and suprapubic cystostomy was performed as urinary drainage.MAIN OUTCOME MEASURES: Patient and graft survival, graft function, urinary tract infection (UTI) and graft rejection were supervised after surgery and quality of life was evaluated.RESULTS: Two patients recovered well with normal renal function and no rejection. Despite the moderate but easily controlled UTI, they handled the urinary diversion well and were satisfied with the quality of life. One patient experienced an acute rejection 17 days after transplantation and survived with functional graft until now after the rejection was reversed. One patient lost the graft for repeated hemorrhage at the site of vascular anastomosis, and then returned to hematodialysis.CONCLUSION: Kidney transplantation is suitable but special for patients with LUTA. Careful evaluation before transplantation, suitable urinary drainage and rigorous follow-up after surgery are keys to the success of kidney transplantation for this subgroup of patients.

Anastomosis, Surgical ; methods ; Humans ; Organ Transplantation ; adverse effects ; methods ; Postoperative Complications ; etiology ; surgery ; Vascular Surgical Procedures ; methods

Objective To study the clinicalpathological characteristics,surgical treatment andprognosis of the gastrointestinal stromal tumor(GIST).Methods The clinical data of 160 cases of pathologically confirmed GIST were retrospectively reviewed.Clinical features,pathological characteristics andimmune markers were studied by multiple factor analysis.Results There were no intraoperative or deathsin 140 patients who underwent radical resection.Univariate analysis of survival revealed significant differences in the main tumor pathological characteristics,including mitotic figure and metastasis and Fletcher'sclassification(P <0.05).Immunohistochemical results showed that the positive rates of KIA and CD133were 97.6% and 81.3% respectively,and their influences to survival prognosis were of statistical significance(P <0.05).A total of 145(90.6%)patients finished the follow up and 53 cases of them had multiple liver metastasis.These patients received imatinib mesylate(400 mg/d)and the efficacy was significant(P <0.05).Multivariate regression analysis showed that Fletcher's classification and imatinib mesylatewere the independent risk factors affecting prognosis.Conclusion Fletcher's classification is an effectivemethod for evaluating the prognosis of GIST.Radical resection and imatinib mesylate can reach a remarkable curative effect in treating original and metastatic lesions of the GIST patients.