1.Combination of contrast-enhanced cardiac MR and nuclear myocardial imaging in evaluation of myocardial viability in ischemic cardiomyopathy
Yan LI ; Minjie LU ; Li WANG ; Zuoxiang HE ; Shihua ZHAO ; Minfu YANG
Chinese Journal of Radiology 2015;(6):425-429
Objective To explore the imaging characteristics and the complementarity of contrast?enhanced cardiac magnetic resonance CMR and nuclear myocardial perfusion/metabolic imaging in the evaluation of myocardial viability in patients with ischemic cardiomyopathy. Methods A total of 111 patients with diagnosed coronary artery disease and left ventricular dysfunction were retrospectively enrolled in this study. All patients underwent CMR and nuclear myocardial imaging within 1 month. Cine CMR was employed to evaluate cardiac function and wall motion. Contrast?enhanced CMR and myocardial perfusion/metabolic images were quantitatively assessed using a standard 17-segment and 5-score system. Dysfunctional segments were classified as viable or non?viable based on contrast?enhanced CMR and myocardial perfusion/metabolic imaging, respectively. No enhancement or sub?endocardial enhancement was defined as viable, while transmural enhancement was defined as non?viable. Severely matched perfusion/metabolism defects on nuclear imaging were assigned as non?viable while other patterns were considered as viable. Kappa index was calculated to evaluate the diagnostic concordance in assessing myocardial viability between contrast?enhanced CMR and myocardial perfusion/metabolic imaging. Results Among 1 887 segments in 111 patients, 80.3%(1 516/1 887) were dysfunctional. Of them, 63.3%(959/1 516) were viable and 36.7%(557/1 516) were non?viable on contrast?enhanced CMR, while 79.7%(1 208/1 516) were viable and 20.3%(308/1 516) were non?viable on nuclear myocardial imaging. The two modalities had a moderate concordance (Kappa=0.46,P<0.01). In segments with normal perfusion and metabolism, 73.9% (431/583) had various extent of enhancement but most of them(84.2%, 363/431) were subendocardial. On the other hand, 21.0%(117/557) segments with transmural enhancement had hibernating myocardium on nuclear imaging. Conclusions Contrast?enhanced CMR and nuclear myocardial imaging have a moderate concordance in the evaluation of myocardial viability in ischemic cardiomyopathy. Combination of the two modalities is expected to improve the diagnostic accuracy in assessing myocardial viability.
2.The Levels of Plasma Insulin and Erythrocyte Insulin Receptors in Children with Acanthosis Nigricans Associated with Obesity
Hong ZHU ; Liping ZHANG ; Haitao ZHOU ; Yi WU ; Chundi HE ; Minfu ZHANG
Chinese Journal of Dermatology 2003;0(11):-
Objective To investigate the role of insulin resistance in the pathogenesis of childhood benign acanthosis nigricans with obesity and the relationship between insulin resistance and insulin receptors.Methods Fasting plasma insulin and the amount of erythrocyte insulin receptors were determined among17children with benign acanthosis nigricans with obesity(CBANO),with16cases of simple adiposis and15healthy children as controls.Results The levels of plasma insulin were higher in CBANO than those in sim-ple adiposis and healthy controls;however,the amount of erythrocyte insulin receptors was lower in CBANO than that in simple adiposis and healthy controls.Conclusion Insulin resistance caused by diminished in-sulin receptors may play an important role in pathogenesis of CBANO.
3.The Associations of Family Functioning, General Well-Being,and Exercise with Mental Health among End-Stage RenalDisease Patients
Qi WANG ; Hongjian LIU ; Zheng REN ; Wenjing XIONG ; Minfu HE ; Nan LI ; Xinwen FAN ; Xia GUO ; Xiangrong LI ; Hong SHI ; Shuang ZHA ; Xiumin ZHANG
Psychiatry Investigation 2020;17(4):356-365
Objective:
This study aims to explore the relationships of family functioning, general well-being, and exercise with psychological distress.Furthermore, we investigated the special roles of general well-being and exercise on the association between family functioningand psychological distress.
Methods:
Of 769 end-stage renal disease (ESRD) patients participated in the cross-sectional study which consisted of the 12-item GeneralHealth Questionnaire (GHQ-12), the Family APGAR Scales, and the General Well-Being Schedule. The collected data were analyzedusing multiple linear regression analysis and path analysis.
