1.Analysis of diagnosis and treatments of acute mesenteric ischemic disease of 15 cases
Chinese Journal of Primary Medicine and Pharmacy 2009;16(9):1566-1567
Objective To investigate the clinical features, diagnosis and treatment of acute mesenteric isehe-mic disease. Methods Clinical data of 15 patients with acute mosenteric ischemic disease were analyzed retrospective-ly. Results Operation was performed on 14 patients and 1 patient received conservative treatment, 9 cases recovered and 5 died postoperatively. Conclusion Color ultrasound and selective angiography are effective examinations for early diagnosis of acute mesenterie ischemic disease. Early resection of necrotic bowel and application of anticoagulant post-operatively are effective to reduce the mortality. Conservative treatment is still effective for elective patient.
2.Clinical analysis of 79 gastrointestinal tract stromal tumor cases.
Zi-min LIU ; Jun LIANG ; Zhuang YU
Chinese Journal of Oncology 2011;33(7):552-553
Adult
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Aged
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Antineoplastic Agents
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therapeutic use
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Benzamides
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Chemotherapy, Adjuvant
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Female
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Follow-Up Studies
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Gastrointestinal Neoplasms
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drug therapy
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surgery
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Gastrointestinal Stromal Tumors
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drug therapy
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secondary
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surgery
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Humans
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Imatinib Mesylate
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Liver Neoplasms
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secondary
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Male
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Middle Aged
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Neoplasm Recurrence, Local
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Piperazines
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therapeutic use
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Pyrimidines
;
therapeutic use
4.The attitude towards people living with HIV and AIDS(PLWHA) and AIDS knowledge and desire for AIDS related training among 1292 health workers in selected hospitals in Beijing
Chinese Journal of AIDS & STD 2006;0(02):-
Objective To understand the attitude of health workers towards people living with HIV and AIDS(PLWHA) and AIDS knowledge and desire for related training among them in selected hospitals in Beijing.Method Convenience sampling was used to select health workers from 32 hospitals of different levels in 4 districts within Beijing.Anonymous self-administrated questionnaires were used to collect the information regarding AIDS knowledge and desire for relevant training.Results A total of 1 292 health workers completed the questionnaire.They demonstrated a moderate level of general AIDS knowledge,but a low level of knowledge related to AIDS diagnosis and therapy.Of them 39.7% had received specialized AIDS training and 96% had strongly desire for such specialized training.Most health workers sympathized with PLWHA and understood their situation,while some of them were afraid of PLWHA and wanted to have minimal contact with PLWHA.91.3% of the health workers expressed that PLWHA should have the same rights to medical services.At the same time,49.2% of the health workers stated that they would not like to work in hospitals or departments which accepted PLWHA.80% of the health workers expressed concern over acquiring HIV infection in the workplace.52.7% of them thought that they had a risk of becoming infected in the workplace.Conclusion The level of AIDS knowledge among health workers in Beijing needs to be improved.Specialized training to enhance and develop health workers knowledge of prevention,diagnosis and treatment of AIDS is required.Most of the health workers do not discriminate against PLWHA,but they express concern over infection in the workplace.
6.The Anti-oxidation Activity and Liver Damage Induced by Chronic Fluorosis in Male Rats
Shu-Jun CHEN ; Yu-Min SUN ; Yu-Jun MENG ; Al ET ;
Journal of Environment and Health 2007;0(08):-
Objective To know the relationship between the changes of total anti-oxidation capacity (T-AOC),nitric oxide (NO) and nitric oxide synthase (NOS) the liver and liver damage induced by chronic fluoride exposure.Methods Eighteen male Wistar rats were randomly divided into 3 groups,control(treated with tap water),low fluoride(LF,treated with NaF at 100 mg/L) and high fluoride (HF,treated with NaF at 200 mg/L),6 in each group.Fluoride was given through drinking water.During the period of exposure,the body was weighed and after 6 months of treatment,the rats were killed,the liver coefficient was calculated,T-AOC, NO and NOS in the livers were determined respectively.Results Compared with the control,the liver coefficient,NO and NOS in the fluoride treated groups significantly increased (P
7.Different active ingredients of medicinal plant based on function differentiation of homologous gene.
