1.Quality Management of Hematology Tests in Blood Center.
Korean Journal of Blood Transfusion 2017;28(1):13-27
The primary goal in transfusion medicine is to promote high standards of quality in all aspects of transfusion, including production, management, and transfusion of blood components. To achieve this goal, a transfusion service quality management system should be established. Such a system should include several organizational structures, responsibilities, policies, processes, procedures, and resources with provided specifications and regulations. In this review, we summarize the current knowledge and practices regarding the quality management of hematology tests applied to the donor selection and production of blood components, including red blood cells, platelets, fresh frozen plasma, and cryoprecipitates in the field at blood centers.
Donor Selection
;
Erythrocytes
;
Hematology*
;
Humans
;
Plasma
;
Social Control, Formal
;
Tissue Donors
;
Transfusion Medicine
2.Unusually Elevated Serum Insulin Level in a Diabetic Patient during Recombinant Insulin Therapy.
Serim KIM ; Yeo Min YUN ; Mina HUR ; Hee Won MOON
Laboratory Medicine Online 2013;3(1):56-59
Herein, we report a case of unusually elevated serum insulin level as a result of increased anti-insulin antibody (IA)-bound insulin after continuous subcutaneous insulin infusion therapy. Detecting free insulin (unbound IAs) levels after polyethylene glycol pre-treatment could be useful to assess functional insulin levels in diabetic patients receiving insulin therapy. The E170 insulin assay can estimate total insulin (bound IAs and free insulin) levels, but it does not measure the levels of exogenous insulin analogues.
Humans
;
Insulin
;
Insulin Antibodies
;
Polyethylene Glycols
4.Neutrophil Gelatinase-Associated Lipocalin as a Promising Novel Biomarker for Early Detection of Kidney Injury.
Annals of Laboratory Medicine 2018;38(5):393-394
No abstract available.
Kidney*
;
Lipocalins*
;
Neutrophils*
5.Advances in Automated Urinalysis Systems, Flow Cytometry and Digitized Microscopy.
Annals of Laboratory Medicine 2019;39(1):1-2
No abstract available.
Flow Cytometry*
;
Microscopy*
;
Urinalysis*
6.Phenotypic consensus markers for plasma cell myeloma.
Korean Journal of Hematology 2012;47(4):239-240
No abstract available.
Consensus
;
Multiple Myeloma
;
Plasma
;
Plasma Cells
10.Performance Evaluation of MassTrak LC/MS/MS Tacrolimus Kit.
Jaekwang NOH ; Heewon MOON ; Mina HUR ; Yeomin YUN
Journal of Laboratory Medicine and Quality Assurance 2009;31(1):199-205
BACKGROUND: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) are used increasingly for tacrolimus monitoring. However, there are still variability of results due to home-brew reagents, so which cannot be warrantable data. We evaluated the analytical performance and clinical usefulness of a newly introduced MassTrak LC/MS/MS Tacrolimus kit (Waters Corporation, USA). METHODS: The performance of LC-MS/MS for determination of tacrolimus concentration were analyzed using patient samples and MassTrak LC/MS/MS Tacrolimus kit including calibrators, quality controls, internal standard, column and neat solution with respect to linearity, precision, lower limit of detection, lower limit of quantitation, sample carryover and comparison according to CLSI guidelines. The LC-MS/MS using home-brew reagents were performed for comparison test. RESULTS: The LC-MS/MS using MassTrak LC/MS/MS Tacrolimus kit showed a good linearity (R2> or =0.997) and precision (CV< 8%). Assigned LLOD (0.4 ng/mL) and LLOQ (0.8 ng/mL) were validated and carryover was estimated 0.5%. The system correlated well with the LC-MS/MS using home-brew reagents (R> or =0.974). CONCLUSIONS: LC-MS/MS using MassTrak LC/MS/MS Tacrolimus kit for determination of tacrolimus concentration showed good performance for linearity, precision, LLOD, LLOQ, carryover and comparison. Introduction of MassTrak LC/MS/MS Tacrolimus kit could be warranted results by manufacturer and useful for management of quality control.
Humans
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Indicators and Reagents
;
Limit of Detection
;
Mass Spectrometry
;
Quality Control
;
Tacrolimus