1.The therapeutic mechanism of Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent
Chinese Journal of Primary Medicine and Pharmacy 2011;18(22):3049-3050
Objective To investigate the therapeutic effect of traditional Chinese medicine,Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent and its mechanism.Methods Patients in control group( n =54) received regularly therapy and treatment group( n =55) was treated with regularly therapy and Songling Xuemaikang Capsule for eight weeks respectively.The clinical therapeutic effeets,Barthel index,hemorheology indexes,serum lipid and C-reactive protein (CRP) were determined.Results The total clinical effective rate in treatment group and control group was 70.9% and 55.6% (P < 0.01 ).After eight weeks treatment,the scores of Barthel Index,hemorheology indexes,the amounts of serum lipid and CRP in treatment group were improved significantly as compared to the control group ( P < 0.05 or P < 0.01 ).There was no severely side effect found in this trial.Conclusion Songling Xuemaikang Capsule could partly improve patients clinical outcome and life quality.The clinical efficacy of Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent should be related to its functioning to promote the recovery of patients' blood hemorheology,and regulate serum lipid and decrease CRP level.
4.The study of ~(99m)T_C-sulphur colloidal particles’ properties and internal mammary sentinel nodes lymphoscintigraphy
China Oncology 2006;0(08):-
Background and purpose:Internal mammary sentinel nodes (IMSNs) lymphoscintigraphy could guide in ?-detecting and removing the IMSNs for the purpose of biopsy during the operation,which is helpful to determine the necessity of postoperative radiotherapy. However,IMSNs imaging rate remains low if using axillary lymph nodes (ALNs) lymphoscintigraphy. This study was to investigate the tracer’s properties and try to improve the IMSNs imaging rate through changing the label procedure. Methods:The boiling time of 99mTC-sulphur colloidal particles was shortened from 3~5 minutes to 2 minutes during the label procedure, then the colloidal particles’ diameter, distribution and stability were observed by Transmission Electron Microscope (TEM), then the IMSNs lymphoscintigraphy was performed. Results:This colloidal tracer’s shape and distribution remained stable for 3 hours, and 90% of the particles had a diameter of 10 nm, the particles tended to aggregate afterwards. 4 hours after labeling, the diameter of particles exceeded 100 nm. IMSNs could be clearly imaged if the tracer was freshly used (within 3 hours after labeling). Conclusion:Within 3 hours after the labeling the unfiltered colloidal tracer with modified procedure, the particle could be used and internal mammary lymph nodes could be imaged more clearly.
7.Cardiac sodium channelopathy from bench to bedside.
Chinese Journal of Pediatrics 2013;51(11):874-877
Arrhythmias, Cardiac
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diagnosis
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genetics
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pathology
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Brugada Syndrome
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diagnosis
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genetics
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pathology
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Channelopathies
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diagnosis
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genetics
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pathology
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DNA Mutational Analysis
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Electrocardiography
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Genetic Testing
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Heart Conduction System
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physiopathology
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Humans
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Infant
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Long QT Syndrome
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diagnosis
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genetics
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pathology
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Muscle Proteins
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genetics
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Mutation
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NAV1.5 Voltage-Gated Sodium Channel
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genetics
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Sodium Channels
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genetics
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Sudden Infant Death
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etiology
8.The therapeutic effect of Shuxuening injection on acute cerebral infarction and its mechanism
Hong ZHANG ; Min ZHOU ; Junjian ZHANG
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
Objective:To investigate the therapeutic effect of traditional Chinese medicine,Shuxuening injection on the treatment of acute cerebral infarction and its mechanism.Methods:Patients in the treatment group(n=60) and control group(n=58) were injected with Shuxuening injection and Danshen injection respectively.The treatment period of two group lasted 2 weeks.The clinical therapeutic effects,neurological functional deficit scores(NFDS) and Barthel index,hemorheology indexes,serum lipid,nitric oxide and endothelin had been evaluated in both groups before and after 2 weeks treatment,except Barthel index which was accessed in both groups before treatment and 4 weeks later.Results:After 2 weeks treatment,the total clinical effective rate in treatment group and control group was 88.4% and 70.7%(P