Yuan YUAN ; Jun YU ; Lu-qi HUANG ; Xu-min WANG
China Journal of Chinese Materia Medica 2015;40(6):1023-1026
In the research field of quality control in Chinese medicinal materials, variation in active ingredients of medicinal plant is always the key and hot issues. With the development of high-throughput sequencing technologies and reducing cost, a large numbers of genes from medicinal plant were cloning and provide a solid foundation for further research of gene structure and its biological function, and also provides conditions for explore active ingredient variation and its quality control from the perspective of molecular pharmacognosy. This paper introduces the concept of homologous gene, gene duplication and classification. We prospect the function of duplicated genes in the role of molecular mechanism research about variation in active ingredients, aiming at providing a new way for medicinal materials quality control.
Drugs, Chinese Herbal
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analysis
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Gene Duplication
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Plant Proteins
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genetics
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Plants, Medicinal
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chemistry
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genetics
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Quality Control
8.Meta-analysis of phacoemulsification versus phacotrabeculectomy for primary angle closure glaucoma with cataract
Hong-yang, ZHANG ; Min-bin, YU ; Zhong-jun, DUN
Chinese Journal of Experimental Ophthalmology 2013;(3):270-274
Background Increase of lens thickness at incipient cataract is a key factor of onset of primary angle-closure glaucoma (PACG).Phacoemulsification (Phaco) or phacotrabeculectomy (Phacotrabe) have been documented to be effective for the patients of PACG associated with cataract.However,which surgery is more effective and safe is lack of evidence.Objective This study was to assess and compare the clinical effectiveness of Phaco versus Phacotrabe for PACG with cataract.Methods The relevant literature was searched electronically from the PubMed (1966 to June 2011),EMB Reviews (1966 to June 2011) and Cochrane Library (Issue 1,2011).The manually searching of relevant conference proceedings was used as the supplement.The articles of randomized controlled trial (RCT) about the clinical effectiveness of Phaco versus Phacotrabe for PACG with cataract were included.The methodology quality of included literature was graded.The analysis indexes included intraocular pressure (IOP)-lowing range,postoperative administration of glaucoma drugs,incidence of positive complication,postoperative best corrective visual acuity (BCVA) and perimetry damage.The RevMan4.2 software from Cochrane Collaboration was used for the Meta analyses.Results Three RCTs about phaco versus Phacotrabe for PACG with cataract were selected in this study with the 164 eyes of 164 cases.Meta analysis showed that the IOP-lowing range was larger in the Phacotrabe group compared to only Phaco group with the WMD of 1.17 and 95% CI of 0.06-2.27 (P =0.040),and the drug dosage of anti-glaucoma was less in the Phacotrabe group in comparison with the Phaco group with the WMD of 0.5 and 95% CI of 0.24-0.77 (P =0.000).However,the incidence of postoperative complication was higher in the Phacotrabe group than that of the Phaco group with the RR of 0.08 and 95% CI of 0.02-0.33 (P =0.000).No significant difference was found in the BCVA (WMD =0,95% CI:-0.13-0.13,P=1.00) andperimetry (WMD =1.01,95%CI:0.56-1.82,P=0.98).Conclusions Compared with Phaco,Phacotrab has a better IOP-lowing effectiveness and slightly worse safety.Phaco and Phacotrab have a fairly influencc in the postoperative BCVA and perimetry.As the sample sizes of the included trials are relatively small,more welldesigned large-scale RCTs are needed.
9.Key factor analysts for excessive fast rise of medical expenses
Aitian YIN ; Jun LI ; Zhenjie YU ; Min TANG ; Chengxiu LI
Chinese Journal of Hospital Administration 2009;25(5):305-307
Excessive and fast rise of medical expenses in China recent years has worsened the financial burden of both the government and individuals alike,making it a hotspot issue countrywide.To alleviate the difficulties of "accessibility to medical services" and "poverty or repoverty resulting from sickness" faced by the Chinese people at large,we built a multi-factor analysis model to identify key factors contributing to such a fast rise of medical expenses based on an analysis of the medical expenses in Shandong Province.In addition,we discussed the causes for GDP and headcount of medical staff in relation to the rise of medical expenses,and the strategies to curb expenses.