Aged, 80 and over ; Comorbidity ; Deglutition Disorders ; physiopathology ; Diagnosis, Differential ; Humans ; Hyperostosis, Diffuse Idiopathic Skeletal ; physiopathology ; Male ; Pharyngeal Neoplasms ; diagnosis ; diagnostic imaging ; physiopathology ; Radiography

Aged, 80 and over ; Diagnosis, Differential ; Female ; Foreign Bodies ; complications ; diagnostic imaging ; Humans ; Radiography ; Sciatica ; diagnostic imaging ; Soft Tissue Injuries ; diagnostic imaging

Prader-Willi syndrome(PWS) was first described by Prader et al in 1956. This syndrome is characterized by diminished fetal activity, low birth weight, infantile hypotonia with feeding problem, temperature instability, early onset of childhood hyperphagia with consequent obesity, short stature, hypogonadism and mental retardation. The deletion of chromosome 15(del 15(qll-13)) was reported by Ledbetter in 1981, which was thought to be of paternal origin. Recently, such micro- deletion may be diagnosed by fluorescence in situ hybridization(FISH) that recognizes specific DNA base sequence. We experienced a Prader-Willi syndrome confirmed by FISH in an infant that had hypotonia, growth retardation, feeding difficulty and FUO since 1 month of age. We report this case with a brief review and related literature.
Base Sequence ; DNA ; Fetal Movement ; Fluorescence ; Humans ; Hyperphagia ; Hypogonadism ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; Intellectual Disability ; Muscle Hypotonia ; Obesity ; Prader-Willi Syndrome*

Fryns syndrome is a lethal syndrome of multiple congenital anomalies first described by Fryns et al in 1979. A recently developed major diagnostic criteria includes abnormal face, small thorax with widely spaced hypoplastic nipples, distal limb and nail hypoplasia, lung hypoplasia with diaphragmatic hernia, central nervous system anomalies and congenital heart disease. The pathogenesis of Fryns syndrome is not clear. Of the major immediate life-threatening abnormalities of this syndrome, lung hypoplasia associated with diaphragmatic hemia has usually proven to be fatal. We report a case of Fryns syndrome, which has the prenatal ultrasonographic findings of Dandy-Walker malformation and renal hypoplasia.
Central Nervous System ; Dandy-Walker Syndrome ; Extremities ; Heart Defects, Congenital ; Hernia, Diaphragmatic ; Lung ; Nipples ; Thorax

Polymorphous low-grade adenocarcinoma (PLGA) is a distinctive salivary gland neoplasm with a propensity to arise from minor salivary glands, particularly of the palate. Reports of PLGA have increased with the establishment of specific histopathological criteria characterizing the PLGA, but there are only a few reports of major salivary gland origin. PLGA shares histological features with adenoid cystic carcinoma, so histopathologic diagnosis is essential and immunohistochemistry is an important tool when making differential diagnosis. The treatment of choice is wide surgical excision, and long-term follow up is necessary to evaluate local recurrences. We herein report a case of PLGA arising in a submandibular gland with a review of the relevant literature.
Adenocarcinoma* ; Carcinoma, Adenoid Cystic ; Diagnosis ; Diagnosis, Differential ; Follow-Up Studies ; Immunohistochemistry ; Palate ; Recurrence ; Salivary Gland Neoplasms ; Salivary Glands ; Salivary Glands, Minor ; Submandibular Gland*

Hypertrophy of salivary gland was developed by sialadenitis, sialolithiasis, autoimmune diasease and other tumorous conditions. Mikulicz's disease has been used to describe symptomless hypertrophy of the salivary gland and lacrimal gland. In the past, it was thought that Mikulicz's disease is included within the diagnosis of Sjogren's syndrome. However, Mikulicz's disease represents Immunoglobulin G4 (IgG4)-related hypertrophy of salivary gland and lacrimal gland by an elevated level of IgG4 in the serum of the patient and good responsiveness to glucocorticoid, eventually leading to recovery of gland function. We have experienced a case of IgG4-related sialadenitis and dacryoadenitis with bilateral hypertrophy of parotid, submandibular and lacrimal glands. We report this case with a brief review of the literature.
Dacryocystitis ; Humans ; Hypertrophy ; Immunoglobulin G ; Immunoglobulins ; Lacrimal Apparatus ; Salivary Gland Calculi ; Salivary Glands ; Sialadenitis ; Sjogren's Syndrome

