1.Analysis of Causes of Postoperative Acute Kidney Injury in Patients with Gastrointestinal Surgery
Danqing BI ; Zhu ZHOU ; Danyan BI ; Huayou LUO ; Ming ZHONG
Journal of Kunming Medical University 2013;(11):84-86
Objective To analyze the risk factors of acute kidney injury (AKI) in the patients undergoing gastrointestinal surgical procedures.Methods We retrospectively analyzed all gastrointestinal surgical patients nearly 2 years who were in the first affiliated hospital of Kunming Medical University and the first people's hospital of Yunnan province.Results The incidence of AKI was 2.1%.Univariate analysis and multivariate analysis indicated that: age>65 years, emergency operation and serious infection were significantly related with the incidence of AKI.Conclusion AKI is a common complication after gastrointestinal surgical procedures.This study showed that age>65 years, emergency operation, serious infection were risk factors most likely associated with postoperative AKI development.
5.The Prevention and Therapy of Postoperative Acute Kidney Injury after Gastrointestinal Surgery
Danqin BI ; Danyan BI ; Ming WENG ; Cheng TANG ; Qiuhong FU ; Mingfen HU ; Ming ZHOUN
Journal of Kunming Medical University 2014;(2):112-114
Objective To explore the prevention and treatment of acute kidney injury (AKI) after gastrointestinal surgical procedures.Method We retrospectively analyzed the data of patients underwent gastrointestinal surgery in recent 2 years in the First Affiliated Hospital of Kunming Medical University and the First People's Hospital of Yunnan Province. Result The incidence of AK1 was 2.1%. Elderly patients with basic diseases had poorer prognosis than non-elderly patients. Conclusion In the patients after gastrointestinal Surgery, early rehydration, diuresis, ant-infection and preventive hemodialysis can achieve the goal of prevention and treatment of acute kidney injury in early stage.
7.Injury of hepatic mitochondria and its mechanism in rats with endotoxemia.
Ming-Hua BI ; Shu-Wen ZHANG ; Ban-En WANG
Chinese Journal of Applied Physiology 2004;20(1):90-97
Animals
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Endotoxemia
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metabolism
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pathology
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Female
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Liver
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metabolism
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pathology
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Male
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Mitochondria, Liver
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metabolism
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Rats
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Reactive Oxygen Species
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metabolism
8.Investigation and Analysis of Short Drugs in 5 Third-grade Class-A Hospitals in Anhui Province
Ming BI ; Feihu CHEN ; Xuefeng XIE ; Jing JU
China Pharmacy 2015;26(33):4620-4622
OBJECTIVE:To provide empirical reference for protecting the supply of clinical drugs. METHODS:Literature re-view was combined with the conditions of drugs that lost the bidding in the centralized bidding in Anhui province to determine the short drugs need to investigate. Questionnaire was adopted to investigate the situations and reasons of short drugs in 5 third-grade class-A hospitals of 5 areas in Anhui province from Nov. 2013 to Oct. 2014. RESULTS:A total of 5 questionnaires were sent out, and 5 were received with effective response rate of 100%. There were totally 54 short drugs in the 5 third-grade class-A hospitals, including the most serious shortage of drugs for neurocirculatory system,accounting for 20.37%. Shortage was mainly due to the low price of drugs,accounting for 48.15%,and insufficient supply,less suffering patients/low dosage and other reasons. CON-CLUSIONS:In view of the shortage of drugs,government departments should improve the drug pricing and bidding policy,pro-duction enterprises should enhance the enterprise production and development capabilities,business companies should optimize the distribution pattern of network and medical institutions should establish drug management system with a clear division of power and responsibility to relieve the drug shortages.
9.Effect of Active Components of Zhi Ga ncao Decoction and Their Combinatio n on Triggered Activity and Myocar-dial Damage in Isolated Ischemia -reperfusion Rat Heart
Xinggao LI ; Qi CHEN ; Mengyu HUANG ; Ming BI ; Lanyin CHEN
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(01):-
Objective To observe the effect of active components(glycyrrhizic acid monoaminate,total ginsenoside and to-tal ophiopogonoside)of Zhi Gancao Decoction(ZGD)and their combination on the triggered activity and myocardial dam-age in the isolated ischemia -reperfusion rat heart.Methods Isolated rat heart was treated with L angendroff perfusion and monophase action potential technology was applied.Results &Conclusion Total extract of ZGD,single active c omponents and their combination can markedly l ower the incidence of cardiac triggered activity,prevent the myocardiu m from injury and decrease the incidence of arrhythmia induced by ischemia -reperfusion in rats and the effects of their com bination are positively related to the doses.
10.Clinical Features of Cerebral Infarction with or without Diabetes Mellitus
Ming ZHANG ; Jinsheng ZHANG ; Jiajing BI ; Zhengzheng HAN ; Yongxi HUANG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(9):861-862
Objective To investigate the clinical features of cerebral infarction complicated with diabetes mellitus (DCI) compared withthose without diabetes mellitus (NCI). Methods 80 DCI and 86 NCI hospitalized patients were reviewed with their serumal glucose, lipid,uric acid, hemorheology and carotid ultrasound. Results The total cholesterol, low density lipoprotein and uric acid were significantly higherin DCI group than in NCI group (P<0.05), while high density lipoprotein was significantly lower (P<0.05). There were significant differencesbetween these two groups in Hemorheological indicators except hematokrit (P<0.01). The carotid intima media thickness (IMT) wassignificantly higher in the DCI group than in the NCI group (P<0.05). Conclusion DCI patients suffered in more serious lipid, uric acid,hemorheological disorder, and IMT compared with NCI.