2.Familial IgA nephropathy.
Chinese Journal of Pediatrics 2003;41(11):863-864
5.Diagnosis and prognosis of systemic juvenile rheumatoid arthritis.
Li-hua SHAO ; Min WEI ; Mei DONG
Chinese Journal of Pediatrics 2003;41(1):46-47
Arthritis, Juvenile
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classification
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diagnosis
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therapy
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Child
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Female
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Follow-Up Studies
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Humans
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Male
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Prognosis
7.Clinical study of terminating biochemical pregnancy and early clinical pregnancy with mifepristone and misoprostol
Cui-Lan LI ; Min WEI ; Mei-Fang FU ; Min LI ;
Chinese Journal of Obstetrics and Gynecology 2001;0(08):-
Objective To explore the efficacy and safety of terminating biochemical pregnancy (the stage in which intrauterine or ectopic pregnancy cannot be confirmed) with mifepristone and misoprostol. Methods Mifepristone (150 mg) combined with misoprostol (600 ?g) 3 days later were given to 500 biochemical pregnancies (G_1),500 early clinical pregnancies (G_2) and 500 clinical pregnancies (G_3) which were classified according to amenorrhea days,serum human chorionic gonadotropin-beta subunit (?- hCG) and vaginal B-ultrasonic examinations.All were observed for 6 hours after taking misoprostol and returned for assessment per week.Results Expulsion of conceptus was G_1 123 (24.6%,123/500),G_2 438 (87.6%,438/500) and G_3 467 (93.4%,467/500).Failure rate was G_1 6 (1.2%,6/500),G_2 24 (4.8%,24/500) and G_3 79 (15.8%,79/500) for ongoing pregnancies,hospitalizations for suspected ectopic pregnancies and surgical intervention for heavy or long-time bleeding.Bleeding cases during the administration of mifepristone were G_1 272 (54.4%,272/500),G_2 141 (28.2%,141/500) and G_3 87 (17.4%,87/500);the mean bleeding days were G_1 (5.8?1.5),G_2 (9.0?2.9) and G_3 (14.3?5.9) days.Other side effects including abdominal pain,nausea,vomiting and diarrhea were low and light in each group,increasing with advancing gestational age.Menses recovery was 486 (97.2%,486/500),452 (90.4%,452/500) and 433 (86.6%,433/500) for each group on scheduled time.Satisfaction was 499 (99.8%,499/500),485 (97.0%,485/500) and 369 (73.8%,369/500) respectively.Conclusion Mifepristone and misoprostol in combination is as safe,and effective for termination of biochemical pregnancies as ordinary medical abortion.It does not need to wait till ectopie pregnancy is excluded.
8.Research on the change of cyclin-dependent kinase 5 in hippocampus CA1 after conditioned fear extinction
Lili ZHANG ; Min LI ; Peipei LI ; Mei WEI
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(4):293-295
Objective To investigate the change of cyclin-dependent kinase 5(CDK5)during 1 week after conditioned fear extinction.Methods Forty-two male adult SD rats were randomly divided into native group,extinction control group and 24h extinction group.Extinction retention test and immunohistochemistry of CDK5 of hippocampus were done at 1st,3rd,7th day after fear extinction.The numbers of CDK5 positive cell in hippocam-pus CAI was measured by computer analytic system.Results (1)Extinction retention scores were increasedgradually in extinction group compared with native group(75.60±2.51)%,the scores of extinction control group was decreased at 1st day(15.62±10.28)% and 3th day(20.58±7.79)% after extinction(P<0.01);24h extinction group(71.04±11.65)% were better than extinction control group(35.48±12.37)at 7th day after extinction(P<0.01).(2)The number of CDK5 positive cell was increased significantly in 24h extinction group (24.94±5.20;32.25±6.14;33.28±6.56)compared with native group(75.60±2.51;P<0.01).In 24h extinction group the number was increased significantly at 3rd day(P<0.01)and 7th day(P<0.05)compared with extinction control group(25.09±4.83;26.70±4.57),and decreased at 1st day compared to 3rd day(P<0.05)and 7th day(P<0.01).Conclusion From 1st to 7th day after extinction,CDK5 may contribute to the retention of fear extinction in hippocampal CA1.
9.The significance of quantitative temperature sense thresholds in diagnosis of small fibrous sensory neuropathy in patients with type 2 diabetes.
Hou-min YIN ; Wei FENG ; Mei-ping DING
Chinese Journal of Applied Physiology 2015;31(2):150-153
OBJECTIVETo evaluate the small fiber function in patients with type 2 diabetes mellitus of the early stage by measuring the sensory threshold with the quantitative temperature testing technology.
METHODSTwenty cases of patients with type 2 diabetes with no neurological deficit (DM group) and twenty age and sex-matched healthy controls underwent the detecting of cold sensory threshold (CST), warm sensory threshold (WST), cold pain threshold (CPT), heat pain threshold (HPT) in both inside of their hands.
RESULTSThere was no significant difference in CST, WST, CPT and HPT between left and right inside of hand of the same sample among all the testers. But the four kinds of threshold showed significant difference in the right inside of hand between patients and healthy people ( P < 0.05). In addition, the CST and WST differed significantly in the left inside of hand between the patients and healthy controls while the CPT and HPT showed no significant difference in the left inside of hand between them. Patients group and control group with CST and WST on the left side of the comparison difference was statistically significant (P < 0.05).
CONCLUSIONQuantitative analysis of temperature sense threshold can not only reflect increase of the pain threshold value, also can reflect its decrease, i. e. hyperalgesia, which may help to diagnose small fibrous peripheral neuropathy recognition, especially in early diabetic peripheral neuropathy.
Case-Control Studies ; Cold Temperature ; Diabetes Mellitus, Type 2 ; physiopathology ; Diabetic Neuropathies ; diagnosis ; Hot Temperature ; Humans ; Hyperalgesia ; Pain Threshold ; Sensory Thresholds ; Thermosensing