1.A Supplementary LED Alarm System for Siemens StreamLab
Min CHEN ; Hailing QIU ; Lei CHEN
Chinese Medical Equipment Journal 2003;0(11):-
Objective To help the operator to find the alarm of Siemens StreamLab as quickly as possible. Methods Based on serial port control with VB 6.0 program, the system can catch the change of the control screen's special point and control the serial port to change the condition of the appointed pin to get a DC voltage to turn the LED on. Results The translation was implemented from screen icon alarm to LED alarm. Conclusion The LED alarm system can help the operator to observe the alarm of Siemens StreamLab promptly.
2.Empirical Analysis on Medical Ethics in the United Nations Peacekeeping Medical Support
Chinese Medical Ethics 2017;30(7):802-804,809
In the peacekeeping operations of the United Nations,medical personnel need to have clear legal compliance to solve the ethical problems encountered.The existing laws and regulations are impractical with a nar row cover,which can't meet the actual requirements.Based on the literatures and practical examples,this paper discussed the medical ethical problems involved in peacekeeping operations using the three-step method (empirical investigation,comparative analysis and summarization),and provided suggestions and countermeasures to the construction of medical ethics in peacekeeping medical support.
3.Efficacy analysis of zoledronic acid combined with radiotherapy and combined with chemotherapy for bone metastasis of non-small cell lung cancer
Huibing QIU ; Tienan YI ; Lingyun ZHANG ; Lin LEI ; Min SU
Cancer Research and Clinic 2017;29(7):437-441
Objective To observe and compare the curative effects of zoledronic acid (ZA) combined with radiotherapy and ZA combined with chemotherapy in the treatment of bone metastasis of non-small cell lung cancer (NSCLC). Methods Seventy-eight patients with NSCLC bone metastasis treated by radiotherapy or chemotherapy were taken in our hospital from January 2010 to June 2014, including 39 cases of ZA combined conventional fractionation radiotherapy (radiotherapy combined group), and 39 cases of ZA combined with chemotherapy (paclitaxel liposome + cisplatin) (chemotherapy combined group). Each group had 39 cases. WHO objective evaluation standard, efficacy evalulation of solid tumor metastasis and curative effect standard grading of pain, anticancer agent toxicity classification standard, Karnofsky standard were used for evaluating and analyzing the patients with primary lung tumor, bone metastasis, degree of pain, adverse reactions and functional status (once before and after the treatment). Results The efficiency rate of primary lung tumor, the efficiency rate of bone metastasis, the total effective rate of pain relief and the improvement rate of functional status (Karnofsky score increased by 10 points or more)in the radiotherapy combined group and chemotherapy combined group were 82.05 % (32/39) vs. 79.49 % (31/39), 48.72 % (19/39) vs. 51.28 %(20/39), 82.05 % (32/39) vs. 84.62 % (33/39), 66.67 % (26/39) vs. 71.79 % (28/39) respectively, and the differences were not statistically significant (the values of x2 were 0.224, 0.237, 0.195, 0.259 respectively, all P> 0.05); Although the two groups showed low-grade fever, bone marrow suppression, esophagitis, liver and kidney damage, gastrointestinal reactions and other adverse reactions, the adverse reactions of two groups were close to [28.21 % (11/39) vs. 30.77 % (12/39)] (x2 = 0.314, P> 0.05). Fortunately, these reactions were controlled well after symptomatic treatment. Conclusion ZA combined with radiotherapy or chemotherapy is a safe and effective way for bone metastasis of NSCLC, which should be taken based on the individual condition of the patients.