Results:
The prevalence of psychological distress was 72.3%. Family functioning, general well-being and exercise were associated factorsof psychological distress (p<0.05). The indirect effect of family functioning on psychological distress was partially mediated by generalwell-being (Effect=-0.08, 95% CI=-0.11, -0.04). In addition, the effect of family functioning on general well-being was moderated byexercise (Index=-0.092, SE=0.033, 95% CI=-0.159, -0.029).
Conclusion
The prevalence of psychological distress among ESRD patients was high. Family functioning, general well-being and exercisewere associated with psychological distress. Family functioning could affect psychological distress partially by affecting general wellbeing.Furthermore, exercise had a significant moderating effect on the relationship between family functioning and general well-being.Psychiatry Investig 2020;17(4):356-365
4.Establishment and associated factors of health records among young Chinese migrants.
Hong SHI ; Xiumin ZHANG ; Xiangrong LI ; Zheng REN ; Hanfang ZHAO ; Minfu HE ; Xinwen FAN ; Xia GUO ; Shuang ZHA ; Shuyin QIAO ; Yuyu LI ; Yajiao PU ; Hongjian LIU
Environmental Health and Preventive Medicine 2021;26(1):39-39
BACKGROUND:
Most Chinese migrants have been faced with obstacles to getting access to local public health services. Young migrants among internal migrants make a major contribution to the economy. However, the establishment of their health records has been ignored. This research was aimed at exploring the status and associated factors of the establishment of health records among young Chinese migrants.
METHODS:
Data were obtained from the 2017 China Migrants Dynamic Survey (CMDS). Chi-square test and binary logistic regression were performed to investigate the associated factors of the establishment of health records among young Chinese migrants.
RESULTS:
Approximately 30.2% of young migrants had their health records established in inflow communities. Urban residence, medical insurance (insured), and lower average monthly household income were attributed to the establishment of more health records. Young migrants who were in northeast China and across provinces and immigrated for working or engaging in trade were less likely to have health records established. Young migrants who participated in social activities and public affairs activities and took type of people in touch as natives in the inflow area showed a higher possibility of establishing health records. Meanwhile, receiving health education and hearing about national basic public health services (BPHSs) were beneficial for establishing the health records of more young migrants.
CONCLUSION
This study showed that the health records of young migrants had a relatively low establishment rate. Sociodemographic and migration characteristics, health status, public health services, and social integration factors were all related to the health record establishment of young Chinese migrants.
Adolescent
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Adult
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China
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Female
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Health Records, Personal
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Humans
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Male
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Transients and Migrants/statistics & numerical data*
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Young Adult
5.Associations of negative life events and coping styles with sleep quality among Chinese adolescents: a cross-sectional study.
Zheng REN ; Xiumin ZHANG ; Yue SHEN ; Xiangrong LI ; Minfu HE ; Hong SHI ; Hanfang ZHAO ; Shuang ZHA ; Shuyin QIAO ; Yuyu LI ; Yajiao PU ; Xinwen FAN ; Xia GUO ; Hongjian LIU
Environmental Health and Preventive Medicine 2021;26(1):85-85
BACKGROUND:
Limited published research has examined the relationships of negative life events and coping styles with sleep quality in Chinese junior high school students. We aimed to investigate the prevalence of poor sleep quality and to clarify the role of coping styles between negative life events and sleep quality.
METHODS:
A cross-sectional study of 3081 students was conducted in Ganzhou City, Jiangxi Province, Southeastern China. Adolescent Self-Rating Life Events Checklist, Simplified Coping Style Questionnaire, and Pittsburg Sleep Quality Index were applied to assess negative life events, coping styles, and sleep quality, respectively. Descriptive analyses, independent-samples t tests, one-way analyses of variance, Pearson correlation analyses, and structural equation modeling (SEM) were applied to analyze the data.
RESULTS:
The prevalence of poor sleep quality was 26.7%. Negative life events (B = 0.038, P < 0.001) and negative coping style (B = 0.049, P < 0.001) demonstrated a positive association with poor sleep quality, while positive coping style indicated a negative association with poor sleep quality (B = -0.029, P < 0.001). Interactions of negative life events and coping styles with sleep quality were not found (all P > 0.05). The association between negative life events and sleep quality was mediated by negative coping styles.
CONCLUSIONS
Our results indicated that poor sleep quality was common in these Chinese adolescents. Negative life events and negative coping style were associated with an increased prevalence of poor sleep quality, while the positive coping style was related to a decreased prevalence of poor sleep quality. A negative coping style mediated the association between negative life events and sleep quality.
Adaptation, Psychological
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Adolescent
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Child
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China
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Cross-Sectional Studies
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Humans
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Life Change Events
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Psychology, Adolescent
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Psychology, Child
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Sleep