<0.05). 4. Histologic examination revealed that AM protected leukocyte infiltration and epithelial migration was nearly completed at 4 weeks. Terudermis(R) group showed mild neutrophil infiltration until 2 weeks and completion of epithelization at 4 weeks. Control group showed massive leukocyte infiltration until 4 weeks. 5. Microvessels were increased sharply at 1 week and control group at 1 and 4 week showed significant differences with Terudermis(R) group of same interval(p<0.05) but no differences were found with AM group(p<0.05). CONCLUSION: EGF and EGF-R were well preserved in freeze-dried AM. AM attached to collagen acted as excellent biologic dressing which had similar effect with Terudermis(R). AM showed anti-inflammatory action and healing was completed at 4 weeks after full-thickness skin defect.
Amnion* ; Animals ; Bandages* ; Biological Dressings ; Collagen* ; Epidermal Growth Factor ; Leukocytes ; Microvessels ; Neutrophil Infiltration ; Rats* ; Skin ; Wound Healing* ; Wounds and Injuries*

Absorption ; Alveolar Process ; Animals ; Bone Regeneration ; Collagen ; Collagen Type I ; Giant Cells ; Lymphocytes ; Membranes ; Osteogenesis ; Rats ; Rats, Sprague-Dawley ; Transplants

BACKGROUND: During anesthesia in children sometimes we are confronted with airway obstruction, due to for example laryngospasm or stridor just after tracheal extubation. The use of intravenous lidocaine to prevent laryngospasm or stridor is controversial. This study was undertaken to investigate the effect of intravenous lidocaine on the prevention of laryngospasm or stridor by checking oxygen saturation using a pulse oximeter. METHODS: Sixty children undergoing strabismus surgery with general anesthesia (N2O-O2-enflurane) were divided into two groups, the L group (n = 32) received intravenous lidocaine 1 mg/kg, and the S group (n = 28) received the same amount of saline, both 5 minutes before extubation. The maximal and minimal levels of oxygen saturation were checked in the operation room and in the post anesthetic recovery room (PAR) after tracheal extubation. The numbers of patients with have oxygen saturation of less than 95% were counted in each group. Respiratory depression and sedation scores were noted at PAR in both groups. RESULTS: The number of cases that experienced laryngospasm or stridor was 4 (12.5%) in the L group and 3 (10.7%) in the S group, showing no significant difference. No respiratory depression was observed in either group and no difference in the sedation scores 5, 15, 30 minutes after arrival at PAR was observed between two groups. CONCLUSIONS: The intravenous administration of lidocaine 1 mg/kg 5 minutes before extubation in strabismus surgery did not prevent laryngospasm or stridor.
Administration, Intravenous ; Airway Extubation ; Airway Obstruction ; Anesthesia ; Anesthesia, General ; Child ; Humans ; Laryngismus* ; Lidocaine* ; Oxygen ; Recovery Room ; Respiratory Insufficiency ; Respiratory Sounds* ; Strabismus*

Although it has been accepted that metoclopramide provides the effects of antiemetics, enhance- ment of intestinal motility and acts as antagonist on dopamine receptor, there is still controversy over inhibitory action of plasma cholinesterase. We examined the effect of preoperative intravenous administration of metoclopramide 10mg (group 2,4) on the duration of neuromuscular block induced by an intubating dose (1 mg/kg) of succinylcholine. Forty female adult patients were devided into four groups, scheduled for cesarean section (group 3,4) or other elective operations (group 1,2). The 1 H2single twitch height of the adductor pollicis muacle was recorded on paper to 1 H2single twitch stimulus by a nerve stimulator (Accelograph). The patients in group 2 and 4 received metoclopramide 10 mg i.v followed by succinylcholine 1mg/kg, and the patients in group 1 and 3 received succinylcholine 1mg/kg alone. The time from disappearance of 1 H, single twitch height to reappearance of that did not significantly differ between group l and 3. However, there was significant prolongation of the time from disappearance of 1H2single twitch height to reappearance of that in patients who received metoclopramide followed by succinylcholine in group 2 and 4. Also, we examined the effect of preoperative intravenous administration of metoclopramide 10mg on the duration of neuromuscular block by 0.5mg/kg of succinylcholine in twenty female patients for elective operations (group 5,6). There was no significant prolongation of the time from disappearance of 1 H, single twitch height to reappearance of that.
Administration, Intravenous ; Adult ; Antiemetics ; Cesarean Section ; Cholinesterases ; Female ; Gastrointestinal Motility ; Humans ; Metoclopramide* ; Neuromuscular Blockade ; Plasma ; Pregnancy ; Receptors, Dopamine ; Succinylcholine*