4.Expression of mCD_(14) on Alveolar Macrophage of Neonates with Respiratory Distress Syndrome Treated by Me-chanicalventilation
li-min, KANG ; lei, CAO ; cui-qing, LIU ; xi-qun, JIA ; qiu-jin, LIANG
Journal of Applied Clinical Pediatrics 2003;0(10):-
Objective To investigate the mechanism of mCD14 expression on AM in the pathogenes of neonatal respiratory distress syndromes( NRDS). Methods The expression of mCD14 on AM was analyzed with flow cytometry. Enzyme - linked immunosorbent assay was performed for detecting the concentration of IL- 1? and IL-8.Results The percentage of mCD14 positive AM in experimental group [(54.772 ?17 .341)%] was higher than that in control group [(14.023? 10. 713)% ](t= -7.739 P
5.The experience of diagnosis and treatment for clear cell papillary renal cell carcinoma
Min QIU ; Jian LU ; Lulin MA ; Min LU ; Lei ZHAO ; Xiaofei HOU ; Guoliang WANG ; Shaohui DENG ; Ye YAN
Chinese Journal of Urology 2016;37(9):655-659
Objective To discuss the clinic characters of clear cell papillary renal cell carcinoma ( CCPRCC) and the efficacy of related laparoscopic surgery.Methods From October 2013 to December 2015, 4 cases were treated as CCPRCC including 3 male and 1 female.Their age ranged from 34 to 67 years old ( mean 53 years old) .The duration of illness ranged from 7 days to 3 months, which the average duration was 1.5 months.The location of tumor included left side in 2 cases and right side in other 2 cases.All tumors were found incidentally, without symptoms or positive sign.Ultrasound showed that 2 cases were solid, and the other 2 cases were cystic solid with low, high or mixed echo and rich blood flow signals.The tumors were enhanced in CT arterial phase, and calcification showed in one case.MRI showed heterogeneous signal.The mean size of tumor was 3.0 cm,ranging 2.3 to 4.5 cm.After preoperative examination, all cases underwent retroperitoneal laparoscopic partial nephrectomy.During the operation, 2 cases were confirmed as cystic solid tumors, and the other 2 cases were solid tumors.Renal artery and renal mass were dissociated , then the artery was blocked.The tumor was complete resected, and kidney was sutured. Results All surgery was performed successfully without conversion.The operation time was 137-191 min (average 157 min).The blood loss was 10-100 ml (average 45 ml) without blood transfusion.The warm ischemia time was 15-35 min ( mean 22 min) .The postoperative hospitalization time stay 6-8 d ( average 7 d).Pathologic report was CCPRCC, including 3 cases of WHO/ISUP grade 1, and 1 case of WHO/ISUP grade 2.2 cases were cystic solid tumor, and other 2 cases were solid tumor.Bland-appearing tubules and occasional small papillae, and uniform small nuclei are arranged in a linear manner away from the basal aspect of the tubules in microscope.Immunohistochemistry showed that CA IX, CK7, 34 E12 were positive, but CD10 , P504S and CD117 were negative.The mean duration of postoperative follow-up was 14 months, ranging 4 to 30 months.No recurrence was found in those patients.Patients were followed up for 4-30 months ( average 14 months) without recurrence or metastasis.Conclusions CCPRCC is a rare subtype of renal tumor, which mainly diagnosed by pathological diagnosis . Retroperitoneal laparoscopic partial nephrectomy is an effective method for the treatment with good prognosis.
6.The mini-invasive surgical treatment for cholelithiasis disease experiences in the primary hospital
Min LI ; Weijun DENG ; Xiaodong LEI ; Peicai QIU ; Suming LI ; Zhanbin CHEN ; Zhixiong PAN ; Zhiqiu ZHOU ; Xuan LIU
Chinese Journal of Primary Medicine and Pharmacy 2009;16(4):616-617
Objective To study the mini-invasive surgical treatment for cholelithiasis disease in the primary hospital. Methods Laparoseope,duodenoscope and choledochoscope were combined to treat 293 cases with cholelith-iasis which included 2 cases cholecystolithisasis, 131 cases were cholecystolithiasis with secondary choledocholith,28 cases with primary choledocholith,39 cases with calculus of intrahepatic duct,93 cases with calculus of intrahepatic or extrahepatic duct. Results The program had minor trauma, mild suffering, and less operative complications,compared with traditional open operations. Conclusion The combined treatment of laparoscopy, duodenoscopy, choledochoscope and surgery for the cholelithiasis in the primary hospital is feasible, safe and effective.
7.Effects of electroacupuncture on the proprioception of athletes with functional ankle instability.
Yan ZHU ; Min-lei QIU ; Ying DING ; Yi QIANG ; Bei-ying QIN
Chinese Acupuncture & Moxibustion 2012;32(6):503-506
OBJECTIVETo observe the efficacy differences between electroacupuncture and physiotherapy on the proprioception of athletes with functional ankle instability (FAD.
METHODSFifty athletes with FAI were randomly divided into an electroacupuncture group and a physiotherapy group. The electroacupuncture group was treated with electroacupuncture at Jiexi (ST 41), Kunlun (BL 60), Qiuxu (GB 40) and Ashi acupoints, and the physiotherapy group was treated with low frequency electrical stimulation and infrared radiation at medial malleolus and lateral malleolus, thrice each week for consecutive 8 weeks. The Joint Position Sense: Active (JPSA), Joint Position Sense: Passive (JPSP) and Kinaesthesia (KT) were assessed at the ankle by use of Biodex System-III isokinetic dynamometer.
RESULTSThe JPSA of 11.090 +/- 3.1 degrees and the JPSP of 9.67 degrees +/- 2.8 degrees before the treatment reduced to 9.14 degrees +/- 4.0 degrees and 6.89 degrees +/- 3.3 degrees, respectively, after the treatment in the electroacupuncture group, with significant differences in JPSA and JPSP (both P < 0.05), compared with those in the physiotherary group, there were significant differences (both P < 0.05) and with no significant difference in KT (P > 0.05). There was no significant differences in the indices of JPSA, JPSP and KT in the physiotherapy group after 8 weeks than those before treatment (all P > 0.05).
CONCLUSIONElectroacupuncture can effectively improve the proprioception of athletes with FAI and achieves a superior efficacy as compared with the conventional physiotherapy.
Adult ; Ankle Injuries ; physiopathology ; therapy ; Ankle Joint ; physiopathology ; Athletes ; Electroacupuncture ; Female ; Humans ; Joint Instability ; physiopathology ; therapy ; Male ; Proprioception ; Young Adult
8.Clinical significance of human epidermal growth factor receptor family molecules expression in gastric cancer.
Gang LI ; Rong-min GU ; Xu WEN ; Xue-zhi MING ; Lei XIA ; Xin-yu XU ; Ji ZHANG ; Huan-qiu CHEN
Chinese Journal of Gastrointestinal Surgery 2013;16(7):668-672
OBJECTIVETo study the association of human epidermal growth factor receptor family molecules expression in gastric cancer tissues with the prognosis of patients with gastric cancer.
METHODSClinical data of 161 patients with gastric cancer undergoing gastrectomy in Jiangsu Cancer Hospital between January 2006 and January 2007 were analyzed retrospectively. The expression of HER1, HER2, HER3 and HER4 was detected by immunohistochemistry. Association of the expression of HER family with the prognosis of patients was examined. Kaplan-Meier method was used to analyze the survival.
RESULTSHigh expression rates of HER1, HER2, HER3 and HER4 were 46.0% (74/161), 10.6% (17/161),55.9% (90/161) and 68.3% (110/161) respectively. Univariate analysis revealed that high expression of HER3 was associated with tumor invasion depth, lymph node metastasis, stage, neurovascular invasion, and overall 4-year survival. High expression of HER4 was associated with tumor distant metastasis and stage. High co-expression of HER2 and HER3 was associated with overall 4-year survival (P=0.023). Multivariate analysis revealed that high expression of HER3 and stage were prognostic independent factors.
CONCLUSIONUp-regulated expression of HER3 is associated with the poor prognosis in gastric cancer patients.
Adult ; Aged ; Aged, 80 and over ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Prognosis ; Receptor, Epidermal Growth Factor ; metabolism ; Receptor, ErbB-2 ; metabolism ; Receptor, ErbB-3 ; metabolism ; Receptor, ErbB-4 ; Retrospective Studies ; Stomach Neoplasms ; metabolism ; pathology
9.Finite element analysis of a new shape memory alloy cervical hook for atlantoaxial instability.
Xiao-qiu SHU ; Lei WAN ; Chun-tang YU ; Tong YIN ; An-min JIN
Journal of Southern Medical University 2006;26(8):1197-1199
The mechanics of a new shape memory alloy cervical hook for atlantoaxial instability was analyzed with finite element method on the basis of a three-dimensional model reconstructed from the images of CT scanning of an adult cadaveric upper cervical at 1-mm interval. The stress and displacement of every nodule and element in the course of deformation of the internal fixation were tested, and the results showed that the cervical hook was strong enough against tensile stress, which concentrates in the middle of the device. The pull was 237.58 N at the loading point. With such mechanical performance, this cervical hook can be reliable for correction of atlantoaxial instability.
Adult
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Alloys
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Atlanto-Axial Joint
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Cadaver
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Finite Element Analysis
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Humans
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Joint Instability
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diagnostic imaging
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surgery
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Male
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Memory
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Orthopedic Fixation Devices
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standards
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Orthopedic Procedures
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instrumentation
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methods
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Radiography
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Reproducibility of Results
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Tensile Strength
10.Association of the ALOX5AP gene SG13S114 A/T polymorphism with atherosclerosis.
Ying-lei HE ; Xiao-ping JIN ; Min ZHU ; Xian-fang LIN ; Zong-lin XIE ; Qiu-yue CHEN
Chinese Journal of Medical Genetics 2010;27(2):186-189
OBJECTIVETo investigate the relationship between the polymorphism of SG13S114 A/T in the 5-lipoxygenase-activating protein (ALOX5AP) gene and the stability of carotid atherosclerosis.
METHODSPolymorphism of SG13S114 A/T in the ALOX5AP gene was analyzed in 152 cases of acute infarction with stable plaque, and 132 cases of acute infarction with vulnerable plaques, by using polymerase chain reaction and restriction fragment length polymorphism. Carotid artery plaque was analyzed by carotid artery color ultrasound.
RESULTSThe frequencies of SG13S114 AA genotype and the A allele in the vulnerable plaque group were higher than that in the stable plaque group (P< 0.01).
CONCLUSIONThe polymorphism of SG13S114 A/T in the ALOX5AP gene may be associated with the instability of atherosclerosis. And the SG13S114 A allele may be a risk factor of vulnerable plaques.
5-Lipoxygenase-Activating Proteins ; Aged ; Aged, 80 and over ; Carotid Artery Diseases ; genetics ; Carrier Proteins ; genetics ; Case-Control Studies ; Female ; Gene Frequency ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Membrane Proteins ; genetics ; Middle Aged ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Polymorphism, Single Nucleotide